5452-8
Deprecated CD23 in Blood
Deprecated
Status Information
- Status
- DEPRECATED
- Reason
- Duplicate
| Map-To | Long Common Name | Mapping Guidance |
|---|---|---|
| 14018-6 | CD23 cells/cells in Blood |
Part Descriptions
LP20016-9 CD23
Found on mature B-cells.
Associated with B-cell CLL and Nodal small lymphocytic lymphoma
Usually absent in mantle cell lymphoma
Source: Regenstrief Institute
LP20016-9 CD23
CD23, also known as Fc epsilon RII, or FcεRII, is the "low affinity" receptor for IgE, an antibody isotype involved in allergy and resistance to parasites and is important in regulation of IgE levels. Unlike many of the antibody receptors, CD23 is a C-type lectin. It is found on mature B cells, activated macrophages, eosinophils, follicular dendritic cells and platelets.
There are two forms of CD23: CD23a and CD23b. CD23a is unconditionally present on B cells, while CD23b requires IL-4 to be expressed on T-cells, monocytes, Langerhans cells, eosinophils and macrophages.
The allergen responsible in dust mite allergy, Der-p-1, is known to cleave CD23 from a cells surface. As CD23 is soluble it can move freely and interact with cells in plasma. Recent studies have shown that increased levels of soluble CD23 cause the recruitment of non-sensitised B-cells in the presentation of antigen peptides to allergen specific B-cells, therefore increasing the production of allergen specific IgE. IgE in turn is known to upregulate the cellular expression of CD23 and Fc epsilon RI (high affinity IgE receptor).
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Source: Wikipedia,
CD23
LOINC Names Get Info
- Fully-Specified Name
- CD23:
ACnc: Pt: WBC: Qn: - Long Common Name
- Deprecated CD23 in Blood
- Short Name
- Deprecated CD23 WBC-aCnc
- Display Name
- CD23 Qn (WBC)
- Consumer Name Alpha Get Info
- CD23, White blood cells
Part Model Get Info
Basic Attributes
- Class
- CELLMARK
- Type
- Laboratory
- First Released
- Version 1.0
- Last Updated
- Version 2.69 (MIN)
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | CD23: |
| el-GR | Greek (Greece) | CD23: Synonyms: ACnc CD23 CELLMARK Pt Qn Αριθμός λευκών αιμοσφαιρίων |
| es-AR | Spanish (Argentina) | CD23: |
| es-ES | Spanish (Spain) | CD23: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | CD23: |
| et-EE | Estonian (Estonia) | CD23: Synonyms: Juhuslik Kvantitatiivne Leukotsüüdid |
| fr-CA | French (Canada) | CD23: |
| fr-BE | French (Belgium) | CD23: |
| fr-FR | French (France) | CD23: |
| it-IT | Italian (Italy) | CD23: Synonyms: Concentrazione Arbitraria Globuli bianchi Modelli di superficie cellulare Punto nel tempo (episodio) |
| nl-NL | Dutch (Netherlands) | CD23: Synonyms: witte bloedcellen |
| pl-PL | Polish (Poland) | CD23: Synonyms: CD23 |
| pt-BR | Portuguese (Brazil) | CD23: Synonyms: B-6; |
| ru-RU | Russian (Russian Federation) | CD23: Synonyms: Количественный Произвольная концентрация Точка во времени; |
| tr-TR | Turkish (Turkey) | CD23: Synonyms: WBC |
| zh-CN | Chinese (China) | CD23: Synonyms: B6; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://