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Part Description

LP96779-1   Hepatitis C virus NS4
Hepatitis C virus (HCV) is a small (50 nm in size), enveloped, single-stranded, positive sense RNA virus in the genus hepacivirus, which is in the Flaviviridae family. More than 170 million people worldwide are affected by hepatitis C, and the majority of patients with acute hepatitis C develop chronic HCV infection, which can result in liver cirrhosis, hepatic failure or hepatocellular carcinoma. The HCV core protein is a highly basic, RNA-binding protein that forms the viral capsid. The E1 and E2 envelope glycoproteins are necessary for viral entry and fusion. Non-structural proteins include NS2, NS3, NS4A and 4B, and NS5A and 5B. The NS2-NS3 complex functions as a protease, and NS3 also has a helicase/NTPase domain. NS4A is a cofactor of NS3 protease activity. NS3-NS4A protease is one target of anti-HCV drugs. NS4B is a membrane anchor for the replication complex, and NS5A plays a role in regulating viral replication. NS5B is an RNA-dependent RNA polymerase. [NCBI Books: NBK1630] Source: Regenstrief LOINC, NCBI Books: NBK1630

LOINC Names Get Info

Fully-Specified Name
Hepatitis C virus NS4 Ab:PrThr:Pt:Ser:Ord:IB
Long Common Name
Hepatitis C virus NS4 Ab [Presence] in Serum by Immunoblot
Short Name
HCV NS4 Ab Ser Ql IB
Display Name
HCV NS4 Ab IB Ql (S)
Consumer Name Alpha Get Info
Hepatitis C virus (HCV) NS4 antibody, Blood

Part Model Get Info

  • Component
    Hepatitis C virus NS4 Ab
    LP96490-5
    • Analyte
      Hepatitis C virus NS4 Ab
      LP96490-5
      • Component Numerator
        Hepatitis C virus NS4 Ab
        LP96490-5
        • Component Numerator Core
          Hepatitis C virus NS4
          LP96779-1
        • Component Numerator Core Suffix
          Ab
          LP20667-9
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    PrThr
    LP217195-9
  • Time
    Pt
    LP6960-1
  • System
    Ser
    LP7567-3
    • System Core
      Ser
      LP7567-3
    • Super System
      NULL
       
  • Scale
    Ord
    LP7751-3
  • Method
    IB
    LP6320-8

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.58 (MIN)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Panels

LOINCLong Common Name
75887-0HCV antibody RIBA tests - Meaningful Use set by Immunoblot

Member of these Groups Get Info

LOINC GroupGroup Name
LG32754-0Hepatitis C virus

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Virus hepatitidy C NS4 Ab:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Imunoblot
de-DEGerman (Germany)Hepatitis-C-Virus NS4 Ak:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunoblot
el-GRGreek (Greece)Ιός ηπατίτιδας C NS4 Αντίσωμα:PrThr:Pt:Ορός:Ord:IB
Synonyms: C IB MICRO Ord PrThr Pt Αντίσωμα Ιός Ιός ηπατίτιδας C Ιός ηπατίτιδας C NS4 Ορός
es-ESSpanish (Spain)Hepatitis C virus NS4 Anticuerpos:PrThr:Punto temporal:Suero:Ord:Inmunoblot (IB)
es-MXSpanish (Mexico)Virus de la hepatitis C NS4 Ab:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunotransferencia
et-EEEstonian (Estonia)C-hepatiidi viirus NS4 antikehad:PrThr:Pt:S:Ord:IB
Synonyms: Järgarvuline Juhuslik Seerum
fr-CAFrench (Canada)Virus de l'hépatite C NS4, Ac:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:Immunoblot
fr-FRFrench (France)Hépatite C virus NS4 Ac:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoblot
fr-BEFrench (Belgium)Virus de l'hépatite C NS4 Ac:PrThr:Temps ponctuel:Sérum:Ordinal:Immunoblot
Synonyms: Anticorps HCV HCV. NS4
it-ITItalian (Italy)Epatite C virus, NS4 Ab:PrThr:Pt:Siero:Ord:IB
Synonyms: anticorpo Immunoblot (IB) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Siero Virus dell''epatite C Virus dell''epatite C NS4
nl-NLDutch (Netherlands)Hepatitis C-virus NS4 As:aanwezigheid:moment:serum:ordinaal:immunoblotting
Synonyms: antistof; antilichaam IB
pl-PLPolish (Poland)Wirus zapalenia wątroby typu C NS4 Ab:granica wykrywalności:punkt w czasie:surowica:uporządkowany:immunoblotting
pt-BRPortuguese (Brazil)Hepatitis C vírus NS4 Ac:#N/A:Pt:Soro:Ord:Imunoblot
Synonyms: ; HCV NS4; Hep C; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Western blot; WB; Immune blot; Immunobl; Blt; WBLOT; West blt; West blot; RIBA; Immunoblot; Antibodies; Autoantibody; Antibody; Autoantibodies; Antby; Acy; Anti; Hepatit; Hepatis; Microbiology
ru-RURussian (Russian Federation)Гепатит C вирус NS4 Ат:PrThr:ТчкВрм:Сыв:Пор:ИБ
Synonyms: Антитело Иммуноблот (ИБ) Порядковый Сыворотка Точка во времени;Момент
tr-TRTurkish (Turkey)Hepatit C virüsü NS4 Ab:MevcEşik:Zmlı:Ser:Srl:IB
Synonyms: Ak Mevcut
zh-CNChinese (China)丙型肝炎病毒 NS4 抗体:存在情况或阈值:时间点:血清:序数型:免疫印迹法
Synonyms: Ab;自身抗体 C 型;丙;丙型 HCV NS4;HCVNS4;Hep C NS4;丙肝病毒 NS4;肝炎病毒 C 型 NS4 HCV;Hep C;丙型肝炎;丙肝;丙肝病毒;肝炎病毒 C 型 传染性肝炎 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫印迹;西部印迹法;Immunoblot;immunoblotting;IB 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 肝

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=56930-1