LOINC
Version 2.73

5381-9Thyroglobulin Ab [Titer] in Serum by Latex agglutinationActive

Part Descriptions

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Thyroglobulin (Wikipedia)

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. [PMID:9543128] Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Thyroglobulin (Wikipedia)

LP39996-1   Thyroglobulin Ab
Circulating immunoglobulins directed against thyroglobulin are commonly present in patients with autoimmune (Hashimoto) thyroiditis and, to a lesser extent, Graves disease. Thyroglobulin is a 660-kd protein precursor of thyroid hormones. Thyroglobulin antibodies are present in the sera of approximately 70% of patients with autoimmune thyroiditis. The principal use of the test is to confirm that a patient's diffuse goiter and/or hypothyroidism is due to autoimmune thyroiditis. The test may also help distinguish Graves disease from toxic nodular goiter. Although thyroglobulin antibodies are present less often than thyroid microsomal antibodies (eg, thyroid peroxidase antibodies, anti-TPO) in patients with autoimmune thyroid diseases, screening fro both immunoglobulins increases diagnostic sensitivity. Thyroglobulin antibodies may be detected in individuals without clinically significant thyroid disease. They do not define the patient's thyroid functional status. Source: Quest Diagnostics Inc., Thyroglobulin antibodies

Fully-Specified Name

Component
Thyroglobulin Ab
Property
Titr
Time
Pt
System
Ser
Scale
Qn
Method
LA

Additional Names

Short Name
Thyroglob Ab Titr Ser LA
Display Name
Thyroglobulin Ab LA (S) [Titer]
Consumer Name Alpha
Thyroglobulin antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Order vs. Observation
Both
Common US Lab Results Rank
16347

Reference Information

Type Source Reference
Webcontent Lab Tests Online®Copyright Copyright © 2021 Lab Tests Online. All rights reserved. Thyroid Antibodies

Member of these Groups

LG15249-2 Thyroglobulin Ab|Titr|Pt|ANYBldSerPl

Language Variants Get Info

zh-CNChinese (China)
甲状腺球蛋白 抗体:滴定度:时间点:血清:定量型:胶乳凝集试验法
nl-NLDutch (Netherlands)
thyreoglobuline As:titer:moment:serum:kwantitatief:latexagglutinatie
et-EEEstonian (Estonia)
Türeoglobuliin antikehad:Titr:Pt:S:Qn:LA
fr-BEFrench (Belgium)
Thyroglobuline Ac:Titre:Temps ponctuel:Sérum:Quantitatif:Agglutination au latex
fr-CAFrench (Canada)
Thyroglobuline , Ac:Titre:Temps ponctuel:Sérum:Quantitatif:Agglutination au latex
fr-FRFrench (France)
Thyroglobuline anticorps:Titre:Ponctuel:Sérum:Numérique:Agglutination latex
de-DEGerman (Germany)
Thyreoglobulin Ak:Titer:Zeitpunkt:Serum:Quantitativ:Latexagglutination
el-GRGreek (Greece)
Θυρεοσφαιρίνη Αντίσωμα:Τίτλος:Χρονική στιγμή:Ορός:Ποσοτική:Μέθοδος συγκόλλησης ανοσοσφαιριδίων latex
it-ITItalian (Italy)
Tireoglobulina Ab:Titr:Pt:Siero:Qn:LA
ko-KRKorean (Korea, Republic of)
갑상샘글로불린 항체:역가:검사시점:혈청:정량:라텍스 응집
pt-BRPortuguese (Brazil)
Tireoglobulina Ac:Título:Pt:Soro:Qn:Aglutinação em látex
ru-RURussian (Russian Federation)
Тиреоглобулин Ат:Титр:ТчкВрм:Сыв:Колич:ЛА
es-ARSpanish (Argentina)
[anticuerpo anti - ] tiroglobulina [Ac]:factor de dilución (titulación):punto en el tiempo:suero:cuantitativo:aglutinación de látex
es-MXSpanish (Mexico)
Tiroglobulina Ab:Título:Punto temporal:Suero:Cuantitativo:Aglutinación de látex
es-ESSpanish (Spain)
Tiroglobulina Anticuerpos:Titulo / Factor de dilución:Punto temporal:Suero:Qn:Aglutinación de latex
tr-TRTurkish (Turkey)
Tiroglobulin Ab:Titr:Zmlı:Ser:Kant:LA
uk-UAUkraine (Ukrainian)
Тиреоглобулін, Антитіла:Титр:МоментЧасу:Сироватка:Кількісно:Латекс аглютинація

Example Units

Unit Source
{titer} Example UCUM Units
titer REGENSTRIEF

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5381-9