53707-6

CV2 IgG Ab [Presence] in Cerebrospinal Fluid by Immunoblot

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Term Description

CV2 IgG in cerebrospinal fluid (CFS) can be detected by western blot assays and is highly recommended for evaluating patients with subacute unexplained basal ganglionic disorders (chorea/Parkinsonism hemi-ballismus), cranial neuropathies (particularly loss of vision, smell or taste), myelopathies, and radiculoplexopathies. CV2-IgG is also a sensitive confirmatory marker for thymoma and lung carcinoma (SCLC-small cell lung carcinomas).

Part Description

LP32718-6 CV2
CV2 (CRMP5) antibody binds to cytoplasm and cell processes of a subpopulation of oligodendrocytes in the white matter and targets 66 kDa protein known as CRMP5.
It is ofen found in association with small cell lung carcinoma. CV2 autoimmune response can also be found in cerebellar ataxia, encephalomyelitis, limbic encephalitis, sensory and sensorimotor neuropathy, autonomic neuropathy, and chorea. CV2 autoantibodies are also present in patients with rapidly progressive dementia, and are used to monitor treatment in some cases. Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: CV2 Ab.IgG:PrThr:Pt:CSF:Ord:IB
Long Common Name: CV2 IgG Ab [Presence] in Cerebrospinal Fluid by Immunoblot
Short Name: CV2 IgG CSF Ql IB
Display Name: CV2 IgG IB Ql (CSF)
Consumer Name Alpha Get Info: CV2 IgG antibody, Spinal fluid

Part Model Get Info

Component
CV2 Ab.IgG
LP157736-2
- Analyte
  CV2 Ab.IgG
  LP157736-2
  - Component Numerator
    CV2 Ab.IgG
    LP157736-2
    - Component Numerator Core
      CV2
      LP32718-6
    - Component Numerator Core Suffix
      Ab.IgG
      LP32401-9
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
CSF
LP7156-5
- System Core
  CSF
  LP7156-5
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IB
LP6320-8

Basic Attributes

Class: SERO
Type: Laboratory
First Released: Version 2.26
Last Updated: Version 2.83 (MIN)
Change Reason: Collapsin response mediator protein 5 (CRMP5) Ab is also known as CV2 Ab. Changed component from Collapsin response mediator protein 5 Ab.IgG to harmonize with existing terms.; The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both
Common Test Rank Get Info: 11095

Member of these Panels

LOINC	Long Common Name
94712-7	Movement disorder autoimmune Ab panel - Cerebrospinal Fluid
94353-0	Myelopathy autoimmune Ab panel - Cerebrospinal Fluid

Member of these Groups Get Info

LOINC Group	Group Name
LG51752-0	CV2 Ab.IgG\|PrThr\|Pt\|CSF

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	CV2 IgG:Přítomnost nebo práh:Časový bod:Mozkomíšní mok:Ordinální:Imunoblot
de-DE	German (Germany)	CV2 Ak.IgG:Nachweis oder Schwellenwert:Zeitpunkt:Liquor:Ordinal:Immunoblot Synonyms: Zerebrospinalflüssigkeit
el-GR	Greek (Greece)	CV2 Αντισώματα IgG:PrThr:Pt:ΕΝΥ:Ord:IB Synonyms: CV2 IB Ord PrThr Pt SERO Ανοσοσφαιρίνη G Αντίσωμα Αντισώματα IgG ΕΝΥ
es-ES	Spanish (Spain)	CV2 IgG:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Inmunoblot (IB)
es-MX	Spanish (Mexico)	CV2 Ab.IgG:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunotransferencia
et-EE	Estonian (Estonia)	CV2 antikehad.IgG:PrThr:Pt:CSF:Ord:IB Synonyms: Immuunglobuliin G Järgarvuline Juhuslik Liikvor
fr-CA	French (Canada)	CV2, IgG:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Immunoblot
fr-FR	French (France)	CV2 Ac IgG:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoblot
fr-BE	French (Belgium)	CV2 Anticorps. IgG:PrThr:Temps ponctuel:LCR:Ordinal:Immunoblot Synonyms: Anticorps
it-IT	Italian (Italy)	CV2 Ab.IgG:PrThr:Pt:LCS:Ord:IB Synonyms: anticorpi IgG anticorpo Immunoblot (IB) Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL	Dutch (Netherlands)	CV2 As.IgG:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoblotting Synonyms: antistof; antilichaam IB
pt-BR	Portuguese (Brazil)	Colapsina proteína mediador de resposta 5 Ac.IgG:ACnc:Pt:LCR:Ord:Imunoblot Synonyms: ; Prot; PR; Immune globulin G; Immunoglobulin G; CRMP-5; Arbitrary concentration; Point in time; Random; Cerebral spinal fluid; Spinal Fluid; Cerebrospinal Fl; Spinal Flu; Spinal Fld; Ql; Ordinal; QL; Qualitative; Qual; Screen; Western blot; WB; Immune blot; Immunobl; Blt; WBLOT; West blt; West blot; RIBA; Immunoblot; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU	Russian (Russian Federation)	CV2 Ат.IgG:PrThr:ТчкВрм:ЦСЖ:Пор:ИБ Synonyms: Антитело Иммуноблот (ИБ) Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR	Turkish (Turkey)	CV2 Ab.IgG:MevcEşik:Zmlı:BOS:Srl:IB Synonyms: Ak Ak.IgG Mevcut
uk-UA	Ukrainian (Ukraine)	CV2 Антитіла.IgG:Наявність або Поріг:МоментЧасу:Спинномозкова рідина:Порядково:Імуноблот Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Autoantibodies; Autoantibody; Blt; Cerebral spinal fluid; Cerebrospinal Fl; Collapsin response mediator protein 5; Collapsin response mediator protein 5 Ab; Collapsin response mediator protein 5 Ab.IgG; CRMP5; CRMP-5; Immune blot; Immune globulin G; Immunobl; Immunoblot; Immunoglobulin G; Ordinal; Point in time; POP66; PR; QL; Qual; Qualitative; Random; RIBA; Screen; Serology; Spinal Fl; Spinal Fld; Spinal Flu; Spinal Fluid; ULIP; WB; WBLOT; West blot; West blt; Western blot
zh-CN	Chinese (China)	CV2 抗体.IgG:存在情况或阈值:时间点:脑脊液:序数型:免疫印迹法 Synonyms: Ab.IgG;IgG;抗体 IgG Ab;自身抗体 CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 CV2 Ab paraneoplastic oligodendrocyte protein of 66 kDa;66 kDa 副肿瘤性少突胶质细胞蛋白;POP66;ULIP;Unc-33-like phosphoprotein;Unc-33-样磷蛋白;Collapsin response mediator protein 5;CRMP5;坍塌反应调节蛋白 5;脑衰蛋白响应调解蛋白 5;塌陷反应介导蛋白 5;脑衰反应调节蛋白 5;脑衰蛋白响应调解蛋白 5;small cell lung carcinoma;SCLC;小细依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 免疫球蛋白 G 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间脊液脊髓液脑脊液（Cerebral spinal fluid，CSF）脑脊髓液血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.