Version 2.76

Part Descriptions

LP29082-2   Immunoglobulin light chains.lambda.free
Healthy patients have the majority of light chains in serum bound to heavy chains. Low levels of free light chains (unbound) are normal due to the over-production and secretion of free light chains by plasma cells. In the kidneys, the free light chains are selectively reabsorbed by the tubular cells, so their presence in urine is likely due to secretion into the urinary tract. Elevation of monoclonal free light chains in serum or urine signal malignant plasma cell proliferation (multiple myeloma), primary amyloidosis, or light chain deposition disease. Elevation of polyclonal free light chains suggests autoimmune diseases such as systemic lupus erythematosus. (Information from Freelite Beckman Coulter IMMAGE II package insert, Version 23, Feb 2009) Source: Regenstrief Institute

LP6336-4   Immunofixation
Plasma or concentrated urine is deposited on a gel. With an electrical current the proteins are sorted in function of their size, after which antigens for each targeted type of immunoglobulin are deposited on the gel. Thus more or less narrow bands appear on the gel, marking the location of the various immunoglobulines.
Immunofixation tends to replace protein electrophoresis because:

• it is faster (results within three hours);
• it is somewhat more sensitive. Immunofixation may reveal an immunoglobulin missed out by protein electrophoresis, especially at low concentrations (less than 1 gram/litre);
• it can be partially automated and can be used in more laboratories;
• it is more easily read and interpreted.

Immunofixation is however only sensitive to immunoglobulins and is more expensive than protein electrophoresis. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Immunofixation

Fully-Specified Name

Component
Immunoglobulin light chains.lambda.free
Property
PrThr
Time
Pt
System
Urine
Scale
Ord
Method
Immunofixation

Additional Names

Short Name
Lambda LC Free Ur Ql IFE
Display Name
Immunoglobulin light chains.lambda.free Immunofixation Ql (U)
Consumer Name Alpha Get Info
Free lambda light chains, Urine

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.63
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016. The LCN was changed from 'Immunoglobulin light chains lambda.free' to 'Lambda light chains.free' for better readability.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG16700-3 Immunoglobulin light chains.lambda.free|PrThr|Pt|ANYUrine
LG36223-2 Immunoglobulin light chains.lambda.free|PrThr|Urine

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Immunglobulin-Leichtketten.lambda.frei:Nachweis oder Schwellenwert:Zeitpunkt:Urin:Ordinal:Immunfixation
es-ES Spanish (Spain) Cadenas ligeras lambda libres:PrThr:Punto temporal:Orina:Ord:Inmunofijación
es-MX Spanish (Mexico) Cadenas ligeras de inmunoglobulina lambda.libre:Presencia o umbral:Punto temporal:Orina:Ordinal:Inmunofijación
et-EE Estonian (Estonia) Immuunglobuliinide kerged lambdaahelad:PrThr:Pt:U:Ord:Immuunfiksatsioon
Synonyms: Immuunglobuliinide kerged lambdaahelad Järgarvuline Juhuslik Uriin
fr-CA French (Canada) Chaînes légères des immunoglobulines.lambda.libre:Présence-Seuil:Temps ponctuel:Urine:Ordinal:Immunofixation
fr-FR French (France) Immunoglobuline chaines légères libres lambda:Présence/Seuil:Ponctuel:Urine:Qualitatif:Immunofixation
fr-BE French (Belgium) Chaînes légères des immunoglobulines.lambda.libre:PrThr:Temps ponctuel:Urine:Ordinal:Immunofixation
Synonyms: FLC.lambda.libre, FLC.lambda LC LC. Lambda
it-IT Italian (Italy) Immunoglobuline, catene leggere.lambda.libere:PrThr:Pt:Urine:Ord:Immunofissazione
Synonyms: Catene leggere delle immunoglobuline Catene leggere lambda delle immunoglobuline Catene leggere lambda libere delle immunoglobuline Chimica Presenza o Soglia Punto nel tempo (episodio)
nl-NL Dutch (Netherlands) immunoglobuline lichte ketens.lambda.vrij:aanwezigheid:moment:urine:ordinaal:immunofixatie
pl-PL Polish (Poland) Łańcuchy lekkie immunoglobulin.lambda.wolne:granica wykrywalności:punkt w czasie:mocz:półilościowy:immunofiksacja
Synonyms: Łańcuchy lekkie immunoglobulin Łańcuchy lekkie lambda immunoglobuliny Łańcuchy lekkie wolne lambda
pt-BR Portuguese (Brazil) Imunoglobulinas cadeias leves.lambda.livre:#N/A:Pt:Urina:Ord:Imunofixação
Synonyms: ; Lambda LC Free; BJ Protein; BJP; Bence Jones protein; Arbitrary concentration; Point in time; Random; Ur; UR; Urn; UA; Ql; Ordinal; QL; Qualitative; Qual; Screen; IFE; Ifix; Immunofixation electrophoresis; Immune globulin; Imunoglbon; Immuno; Imunoglobn; Immunoglobin; Immunoglob; FR; Non-protein bound; Chain; Chemistry
ru-RU Russian (Russian Federation) Иммуноглобулин легкие цепи.лямбда.свободная:PrThr:ТчкВрм:Моча:Пор:Иммунофиксация
Synonyms: Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) İmmünglobulin hafif zincirler.lambda.serb:MevcEşik:Zmlı:İdrar:Srl:İmmünfiksasyon
Synonyms: Mevcut
zh-CN Chinese (China) 免疫球蛋白轻链.Lambda 型.游离型:存在情况或阈值:时间点:尿液:序数型:免疫固定电泳分析法
Synonyms: Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白(Bence Jones protein,BJ Protein,BJP);本周蛋白;本-周蛋白 IFE;Ifix;免疫固定法;免疫固定电泳(Immunofixation electrophoresis,IFE);免疫固定电泳法 Ig Lambda LC;Lambda 型免疫球蛋白轻链;Lambda 型轻链;Lambda 轻链;λ型免疫球蛋白轻链;λ型轻链;λ轻链;免疫球蛋白轻链.Lambda;免疫球蛋白轻链.λ型;轻链.Lambda;轻链.Lambda 型;轻链.λ;轻链.λ型 丙种球蛋白 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫球蛋白(Immunoglobulin,Ig) 免疫球蛋白类 免疫球蛋白轻链.Lambda 型.游离;免疫球蛋白轻链.Lambda.游离;免疫球蛋白轻链.Lambda.游离型;免疫球蛋白轻链.λ型.游离;免疫球蛋白轻链.λ型.游离型;游离 Lambda LC;游离 Lambda 型免疫球蛋白轻链;游离 Lambda 型轻链;游离 Lambda 轻链;游离λ型免疫球蛋白轻链;游离λ型轻链;游离λ轻链;游离型 Lambda LC;游离型 Lambda 免疫球蛋白轻链;游离型 Lambda 型免疫球蛋白轻链;游离型 Lambda 型轻链;游离型 Lambda 轻链;游离型 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 尿;小便;下泉 时刻;随机;随意;瞬间 游离 链 非蛋白结合型 非蛋白质结合型

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=56481-5