53156-6

Methionine/Phenylalanine [Molar ratio] in DBS

Active

Term Description

Methionine/Phenylalanine is a primary marker for Homocystinuria, Hypermethioninemia, Methylene tetrahydrofolate reductase deficiency, Methylcobalamin deficiency and Homocystinuria-megaloblastic anemia. Secondary marker for Methylmalonic aciduria and homocystinuria.
Source: Regenstrief LOINC

Part Descriptions

LP15730-2 Methionine
Methionine is an essential nonpolar amino acid, and a lipotropic. Methionine and cysteine are the only sulfur-containing proteinogenic amino acids. The methionine derivative S-adenosyl methionine (SAM) serves as a methyl donor. Methionine plays a role in cysteine, carnitine and taurine synthesis by the transsulfuration pathway, lecithin production, the synthesis of phosphatidylcholine and other phospholipids. Improper conversion of methionine can lead to atherosclerosis. Methionine, a chelating agent, is one of only two amino acids encoded by a single codon (AUG) in the standard genetic code (tryptophan, encoded by UGG, is the other). The codon AUG is also significant, in that it carries the Start message for a ribosome to begin protein translation from mRNA. As a consequence, methionine is incorporated into the N-terminal position of all proteins in eukaryotes and archaea during translation, although it is usually removed by post-translational modification. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Methionine (Wikipedia)

LP70160-4 Phenylalanine
Phenylalanine is an essential alpha-amino acid. It exists in two forms, a D and an L form, which are enantiomers (mirror-image molecules) of each other. It has a benzyl side chain and its name comes from its chemical structures that consists of a phenyl group substituted for one of the hydrogens in the side chain of alanine. Because of its phenyl group, phenylalanine is an aromatic compound that at room temperature exists as a white, powdery solid. L -phenylalanine (LPA) is an electrically-neutral amino acid and its enantiomer, D -phenylalanine (DPA), can be synthesized artificially. L -phenylalanine can also be converted into L -tyrosine, another one of the twenty protein-forming amino acids. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Phenylalanine (Wikipedia)

LOINC Names Get Info

Fully-Specified Name: Methionine/Phenylalanine:SRto:Pt:Bld.dot:Qn:
Long Common Name: Methionine/Phenylalanine [Molar ratio] in DBS
Short Name: Methionine/Phe DBS-sRto
Display Name: Methionine/Phenylalanine (DBS) [Molar ratio]
Consumer Name Alpha Get Info: Methionine/Phenylalanine, Dried blood spot

Part Model Get Info

Component
Methionine/Phenylalanine
LP286518-8
- Analyte
  Methionine/Phenylalanine
  LP286518-8
  - Component Numerator
    Methionine
    LP15730-2
    - Component Numerator Core
      Methionine
      LP15730-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Phenylalanine
    LP70160-4
    - Component Denominator Core
      Phenylalanine
      LP70160-4
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SRto
LP6868-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Bld.dot
LP21304-8
- System Core
  Bld.dot
  LP21304-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.24
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
53261-4	Amino acid newborn screen panel
54089-8	Newborn screening panel American Health Information Community (AHIC)

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Methionin/fenylalanin:Látkový poměr:Časový bod:Suchá krevní kapka (DBS):Kvantitativní:
de-DE	German (Germany)	Methionin/Phenylalanin:Stoffmengenverhältnis:Zeitpunkt:Blut.Tropfen:Quantitativ:
el-GR	Greek (Greece)	Μεθειονίνη/Φαινυλαλανίνη:SRto:Pt:Bld.dot:Qn: Synonyms: Bld.dot CHEM Pt Qn SRto Αίμα Μεθειονίνη Φαινυλαλανίνη
es-ES	Spanish (Spain)	Metionina/Fenilalanina:Relacion de Sustancia:Punto temporal:gota de sangre (papel de filtro):Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Metionina / Fenilalanina:Proporción de sustancia:Punto temporal:DBS:Cuantitativo:
fr-CA	French (Canada)	Méthionine/Phénylalanine:Ratio de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
fr-FR	French (France)	Méthionine/phénylalanine:Moles ratio:Ponctuel:Sang buvard:Numérique:
fr-BE	French (Belgium)	Méthionine/Phénylalanine:Ratio de substance:Temps ponctuel:Sang sur papier filtre:Quantitatif:
it-IT	Italian (Italy)	Metionina/Fenilalanina:Srto:Pt:Sangue.su carta da filtro:Qn: Synonyms: Chimica Punto nel tempo (episodio) Rapporto di sostanza Sangue Spot sangue secco
nl-NL	Dutch (Netherlands)	methionine/fenylalanine:molaire verhouding:moment:gedroogde bloedspot:kwantitatief: Synonyms: phenylalanine
pt-BR	Portuguese (Brazil)	Metionina/Fenilalanina:SCrto:Pt:SgPapel:Qn: Synonyms: Met; Phe; PPA; sRto; Substance concentration ratio; Point in time; Random; DBS; Filter paper; FP; Dried blood spot; Blood; WB; Whole blood; Quantitative; QNT; Quant; Quan; Chemistry; PKU
ru-RU	Russian (Russian Federation)	Метионин/Фенилаланин:МольОтн:ТчкВрм:Кр.Сух.капл:Колич: Synonyms: Количественный Кровь Кровь сухая капля Мольная доля;Молярная доля;Отношение концентраций Точка во времени;Момент
tr-TR	Turkish (Turkey)	Metiyonin/Fenilalanin:SOrn:Zmlı:Kan.nokta:Kant: Synonyms: SubsOranı
zh-CN	Chinese (China)	蛋氨酸/苯丙氨酸:物质的量比率:时间点:全血.斑点:定量型: Synonyms: Met;甲硫基丁氨酸;甲硫氨酸 Phe Phe;PPA;苯基丙氨酸 PKU 全血斑点(滤纸);滤纸;血液.斑点;血液斑点(滤纸) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间物质的量比值;物质的量比;摩尔比;摩尔比率;摩尔比值苯丙酮尿苯丙酮尿症苯丙酮酸尿症血;血液

Example Units

Unit	Source
{Ratio}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.