53622-7

von Willebrand factor (vWf) cleaving protease actual/normal in Platelet poor plasma by Chromogenic method

Active

Part Description

LP32458-9 von Willebrand factor cleaving protease
von Willebrand factor (vWF) cleaving protease, or ADAMTS13, is a metalloprotease that cleaves vWF and thereby limits platelet aggregation and formation of microthrombi. vWF cleaving protease inhibitors can decrease the protease activity and/or more rapidly remove the enzyme from the circulation. Such inhibitors are one cause of thrombotic thrombocytopenic purpura (TTP), a disorder characterized by thrombocytopenia, anemia, fever, and neurologic and renal abnormalities. Idiopathic TTP is often due to anti-ADAMTS13 autoantibodies, while inherited TTP is an autosomal recessive disorder due to mutations in the ADAMTS13 gene that lead to impaired protease function. Work-up of patients with TTP can include vWF cleaving protease activity and, if that activity is low, inhibitor screen followed by quantification. PMID: 18756543 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: von Willebrand factor cleaving protease actual/normal:RelCCnc:Pt:PPP:Qn:Chromo
Long Common Name: von Willebrand factor (vWf) cleaving protease actual/normal in Platelet poor plasma by Chromogenic method
Short Name: vWF Cp Act/Nor PPP Chro
Display Name: vWf cleaving protease actual/normal Chromogenic method (PPP) [Rel catalytic activity/Vol]
Consumer Name Alpha Get Info: vWf cleaving protease actual/normal, Blood

Part Model Get Info

Component
von Willebrand factor cleaving protease actual/normal
LP229927-1
- Analyte
  von Willebrand factor cleaving protease actual/normal
  LP229927-1
  - Component Numerator
    von Willebrand factor cleaving protease actual/normal
    LP229927-1
    - Component Numerator Core
      von Willebrand factor cleaving protease
      LP32458-9
    - Component Numerator Core Suffix
      actual/normal
      LP29333-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
RelCCnc
LP31739-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
PPP
LP7494-0
- System Core
  PPP
  LP7494-0
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Chromo
LP6256-4

Basic Attributes

Class: COAG
Type: Laboratory
First Released: Version 2.26
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 3826

