Version 2.80

Part Descriptions

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a protein produced by and used entirely within the thyroid gland. Thyroglobulin is used by the thyroid gland to produce the thyroid hormones thyroxine (T4) and triiodothyronine (T3). Thyroglobulin is stored in the thyroid in follicle cysts surrounded by colloid cells. Via a reaction with the enzyme thyroperoxidase, iodine is covalently bound to tyrosine residues in thyroglobulin molecules, forming monoiodotyrosine (MIT) and diiodotyrosine (DIT). Thyroxine is produced by linking two moieties of DIT. Combining one particle of MIT and one particle of DIT produces triiodothyronine. Proteases in lysosomes digest iodinated thyroglobulin, releasing T3 and T4. Thyroglobulin levels in the blood can be used as a tumor marker for certain kinds of thyroid cancer. Thyroglobulin levels in the blood can also be elevated in cases of Graves Disease. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia , Thyroglobulin (Wikipedia)

LP14697-4   Thyroglobulin
Thyroglobulin (Tg) is a glycoprotein homodimer produced by the thyroid gland. It is important in the synthesis of thyroxine and triiodothyronine, and is where the inactive forms of thyroid hormone and iodine are stored. Mutations in the Tg gene cause thyroid dyshormonogenesis resulting in goiter, and can be associated with moderate to severe congenital hypothyroidism. Polymorphisms in the Tg gene are associated with susceptibility to autoimmune thyroid diseases such as Graves disease or Hashimoto thyroiditis. [NCBI Gene ID:7038] Tg is an established tumor marker used in the diagnosis of differentiated thyroid carcinoma. PMID: 9543128 Source: Regenstrief LOINC

LP39996-1   Thyroglobulin Ab
Circulating immunoglobulins directed against thyroglobulin are commonly present in patients with autoimmune (Hashimoto) thyroiditis and, to a lesser extent, Graves disease. Thyroglobulin is a 660-kd protein precursor of thyroid hormones. Thyroglobulin antibodies are present in the sera of approximately 70% of patients with autoimmune thyroiditis. The principal use of the test is to confirm that a patient's diffuse goiter and/or hypothyroidism is due to autoimmune thyroiditis. The test may also help distinguish Graves disease from toxic nodular goiter. Although thyroglobulin antibodies are present less often than thyroid microsomal antibodies (eg, thyroid peroxidase antibodies, anti-TPO) in patients with autoimmune thyroid diseases, screening fro both immunoglobulins increases diagnostic sensitivity. Thyroglobulin antibodies may be detected in individuals without clinically significant thyroid disease. They do not define the patient's thyroid functional status. Source: Quest Diagnostics Inc. , Thyroglobulin antibodies

Fully-Specified Name

Component
Thyroglobulin Ab
Property
ACnc
Time
Pt
System
Lymph node.FNA
Scale
Qn
Method

Additional Names

Long Common Name
Thyroglobulin Ab [Units/volume] in Lymph node fine needle aspirate
Short Name
Thyroglob Ab LN FNA-aCnc
Display Name
Thyroglobulin Ab Qn (Lymph node fine needle aspirate)
Consumer Name Alpha Get Info
Thyroglobulin antibody, Lymph node fine needle aspirate

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Θυρεοσφαιρίνη Αντίσωμα:ACnc:Pt:Λεμφαδένας.αναρρόφηση δια λεπτής βελόνης:Qn:
Synonyms: ACnc Θυρεοσφαιρίνη
es-ES Spanish (Spain) Tiroglobulina Anticuerpos:Concentración arbitraria:Punto temporal:Aspiración con aguja fina (biopsia) de los ganglios linfáticos:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Tiroglobulina Ab:Concentración arbitraria:Punto temporal:FNA de ganglio linfático:Cuantitativo:
fr-CA French (Canada) Thyroglobuline, Ac:Concentration arbitraire:Temps ponctuel:Ganglion lymphatique.Aspiration à l'aiguille fine:Quantitatif:
fr-FR French (France) Thyroglobuline anticorps:Arbitraire/Volume:Ponctuel:Ganglion lymphatique prélèvement à l'aiguille fine:Numérique:
fr-BE French (Belgium) Thyroglobuline Ac:Concentration arbitraire:Temps ponctuel:Ganglion lymphatique.Aspiration à l'aiguille fine:Quantitatif:
Synonyms: Anticorps hTG
it-IT Italian (Italy) Tireoglobulina Ab:ACnc:Pt:Linfonodo.FNA:Qn:
Synonyms: anticorpo Concentrazione Arbitraria Linfonodo Agoaspirato Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) thyreoglobuline As:eenheid/volume:moment:lymfeklier.FNA:kwantitatief:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Tireoglobulina Ac:ACnc:Pt:Nódulo linfático.punção por agulha fina:Qn:
Synonyms: AntiTiroglob; TgAcs; Tiroglob; Thyglobulin; Thyroglbn; Tg; Arbitrary concentration; Point in time; Random; LN FNA; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Fine needle; Serology
ru-RU Russian (Russian Federation) Тиреоглобулин Ат:ПроизвКонц:ТчкВрм:Лимфатический узел.АБТИ:Колич:
Synonyms: Антитело Количественный Лимфатический узел.аспирационная биопсия тонкой иглой Произвольная концентрация Точка во времени;Момент
tr-TR Turkish (Turkey) Tiroglobulin Ab:SçKons:Zmlı:Lenf nodu.İBB:Kant:
zh-CN Chinese (China) 甲状腺球蛋白 抗体:任意型浓度:时间点:淋巴结.细针吸出物:定量型:
Synonyms: Ab;自身抗体 FNA TG;甲状球蛋白;甲状腺球朊;甲状腺球蛋白（Thyroglobulin，TG，Tg）;甲状腺球蛋白特异性 TgAbs 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 抗甲状腺球蛋白 时刻;随机;随意;瞬间 淋巴结.FNA;淋巴结.细针抽出物;淋巴结细针吸出物;淋巴结细针抽出物 甲状腺球蛋白 Ab 细针 细针抽出物 细针抽吸物 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
[IU]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53921-3