Version 2.76

Part Description

LP30804-6   PL-7
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes. Source: Regenstrief LOINC, PMID: 23573256

Fully-Specified Name

Component
Pl-7 Ab
Property
PrThr
Time
Pt
System
Ser
Scale
Ord
Method
IB

Additional Names

Short Name
PL7 Ab Ser Ql IB
Display Name
PL-7 Ab IB Ql (S)
Consumer Name Alpha Get Info
PL-7 antibody, Blood

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
13526

Member of these Groups Get Info

LOINC Group Group Name
LG13328-6 Pl-7 Ab|PrThr|Pt|ANYBldSerPl

Language Variants Get Info

Tag Language Translation
de-AT German (Austria) Synonyms: PL-7-AK ql. IB
es-ES Spanish (Spain) Pl-7 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
es-MX Spanish (Mexico) PL-7 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
et-EE Estonian (Estonia) PL-7 antikehad:PrThr:Pt:S:Ord:IB
Synonyms: Järgarvuline Juhuslik Seerum
fr-CA French (Canada) Pl-7 , Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FR French (France) PL-7 anticorps:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
fr-BE French (Belgium) Pl-7 Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
Synonyms: Anticorps
it-IT Italian (Italy) PL-7 Ab:PrThr:Pt:Siero:Ord:IB
Synonyms: anticorpo Immunoblot (IB) Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) PL-7 As:aanwezigheid:moment:serum:ordinaal:immunoblotting
Synonyms: antistof; antilichaam IB
pt-BR Portuguese (Brazil) Pl-7 Ac:#N/A:Pt:Soro:Ord:Imunoblot
Synonyms: ; PL7; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Western blot; WB; Immune blot; Immunobl; Blt; WBLOT; West blt; West blot; RIBA; Immunoblot; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Serology
ru-RU Russian (Russian Federation) PL-7 Ат:PrThr:ТчкВрм:Сыв:Пор:ИБ
Synonyms: Антитело Иммуноблот (ИБ) Порядковый Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) PL-7 Ab:MevcEşik:Zmlı:Ser:Srl:IB
Synonyms: Ak Mevcut
zh-CN Chinese (China) Pl-7 抗体:存在情况或阈值:时间点:血清:序数型:免疫印迹法
Synonyms: Ab;自身抗体 Pl-7 Ab 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 先天性炎性肌病 先天性炎症性肌病 免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 时刻;随机;随意;瞬间 特发性炎性肌病 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=56744-6