Language Variants Get Info

Tag	Language	Translation
ar-JO	Arabic (Jordan)	نسبة عامل فون ويلبراند المحلل للبروتياز الفعلي / الطبيعي في البلازما الفقيرة بالصفيحات الدموية ( بتقنية التلوين الكروموجيني )
cs-CZ	Czech (Czechia)	von Willebrandův faktor štěpící proteáza aktuální/normální:Relativní katalytická koncentrace:Časový bod:Plazma chudá na trombocyty:Kvantitativní:Chromogenní (enzymatický) test
de-AT	German (Austria)	Synonyms: ADAMTS 13 Aktivität
el-GR	Greek (Greece)	πρωτεάση διάσπασης παράγοντα Von Willebrand πραγματικό/φυσιολογικό:RelCCnc:Pt:PPP:Qn:Chromo Synonyms: Chromo COAG PPP Pt Qn RelCCnc παράγοντας Von Willebrand πραγματικό/φυσιολογικό πρωτεάση διάσπασης παράγοντα Von Willebrand
es-ES	Spanish (Spain)	Proteasa divisora del Factor de von Willebrand actual/normal:Concentración catalítica relativa:Punto temporal:Plasma pobre en plaquetas:Qn:Cromogénico ( Enzima) Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	proteasa de escisión del factor von Willebrand real / normal:Concentración catalítica relativa:Punto temporal:Plasma pobre en plaquetas:Cuantitativo:Cromogénico (enzima)
fr-CA	French (Canada)	Protéase clivage du Facteur von Willebrand, Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Chromogénique
fr-FR	French (France)	Facteur Willebrand protéase patient/témoin:Activité catalytique relative:Ponctuel:Plasma pauvre en plaquettes:Numérique:Technique chromogénique
fr-BE	French (Belgium)	Protéase de clivage du Facteur von Willebrand Mesuré/normal:Concentration catalytique relative:Temps ponctuel:Plasma pauvre en plaquettes:Quantitatif:Chromogénique Synonyms: Fvw Mesuré/normal
it-IT	Italian (Italy)	von Willebrand, proteasi di taglio fattore effettivo/normale:RelCCnc:Pt:PPP:Qn:Cromo Synonyms: Concentrazione Catalitica Relativa Cromogenico (Enzima) Fattore di von Willebrand (vWf) Plasma povero di piastrine Proteasi di taglio del fattore di von Willebrand Punto nel tempo (episodio) Studio di coagulazione
nl-NL	Dutch (Netherlands)	von Willebrand-factor cleaving protease gemeten/normaal:relatieve enzymatische activiteit/normaal:moment:plaatjesarm plasma:kwantitatief:chromogeen Synonyms: coagulatiemethode gemeten/normaal
pl-PL	Polish (Poland)	Proteaza rozkładająca czynnik von Willebranda badane/prawidłowe:względne stężenie katalityczne:punkt w czasie:osocze ubogopłytkowe:ilościowy:metoda z substratem chromogennym Synonyms: ADAMTS13 Czynnik von Willebranda (vWf) PPP
pt-BR	Portuguese (Brazil)	fator de von Willebrand clivagem da protease verdadeiro/normal:RelCCnc:Pt:PPPQ:Qn:Método Cromogênico (enzima) Synonyms: ; vWF Cp; ADAMTS13; vWCP; VWF-cp; VWFCP; vWf; Nor; RlCCnc; Point in time; Random; Platelet poor plasma; Plas; Quantitative; QNT; Quant; Quan; Chro; Enzymatic assay; Chromogenic assay; ENZY; Act/Nor; Vonwillebrand; Von will; PR; Control; Fac; Fact; COAGULATION
ru-RU	Russian (Russian Federation)	von Willebrand фактор (vWf) расщепляющая протеаза актуальный/нормальный:ОтнКаталКонц:ТчкВрм:ОПП:Колич:Хромо Synonyms: Количественный Обеднённая пластинками плазма;Бедная тромбоцитами плазма Относительная каталитическая концентрация Точка во времени;Момент Хромогенный (Фермент)
tr-TR	Turkish (Turkey)	von Willebrand faktörü parçalıyıcı proteaz gerçek/normal:GörKtlKons:Zmlı:TFkP:Kant:Kromo
zh-CN	Chinese (China)	von Willebrand 因子裂解蛋白酶实际的/正常的:相对催化浓度:时间点:贫血小板血浆:定量型:凝血因子酶学测定法 Synonyms: von Willebrand von Willebrand 因子（von Willebrand Factor，vWf）;vWf;vWf 因子;血管性假血友病因子;血管性血友病因子 von Willebrand 因子（vWf 因子、血管性假血友病因子、血管性血友病因子）裂解蛋白酶;ADAMTS13;von Willebrand 因子裂解蛋白酶（von Willebrand Factor Cleaving Protease，VWF-cp）;von Willebrand 因子裂解酶;vWCP;vWf 因子裂解蛋白酶;vWf 因子裂解酶;vWf 裂解酶;VWFCP;VWF-cp;血管性血友病因子裂解蛋白酶;血管性血友病因子裂解酶乏血小板血浆;Platelet poor plasma;PPP 冯·威勒布兰德冯威勒布兰德冯威勒布兰德氏凝血功能;凝血功能试验;凝血过程;血液凝固;血液凝固功能;血液凝固过程凝血因子发色测定方法;凝血因子发色测定法;凝血因子酶学测定方法;发色法;发色测定方法;发色测定法;显色法;显色测定方法;显色测定法;酶学法;酶学测定方法;酶学测定法;酶法可用数量表示的;定量性;数值型;数量型;连续数值型标尺因素实测值实测值/正常值;实际/正常;实际值/正常值;实际测定值/正常值实测的实际值对照对照标准对照物对照的时刻;随机;随意;瞬间朊酶正常的系数蛋白质酵素

Example Units

Unit	Source
%	Example UCUM Units
%	REGENSTRIEF

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.