54914-7

Hepatitis C virus core Ag [Units/volume] in Serum by Immunoassay

Active

Part Descriptions

LP200104-0 Hepatitis C virus core Ag
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LP200105-7 Hepatitis C virus core
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LOINC Names Get Info

Fully-Specified Name: Hepatitis C virus core Ag:ACnc:Pt:Ser:Qn:IA
Long Common Name: Hepatitis C virus core Ag [Units/volume] in Serum by Immunoassay
Short Name: HCV core Ag Ser IA-aCnc
Display Name: HCV core Ag IA Qn (S)
Consumer Name Alpha Get Info: Hepatitis C virus (HCV) Core antigen, Blood

Part Model Get Info

Component
Hepatitis C virus core Ag
LP200104-0
- Analyte
  Hepatitis C virus core Ag
  LP200104-0
  - Component Numerator
    Hepatitis C virus core Ag
    LP200104-0
    - Component Numerator Core
      Hepatitis C virus core
      LP200105-7
    - Component Numerator Core Suffix
      Ag
      LP20666-1
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 2.27
Last Updated: Version 2.69 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG32754-0	Hepatitis C virus

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Virus hepatitidy C core Ag:Arbitrární koncentrace:Časový bod:Sérum:Kvantitativní:Imunoanalýza
de-DE	German (Germany)	Hepatitis-C-Virus Core Ag:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:Immunoassay
el-GR	Greek (Greece)	Πυρήνας ιού ηπατίτιδας C Αντιγόνο:ACnc:Pt:Ορός:Qn:IA Synonyms: ACnc C IA MICRO Pt Qn Αντιγόνο Ιός Ιός ηπατίτιδας C Ορός Πυρήνας ιού ηπατίτιδας C
es-ES	Spanish (Spain)	Core del virus hepatitis C Antígeno:Concentración arbitraria:Punto temporal:Suero:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Ag del núcleo del virus de la hepatitis C:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:Inmunoensayo
fr-CA	French (Canada)	Hépatite C virus core, Ag:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:IA
fr-FR	French (France)	Hépatite C virus core Ag:Arbitraire/Volume:Ponctuel:Sérum:Numérique:Immunoanalyse
it-IT	Italian (Italy)	Epatite C virus, core, Ag:ACnc:Pt:Siero:Qn:IA Synonyms: Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio) Siero Virus dell''epatite C Virus dell''epatite C core
nl-NL	Dutch (Netherlands)	Hepatitis C-virus core Ag:eenheid/volume:moment:serum:kwantitatief:immunoassay Synonyms: antigeen IA
pl-PL	Polish (Poland)	Rdzeń wirusa zapalenia wątroby typu C Ag:stężenie w jednostkach umownych:punkt w czasie:surowica:ilościowy:metoda immunologiczna Synonyms: Antygen rdzeniowy wirusa zapalenia wątroby typu C
pt-BR	Portuguese (Brazil)	Hepatite C vírus Ag:#N/A:Pt:Soro:Qn:Imunoensaio Synonyms: ; HCV; Hep C; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Antigen; Antigens; Hepatit; Hepatis; Microbiology
tr-TR	Turkish (Turkey)	Hepatitis C virüs core Ag:SçKons:Zmlı:Ser:Kant:İA Synonyms: Antijen İmmünölçüm, immünoassay
zh-CN	Chinese (China)	丙型肝炎病毒核心抗原:任意型浓度:时间点:血清:定量型:免疫测定法 Synonyms: Ag C 型;丙;丙型 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型丙型肝炎病毒（C 型肝炎病毒、HCV、Hep C、丙肝病毒、肝炎病毒 C 型）核心任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度传染性肝炎传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间肝

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.