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Term Description

PCA-1 antibody is rarely found in patients with neurologic diseases without breast or gynecologic cancer. Conversely, it is rarely found in patients with breast or gynecologic cancer without neurologic dysfunction. Paraneoplastic cerebellar degeneration is associated with breast or gynecological (ovarian, fallopian, endometrial) tumors, and less commonly with lung (SCLC -small cell lung cancer) or Hodgkin lymphoma. More than 50% of seropositive patients present with subacute cerbellar ataxia and approximately 5% with sensorimotor or motor neuropathy. Information from http://www.clinlabnavigator.com accessed 2008 14 02.

Part Description

LP71327-8   Purkinje cell cytoplasmic type 1
Purkinje cell cytoplasmic antibody type 1 (PCA-1) (or anti-Yo) is detected in patients with gynecological or breast adenocarcinoma who present with paraneoplastic cerebellar degeneration. PMID: 1407575 PCA-1 autoimmunity most commonly affects the cerebellum, but the spectrum of neurological symptoms and presentations is broad. Non-cerebellar tissue in the central, peripheral and autonomic nervous systems may also be involved. Neurological outcomes are usually poor, even when cancer remission is achieved. PMID: 21670387 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Purkinje cell cytoplasmic type 1 Ab:Titr:Pt:Ser:SemiQn:
Long Common Name
PCA-1 Ab [Titer] in Serum
Short Name
PCA-1 Ab Titr Ser
Display Name
PCA-1 Ab (S) [Titer]
Consumer Name Alpha Get Info
PCA-1 antibody, Blood

Part Model Get Info

  • Component
    Purkinje cell cytoplasmic type 1 Ab
    LP70987-0
    • Analyte
      Purkinje cell cytoplasmic type 1 Ab
      LP70987-0
      • Component Numerator
        Purkinje cell cytoplasmic type 1 Ab
        LP70987-0
        • Component Numerator Core
          Purkinje cell cytoplasmic type 1
          LP71327-8
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    Titr
    LP6881-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    SemiQn
    LP436123-6
  • Method
    NULL
     

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.75 (MAJ)
Change Reason
Changed "Purkinje cells" in Component to the more common name, "Purkinje cell cytoplasmic".
Order vs. Observation
Both
Common Test Rank Get Info
2583

Member of these Groups Get Info

LOINC GroupGroup Name
LG50989-9Purkinje cell cytoplasmic type 1 Ab|Titr|Pt|ANYBldSerPl

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)PCA-1 Ab:Arbitrární koncentrace (titr):Časový bod:Sérum:Semikvantitativní:
el-GRGreek (Greece)Κύτταρο Purkinje κυτταροπλασματικού τύπου 1 Αντίσωμα:Titr:Pt:Ορός:Ημιποσοτική:
Synonyms: Pt SERO Titr Type Αντίσωμα Ημιποσοτική Κύτταρο Purkinje κυτταροπλασματικού τύπου 1 Κυτταροπλασματικό Ορός
es-ESSpanish (Spain)Células de Purkinje tipo 1 Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Semicuantitativo:
Synonyms: Semicuantitativo
es-MXSpanish (Mexico)Ab citoplasmático tipo 1 de células de Purkinje:Título:Punto temporal:Suero:Cuantitativo:
fr-CAFrench (Canada)Cellules de Purkinje cytoplasmique type 1, Ac:Titre:Temps ponctuel:Sérum:SemiQn:
fr-FRFrench (France)APCA-1 Ac:Titre:Ponctuel:Sérum:Semi-Quantitatif:
it-ITItalian (Italy)Cellule di Purkinje tipo 1 Ab:Titr:Pt:Siero:SemiQn:
Synonyms: anticorpo Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo
nl-NLDutch (Netherlands)purkinjecellen type 1 As:titer:moment:serum:semikwantitatief:
Synonyms: antistof; antilichaam soort
pl-PLPolish (Poland)Cytoplazmatyczne typu 1 komórek Purkinjego Ab:miano:punkt w czasie:surowica:półilościowy:
Synonyms: PCA-1 Przeciwciała do PCA-1
pt-BRPortuguese (Brazil)Células Purkinje tipo 1 Ac:Título:Pt:Soro:Qn:
Synonyms: ; Purkinje Cells 1; Cell; Cellularity; Dilution factor; Titer; Titre; Ttr; Titered; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; I; Serology
zh-CNChinese (China)浦肯雅细胞胞浆 1 型 抗体:滴定度:时间点:血清:半定量型:
Synonyms: Ⅰ Ab;自身抗体 I 型 效价;滴定浓度;滴定率;滴定量;滴度;稀释倍数;稀释因子;稀释系数 时刻;随机;随意;瞬间 浦肯雅细胞胞浆（细胞浆、细胞质、胞质） 1 型;浦肯雅细胞 1 型;1 型 Purkinje 细胞;1 型朴金耶细胞;1 型浦肯雅细胞;1 型浦金埃细胞;Purkinje 细胞 1 型;朴金耶细胞 1 型;浦金埃细胞 1 型 细胞浆的;细胞质;细胞质的;胞浆;胞浆的 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

UnitSource
titerREGENSTRIEF
{titer}Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53717-5