Version 2.80

Part Description

LP71684-2   Centromere protein B Ab
Major centromere autoantigen B, also known as centromere protein B or CENP-B, is encoded by the CENPB gene located on chromosome 20p13. CENP-B interacts with chromosomal centromeric heterochromatin and binds to a specific subset of alphoid satellite DNA, called the CENP-B box. [UniProt: P07199] CENP-B plays a direct role in stablizing CENP-C, which is a kinetochore assembly nucleator, and recruiting CENP-A, which marks and maintains centromere position. Chromosomes that have centromeres without bound CENP-B, including the human Y chromosome, are more likely to missegregate at much higher rates than chromosomes with CENP-B containing centromeres. PMID: 25942623 Autoantibodies to both CENP-A and CENP-B are markers for scleroderma and other rheumatic diseases. PMID: 17210244 Source: Regenstrief LOINC , UniProt: P07199

Fully-Specified Name

Component
Centromere protein B Ab
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Long Common Name
Centromere protein B Ab [Units/volume] in Serum
Short Name
Centromere B Ab Ser-aCnc
Display Name
Centromere protein B Ab Qn (S)
Consumer Name Alpha Get Info
Centromere Protein B antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.26
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
1998

Member of these Groups Get Info

LOINC Group Group Name
LG21821-0 Centromere protein B Ab|ACnc|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: CENP-B-AK
de-DE German (Germany) Zentromerprotein B Ak:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:
Synonyms: CENP
el-GR Greek (Greece) Πρωτεΐνη κεντρομερούς Β Αντίσωμα:ACnc:Pt:Ορός:Qn:
Synonyms: ACnc B Κεντρομερίδιο Πρωτεΐνη Πρωτεΐνη κεντρομερούς Β
es-ES Spanish (Spain) Proteína B del centrómero Anticuerpos:Concentración arbitraria:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Centrómero de proteína B Ab:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:
et-EE Estonian (Estonia) Tsentromeer B vastased antikehad:Acnc:Pt:S:Qn:
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Centromère protéine B, Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
fr-FR French (France) Centromère protéine B anticorps:Arbitraire/Volume:Ponctuel:Sérum:Numérique:
fr-BE French (Belgium) Centromère. Protéine B Ac:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
Synonyms: Anticorps
it-IT Italian (Italy) Centromero, proteina B Ab:ACnc:Pt:Siero:Qn:
Synonyms: anticorpo Concentrazione Arbitraria Proteina B del centromero Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) centromeereiwit B As:eenheid/volume:moment:serum:kwantitatief:
Synonyms: antistof; antilichaam
pt-BR Portuguese (Brazil) Proteína B do Centrômero Ac:ACnc:Pt:Soro:Qn:
Synonyms: ; Prot; PR; Centromere B; CENP-B; CENPB; CRST syndrome; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) Центромерный протеин B Ат:ПроизвКонц:ТчкВрм:Сыв:Колич:
Synonyms: Антитело Белок Количественный Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Sentromer protein B Ab:SçKons:Zmlı:Ser:Kant:
uk-UA Ukrainian (Ukraine) Центромерний білок В, Антитіла:Довільна Концентрація:МоментЧасу:Сироватка:Кількісно:
Synonyms: ABS; Aby; Antby; Anti; Antibodies; Antibody; Arbitrary concentration; Autoantibodies; Autoantibody; Cen; CENP B; CENPB; CENP-B; Centromere B; CRST syndrome; Major centromere autoantigen B; Point in time; PR; Prot; QNT; Quan; Quant; Quantitative; Random; Serology; Serum; SR; UniversalLabOrders
zh-CN Chinese (China) 着丝点蛋白 B 抗体:任意型浓度:时间点:血清:定量型:
Synonyms: Ab;自身抗体 B 型 B型抗体 CRST 综合征;着丝粒;动粒 PR;Prot;成分 - 化学 - 蛋白质类;蛋白;朊;蛋白质类;蛋白质类物质 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 着丝粒蛋白 B;动粒蛋白 B 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目（非微生物学）;血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验（非微生物学）;血清学试验类 (非微生物学);血清类

Example Units

Unit Source
[arb'U];[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=53982-5