Version 2.77

Part Descriptions

LP200104-0   Hepatitis C virus core Ag
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LP200105-7   Hepatitis C virus core
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

Fully-Specified Name

Component
Hepatitis C virus core Ag
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method
IA

Additional Names

Short Name
HCV core Ag Ser IA-aCnc
Display Name
HCV core Ag IA Qn (S)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) Core antigen, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.27
Last Updated
Version 2.69
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG32754-0 Hepatitis C virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Hepatitis-C-Virus Core Ag:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
es-ES Spanish (Spain) Core del virus hepatitis C Antígeno:Concentración arbitraria:Punto temporal:Suero:Qn:IA
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Ag del núcleo del virus de la hepatitis C:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA French (Canada) Hépatite C virus core , Ag:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR French (France) Hépatite C virus core Ag:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
it-IT Italian (Italy) Epatite C virus, core , Ag:ACnc:Pt:Siero:Qn:IA
Synonyms: Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio) Siero Virus dell''epatite C Virus dell''epatite C core
nl-NL Dutch (Netherlands) Hepatitis C-virus core Ag:eenheid/volume:moment:serum:kwantitatief:immunoassay
Synonyms: antigeen IA
pl-PL Polish (Poland) Rdzeń wirusa zapalenia wątroby typu C Ag:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna
Synonyms: Antygen rdzeniowy wirusa zapalenia wątroby typu C
pt-BR Portuguese (Brazil) Hepatite C vírus Ag:#N/A:Pt:Soro:Qn:Imunoensaio
Synonyms: ; HCV; Hep C; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antigen; Antigens; Hepatit; Hepatis; Microbiology
tr-TR Turkish (Turkey) Hepatitis C virüs core Ag:SçKons:Zmlı:Ser:Kant:İA
Synonyms: Antijen İmmünölçüm, immünoassay
zh-CN Chinese (China) 丙型肝炎病毒核心 抗原:任意型浓度:时间点:血清:定量型:免疫测定法
Synonyms: Ag C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）核心 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 肝

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=54914-7