55347-9
Ecarin clotting time (ECT) in Blood by Coagulation assay
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Part Description
LP94560-7 Coagulation ecarin induced
Ecarin clotting time (ECT) is a laboratory test used to monitor anticoagulation during treatment with hirudin, an anticoagulant medication which was originally isolated from leech saliva. Ecarin, the primary reagent in this assay, is derived from the venom of the saw-scaled viper, Echis carinatus.
In the clinical assay, a known quantity of ecarin is added to the plasma of a patient treated with hirudin. Ecarin activates prothrombin through a specific proteolytic cleavage, which produces meizothrombin, a prothrombin-thrombin intermediate which retains the full molecular weight of prothrombin, but possesses a low level of procoagulant enzymatic activity. Crucially, this activity is inhibited by hirudin and other direct thrombin inhibitors, but not by heparin. The ECT is also unaffected by prior treatment with coumadin or the presence of phospholipid-dependent anticoagulants, such as lupus anticoagulant. Thus, the ECT is prolonged in a specific and linear fashion with increasing concentrations of hirudin.
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Source: Wikipedia
, Ecarin clotting time
Fully-Specified Name
- Component
- Coagulation ecarin induced
- Property
- Time
- Time
- Pt
- System
- Bld
- Scale
- Qn
- Method
- Coag
Additional Names
- Long Common Name
- Ecarin clotting time (ECT) in Blood by Coagulation assay
- Short Name
- ECT Bld
- Display Name
- ECT Coag (Bld) [Time]
- Consumer Name Alpha Get Info
- ECT, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 2.27
- Last Updated
- Version 2.66 (MIN)
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Πήξη επαγόμενη από εκαρίνη: Synonyms: Time Πήξη Πήξη επαγόμενη από εκαρίνη |
es-ES | Spanish (Spain) | Retracción del coágulo inducida: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Coagulación inducida por ecarina: |
fr-CA | French (Canada) | Temps de céphaline induite par écarine: |
fr-FR | French (France) | Temps d'écarine: |
fr-BE | French (Belgium) | Temps de céphaline induite par écarine: Synonyms: Test d''Hémostase |
it-IT | Italian (Italy) | Coagulazione ecarin indotta: Synonyms: Punto nel tempo (episodio) Sangue Studio di coagulazione Tempo (e.g. secondi) Test di coagulazione |
nl-NL | Dutch (Netherlands) | stolling ecarinegeïnduceerd: Synonyms: coagulatiemethode stolling ecarine geinduceerd |
pl-PL | Polish (Poland) | ECT: |
pt-BR | Portuguese (Brazil) | Ecarin coagulação induzida: Synonyms: ; |
ru-RU | Russian (Russian Federation) | Коагуляция экарин индуцированная: Synonyms: Анализ факторов свертывания крови; |
tr-TR | Turkish (Turkey) | Koagülasyon ekarin uyarılmış: |
zh-CN | Chinese (China) | 锯鳞蝰蛇毒诱导型凝血过程: Synonyms: ecarin 倾斜试管; |
Example Units
Unit | Source |
---|---|
s | Example UCUM Units |
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