54288-6

Guanidinoacetate [Moles/volume] in Amniotic fluid

Active

Part Description

LP30825-1 Guanidinoacetate
Guanidinoacetate is the immediate precursor of creatine. Guanidinoacetate methyltransferase (GAMT) is the enzyme responsible for converting guanidinoacetate to creatine, and GAMT deficiency causes is a rare, autosomal recessive disorder whose manifestations include seizures, developmental delay, learning difficulties, and autism. Motor function is relatively spared. GAMT deficiency leads to elevated levels of plasma and urine guanidinoacetate, and low plasma creatine and creatinine levels. Elevated levels of guanidinoacetate in the brain are one cause of seizures in patients with GAMT deficiency. The primary treatment is creatine supplementation, which may be combined with ornithine supplementation and arginine restriction. Early diagnosis and treatment may prevent organ damage and preserve cognitive function. If the diagnosis does not occur early and brain damage has already occurred at the time of diagnosis, creatine supplementation can still help control seizures and improve quality of life. PMID: 28119378 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Guanidinoacetate:SCnc:Pt:Amnio fld:Qn:
Long Common Name: Guanidinoacetate [Moles/volume] in Amniotic fluid
Short Name: Guanidinoacetate Amn-sCnc
Display Name: Guanidinoacetate (Amn fld) [Moles/Vol]
Consumer Name Alpha Get Info: Guanidinoacetate, Amniotic fluid

Part Model Get Info

Component
Guanidinoacetate
LP30825-1
- Analyte
  Guanidinoacetate
  LP30825-1
  - Component Numerator
    Guanidinoacetate
    LP30825-1
    - Component Numerator Core
      Guanidinoacetate
      LP30825-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
SCnc
LP6860-3
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Amnio fld
LP7000-5
- System Core
  Amnio fld
  LP7000-5
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.27
Last Updated: Version 2.70 (MIN)
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Guanidinacetát:Látková koncentrace:Časový bod:Amniová tekutina:Kvantitativní:
el-GR	Greek (Greece)	Γουανιδινοξικό:SCnc:Pt:Αμνιακό υγρό:Qn: Synonyms: CHEM Pt Qn SCnc Αμνιακό υγρό Γουανιδινοξικό
es-ES	Spanish (Spain)	Guanidinoacetato:Concentración de sustancia:Punto temporal:Fluido Ammiótico:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Guanidinoacetato:Concentración de sustancias:Punto temporal:Líquido amniótico:Cuantitativo:
et-EE	Estonian (Estonia)	Guanidinoatsetaat:SCnc:Pt:AmnF:Qn: Synonyms: Aine kontsentratsioon Amnionivedelik Juhuslik Kvantitatiivne
fr-CA	French (Canada)	Guanidinoacétate:Concentration de substance:Temps ponctuel:Liquide amniotique:Quantitatif:
fr-FR	French (France)	Guanidinoacétate:Moles/Volume:Ponctuel:Liquide amniotique:Numérique:
fr-BE	French (Belgium)	Guanidinoacétate:Concentration de substance:Temps ponctuel:Liquide amniotique:Quantitatif:
it-IT	Italian (Italy)	Guanidinoacetato:SCnc:Pt:Liquido amniotico:Qn: Synonyms: Chimica Concentrazione di Sostanza Liquido amniotico Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	guanidinoacetaat:mol/volume:moment:vruchtwater:kwantitatief:
pl-PL	Polish (Poland)	Guanidynooctan:stężenie molowe:punkt w czasie:płyn owodniowy:ilościowy:
pt-BR	Portuguese (Brazil)	Guanidinoacetato:#N/A:Pt:LiqAmni:Qn: Synonyms: glycocyamine; guanidoacetic acid; guanidinoacetic acid; GAA; Substance concentration; Level; Point in time; Random; Amn; Amniotic fluid; Amn fl; Amniotic flu; AF; Quantitative; QNT; Quant; Quan; Chemistry
ru-RU	Russian (Russian Federation)	Гуанидинацетат:МолКонц:ТчкВрм:Амниотич ждк:Колич: Synonyms: Амниотическая жидкость Количественный Молярность;Молярная объёмная концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Guanidinoasetat:SubKons:Zmlı:Amniyon sv:Kant: Synonyms: Amniyon mayii
zh-CN	Chinese (China)	胍基乙酸:物质的量浓度:时间点:羊水:定量型: Synonyms: GAA;胍乙酸;胍基醋酸克分子浓度;克分子浓度(单位体积);摩尔浓度;摩尔浓度(单位体积);物质的量浓度(单位体积) 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间羊膜水;胎水

Example Units

Unit	Source
umol/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.