54929-5
Tissue transglutaminase Ab [Titer] in Serum by Immunofluorescence
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Part Descriptions
LP40012-4 Tissue transglutaminase Ab
Anti-transglutaminase antibodies (ATA) are antibodies found more frequently in certain autoimmune diseases. High levels (titers) of ATA are found in almost all instances of coeliac disease. Given the association of ATA with coeliac disease, and the prevalence of the latter it is estimated that ~1% of the population have potentially pathogenic levels of ATA.
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Source: Wikipedia,
Wikipedia
LP40012-4 Tissue transglutaminase Ab
Tissue transglutaminase (abbreviated as TG2 or tTG) is an enzyme (EC 2.3.2.13) of the transglutaminase family. Like other transglutaminases, it crosslinks proteins between an ε-amino group of a lysine residue and a γ-carboxamide group of glutamine residue, creating an inter- or intramolecular bond that is highly resistant to proteolysis (protein degradation). It is an autoantigen in celiac disease, and is also known to play a role in apoptosis, cellular differentiation and matrix stabilisation. Serology for anti-tTG antibodies has superseded older serological tests (anti-endomysium, anti-gliadin and anti-reticulin) and has a strong sensitivity (99%) and specificity (>90%) for identifying coeliac disease. Modern anti-tTG assays rely on a human recombinant protein as an antigen.
Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details.
Source: Wikipedia,
Wikipedia
LOINC Names Get Info
- Fully-Specified Name
- Tissue transglutaminase Ab:
Titr: Pt: Ser: SemiQn: IF - Long Common Name
- Tissue transglutaminase Ab [Titer] in Serum by Immunofluorescence
- Short Name
- tTG Ab Titr Ser IF
- Display Name
- tTG Ab IF (S) [Titer]
- Consumer Name Alpha Get Info
- tTG antibody, Blood
Part Model Get Info
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.27
- Last Updated
- Version 2.75 (MAJ)
- Order vs. Observation
- Both
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Tkáňová transglutamináza Ab: |
| el-GR | Greek (Greece) | Ιστική τρανσγλουταμινάση Αντίσωμα: Synonyms: Pt SERO Titr Ανοσοφθορισμός Αντίσωμα Ημιποσοτική Ιστική τρανσγλουταμινάση Ορός |
| es-ES | Spanish (Spain) | Transglutaminasa tisular Anticuerpos: Synonyms: Semicuantitativo |
| es-MX | Spanish (Mexico) | Transglutaminasa tisular Ab: |
| fr-CA | French (Canada) | Transglutaminase de tissu, Ac: |
| fr-FR | French (France) | Transglutaminase tissulaire Ac: |
| it-IT | Italian (Italy) | Transglutaminasi tissutale Ab: Synonyms: anticorpo Immunofluorescenza (IF) Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant Titolo |
| nl-NL | Dutch (Netherlands) | tissue transglutaminase As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Transglutaminaza tkankowa Ab: |
| pt-BR | Portuguese (Brazil) | Transglutaminase tecidual Ac: Synonyms: ; |
| zh-CN | Chinese (China) | 组织谷氨酰胺转移酶 抗体: Synonyms: Ab; |
Example Units
| Unit | Source |
|---|---|
| {titer} | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://