5573-1

Aluminum [Mass/mass] in Hair

Active

Part Description

LP16800-2 Aluminum
Aluminium (Al) is a metal which is distributed throughout our environment. It has been used since approximately 1887. Al is widely used in multiple industries and consumer products. It has no known function in biology. Al usually enters the human body via cooking utensils or pharmicological agents such as antacids (Al (OH)3 )and antiperspirants. Aluminum salts are remarkably nontoxic, aluminum sulfate having an LD50 of 6207 mg/kg (oral, mouse), which corresponds to 500 grams for an 80 kg (180 lb) person. Aluminum is excreted by filtration by the glomeruli of the kidney. Patients in renal failure lose the ability to clear aluminum, and aluminum toxicity may be a concern. Aluminum accumulates in the blood and binds to proteins such as albumin, and then distributed throughout the body.Because aluminum competes with calcium for absorption, increased amounts of dietary aluminum may contribute to the reduced skeletal mineralization (osteopenia) observed in preterm infants and infants with growth retardation. In very high doses, aluminum is associated with altered function of the blood-brain barrier. A small percentage of people are allergic to aluminum and experience contact dermatitis, digestive disorders, vomiting or other symptoms upon contact or ingestion of products containing aluminum. In those without allergies, aluminum is not as toxic as heavy metals, but there is evidence of some toxicity if consumed in amounts greater than 40 mg/day per kg of body mass. Aluminum is classified as a non-carcinogen by the US Department of Health and Human Services. In case of suspected sudden intake of a large amount of aluminum, deferoxamine mesylate may be given to help eliminate it from the body by chelation. (Tietz: Clinical Guide to Laboratory Tests, Fourth Edition)
The mechanism of how the neurotoxicity of AI occurs is still unclear. Evidence suggests that oxidative stress and inflammatory processes lead to cell death. As a neurotoxin, Al is considered has been linked to the development of neurodegenerative diseases, including Alzheimer's disease (AD), dementia, Amyotrophic Lateral Sclerosis (ALS) Parkinsonism and even Gulf war syndrome. PMID: 27479193 (for human medicine)

Veterinary Medicine:
In veterinary medicine, the impact of aluminum toxicity is similar. An animal proven to have aluminum toxicity from an ingested foreign body had symptoms of muscle twitching and convulsions during exercise, which worsened to weakened limbs and coma until the source of the toxicity was removed. PMID: 23609067 Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Aluminum:MCnt:Pt:Hair:Qn:
Long Common Name: Aluminum [Mass/mass] in Hair
Short Name: Aluminum Hair-mCnt
Display Name: Aluminum (Hair) [Mass/Mass]
Consumer Name Alpha Get Info: Aluminum, Hair

Part Model Get Info

Component
Aluminum
LP16800-2
- Analyte
  Aluminum
  LP16800-2
  - Component Numerator
    Aluminum
    LP16800-2
    - Component Numerator Core
      Aluminum
      LP16800-2
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MCnt
LP6828-0
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Hair
LP7280-3
- System Core
  Hair
  LP7280-3
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 1.0
Last Updated: Version 2.19 (MIN)
Order vs. Observation: Both

Member of these Panels

LOINC	Long Common Name
76770-7	Trace elements panel - Hair

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Hliník:Hmotnostní obsah:Časový bod:Vlas:Kvantitativní:
de-DE	German (Germany)	Aluminium:Massengehalt:Zeitpunkt:Haar(e):Quantitativ:
el-GR	Greek (Greece)	Αλουμίνιο:MCnt:Pt:Μαλλιά:Qn: Synonyms: DRUG/TOX MCnt Pt Qn Αλουμίνιο Μαλλιά
es-AR	Spanish (Argentina)	aluminio:contenido másico:punto en el tiempo:pelo:cuantitativo:
es-MX	Spanish (Mexico)	Aluminio:Contenido masivo:Punto temporal:Cabello:Cuantitativo:
es-ES	Spanish (Spain)	Aluminio:Contenido de masa:Punto temporal:Pelo:Qn: Synonyms: Cuantitativo
et-EE	Estonian (Estonia)	Alumiinium:MCnt:Pt:Hair:Qn: Synonyms: Juhuslik Juuksed Kvantitatiivne
fr-CA	French (Canada)	Aluminium:Contenu de masse:Temps ponctuel:Cheveu:Quantitatif:
fr-FR	French (France)	Aluminium:Masse/Masse:Ponctuel:Cheveux:Numérique:
fr-BE	French (Belgium)	Aluminium:Contenu de masse:Temps ponctuel:Cheveu:Quantitatif: Synonyms: Al
it-IT	Italian (Italy)	Alluminio:MCnt:Pt:Pelo:Qn: Synonyms: Contenuto di Massa Livelli farmacologici e tossicologia Punto nel tempo (episodio)
ko-KR	Korean (Korea, Republic Of)	알루미늄:질량구성:검사시점:모발:정량:
nl-NL	Dutch (Netherlands)	aluminium:massa/massa:moment:haar:kwantitatief:
pt-BR	Portuguese (Brazil)	Alumínio:MCnt:Pt:Cabelo:Qn: Synonyms: AL; Aluminium; Mass content; Point in time; Random; Har; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY
ru-RU	Russian (Russian Federation)	Алюминий:МассСод:ТчкВрм:Волосы:Колич: Synonyms: Количественный Масса содержание Точка во времени;Момент
tr-TR	Turkish (Turkey)	Aluminyum:Kütlİçrk:Zmlı:Saç:Kant:
zh-CN	Chinese (China)	铝:质量含量:时间点:毛发:定量型: Synonyms: AL 单位质量的质量数;质量含量(单位质量) 发;头发;毛可用数量表示的;定量性;数值型;数量型;连续数值型标尺时刻;随机;随意;瞬间毒品毒品类药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ug/g	Example UCUM Units
ug/g	eCHN

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=5573-1

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.