Version 2.78

Part Description

LP32458-9   von Willebrand factor cleaving protease
von Willebrand factor (vWF) cleaving protease, or ADAMTS13, is a metalloprotease that cleaves vWF and thereby limits platelet aggregation and formation of microthrombi. vWF cleaving protease inhibitors can decrease the protease activity and/or more rapidly remove the enzyme from the circulation. Such inhibitors are one cause of thrombotic thrombocytopenic purpura (TTP), a disorder characterized by thrombocytopenia, anemia, fever, and neurologic and renal abnormalities. Idiopathic TTP is often due to anti-ADAMTS13 autoantibodies, while inherited TTP is an autosomal recessive disorder due to mutations in the ADAMTS13 gene that lead to impaired protease function. Work-up of patients with TTP can include vWF cleaving protease activity and, if that activity is low, inhibitor screen followed by quantification. PMID: 18756543 Source: Regenstrief LOINC

Fully-Specified Name

Component
von Willebrand factor cleaving protease actual/normal
Property
RelCCnc
Time
Pt
System
PPP
Scale
Qn
Method
Chromo

Additional Names

Short Name
vWF Cp Act/Nor PPP Chro
Display Name
vWf cleaving protease actual/normal Chromogenic method (PPP) [Rel catalytic activity/Vol]
Consumer Name Alpha Get Info
vWf cleaving protease actual/normal, Blood

Basic Attributes

Class
COAG
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.73
Order vs. Observation
Both
Common Test Rank Get Info
3826

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: ADAMTS 13 Aktivität
es-ES Spanish (Spain) Proteasa divisora del Factor de von Willebrand actual/normal:Concentración catalítica relativa:Punto temporal:Plasma pobre en plaquetas:Qn:Cromogénico ( Enzima)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) proteasa de escisión del factor von Willebrand real / normal:Concentración catalítica relativa:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:Cromogénico (enzima)
fr-CA French (Canada) Protéase clivage du Facteur von Willebrand, Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Chromogénique
fr-FR French (France) Facteur Willebrand protéase Patient (%):Activité catalytique relative:Ponctuel:Plasma pauvre en plaquettes:Numérique:Technique chromogénique
fr-BE French (Belgium) Protéase de clivage du Facteur von Willebrand Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Chromogénique
Synonyms: Fvw Mesuré/normal
it-IT Italian (Italy) von Willebrand, proteasi di taglio fattore effettivo/normale:RelCCnc:Pt:PPP:Qn:Cromo
Synonyms: Concentrazione Catalitica Relativa Cromogenico (Enzima) Fattore di von Willebrand (vWf) Plasma povero di piastrine Proteasi di taglio del fattore di von Willebrand Punto nel tempo (episodio) Studio di coagulazione
nl-NL Dutch (Netherlands) von Willebrand-factor cleaving protease gemeten/normaal:relatieve enzymatische activiteit/normaal:moment:plaatjesarm plasma:kwantitatief:chromogeen
Synonyms: coagulatiemethode gemeten/normaal
pt-BR Portuguese (Brazil) fator de von Willebrand clivagem da protease verdadeiro/normal:RelCCnc:Pt:PPPQ:Qn:Método Cromogênico (enzima)
Synonyms: ; vWF Cp; ADAMTS13; vWCP; VWF-cp; VWFCP; vWf; Nor; RlCCnc; Point in time; Random; Platelet poor plasma; Plas; Quantitative; QNT; Quant; Quan; Chro; Enzymatic assay; Chromogenic assay; ENZY; Act/Nor; Vonwillebrand; Von will; PR; Control; Fac; Fact; COAGULATION
ru-RU Russian (Russian Federation) von Willebrand фактор (vWf) расщепляющая протеаза актуальный/нормальный:ОтнКаталКонц:ТчкВрм:ОПП:Колич:Хромо
Synonyms: Количественный Обеднённая пластинками плазма;Бедная тромбоцитами плазма Относительная каталитическая концентрация Точка во времени;Момент Хромогенный (Фермент)
tr-TR Turkish (Turkey) von Willebrand faktörü parçalıyıcı proteaz gerçek/normal:GörKtlKons:Zmlı:TFkP:Kant:Kromo
zh-CN Chinese (China) von Willebrand 因子裂解蛋白酶 实际的/正常的:相对催化浓度:时间点:贫血小板血浆:定量型:凝血因子酶学测定法
Synonyms: von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）裂解蛋白酶;ADAMTS13;von Willebrand 因子裂解蛋白酶（von Willebrand Factor Cleaving Protease，VWF-cp）;von Willebrand 因子裂解酶;vWCP;vWf 因子裂解蛋白酶;vWf 因子裂解酶;vWf 裂解酶;VWFCP;VWF-cp;血管性血友病因子裂解蛋白酶;血管性血友病因子裂解酶 乏血小板血浆;Platelet poor plasma;PPP 冯·威勒布兰德 冯威勒布兰德 冯威勒布兰德氏 凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程 凝血因子发色测定方法;凝血因子发色测定法;凝血因子酶学测定方法;发色法;发色测定方法;发色测定法;显色法;显色测定方法;显色测定法;酶学法;酶学测定方法;酶学测定法;酶法 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 因素 实测值 实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值 实测的 实际值 对照 对照标准 对照物 对照的 时刻;随机;随意;瞬间 朊酶 正常的 系数 蛋白质酵素

Example Units

Unit Source
% Example UCUM Units
% REGENSTRIEF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53622-7