Version 2.77

Part Descriptions

LP14377-3   Aldosterone
Aldosterone is a steroid hormone produced by the outer-section (zona glomerulosa) of the adrenal cortex in the adrenal gland to regulate sodium and potassium balance in the blood. It is synthesized from cholesterol by aldosterone synthase, which is absent in other sections of the adrenal gland. It is the sole endogenous member of the class of mineralocorticoids. Acting on mineralocorticoid receptors (MR) on principal cells in the collecting ducts of the kidneys, it increases the permeability of their apical (luminal) membrane to potassium and sodium and activates their basolateral Na+K+ pumps, stimulating ATP hydrolysis, reabsorbing sodium (Na+) ions and water into the blood, and excreting potassium (K+) ions into the urine. Aldosterone also stimulates H+ secretion by intercalated cells in the collecting duct, regulating plasma bicarbonate (HCO3-) levels and its acidbase balance. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Aldosterone (Wikipedia)

LP14377-3   Aldosterone
Used to detect hyper and hypo aldosteronisnm. Hypoaldosteronism can occur in any condition that causes destruction or dysfunction of the adrenal gland.1,2,4 Hypoaldosterism can be due to primary adrenal insufficiency , congenital adrenal hypoplasia, acquired secondary aldosterone deficiency (hyporeninemic hypoaldosteronism), and acquired Hyporeninemic hypoaldosteronism is the most common form of isolated hypoaldosteronism and is results from impaired renin release from the kidney. Congenital hypoaldosteronism caused by inherited enzymatic defects in aldosterone biosynthesis are rare. Corticosterone methyloxidase I (CMO I) deficiency is associated with elevated serum levels of corticosterone and low levels of 18-hydroxy-corticosterone and aldosterone. Corticosterone methyloxidase II (CMO II) deficiency produces high levels of 18-hydroxy-corticosterone, the immediate precursor of aldosterone.
Acquired primary hypoaldosteronism can be caused by the administration of heparin. Also, persistently hypotensive, critically ill patients with sepsis, pneumonia, peritonitis, cholangitis, and liver failure can have inappropriately low plasma aldosterone concentrations in relation to elevated plasma renin activity. Primary hyperaldosteronism, also referred to as Conn syndrome, is due to overproduction of aldosterone by one or both of the adrenal glands. Some recent studies suggest that 10% to 15% of Hyper thyroidism cases are due to (or associated with ) primary hyperaldosteronism. Secondary hyperaldosteronism is relatively common and can occur as the result of any condition that decreases blood flow to the kidneys (ie, renal artery stenosis), decreases blood pressure, or lowers plasma sodium levels. Secondary hyperaldosteronism may also be seen with cirrhosis, congestive heart failure. and toxemia of pregnancy. Several studies have suggested that high-normal aldosterone levels predict development of high blood pressure in normotensive subjects and that increased aldosterone action contributes to hypertension, cardiovascular fibrosis, and cardiac hypertrophy. Source: Regenstrief Institute

Fully-Specified Name

Component
Aldosterone^pre 250 ug corticotropin IM
Property
MCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Short Name
Aldost pre 250 ug ACTH IM SerPl-mCnc
Display Name
Aldosterone pre 250 ug corticotropin IM [Mass/Vol]
Consumer Name Alpha Get Info
Aldosterone before 250 ug Corticotropin intramuscular, Blood

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.70
Order vs. Observation
Observation

Member of these Groups Get Info

LOINC Group Group Name
LG50721-6 Aldosterone^pre 250 ug corticotropin IM|Pt|Ser/Plas

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Aldosterona^antes de 250 ug de corticotropina IM:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Aldosterona ^antes de 250 ug de corticotropina IM:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CA French (Canada) Aldostérone^pré 250 ug hormone adrénocorticotrope IM:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FR French (France) Aldostérone avant synacthène (250µg,IM):Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BE French (Belgium) Aldostérone^Pré 250 ug hormone adrénocorticotrope IM:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: ACTH avant ACTH IM 250µg Stimulation ACTH 250µg. Avant injection
it-IT Italian (Italy) Aldosterone^pre 250 ug corticotropina IM:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Concentrazione di Massa Plasma prima di 250 ug di corticotropina prima di 250 ug di corticotropina IM Punto nel tempo (episodio) Siero Siero o Plasma Test di provocazione
nl-NL Dutch (Netherlands) aldosteron^voor 250 ug ACTH IM:massa/volume:moment:serum of plasma:kwantitatief:
Synonyms: adrenocorticotroop hormoon; adrenocorticotrofine; corticotrofine
pt-BR Portuguese (Brazil) Aldosterona^pré 250 ug corticotrofina IM:#N/A:Pt:Sor/Plas:Qn:
Synonyms: Before; ACTH; Rc206; c74; Cortrosyn; c206; Adrenocorticotropin; Adrenocorticotrophic hormone; Aldost; pre 250 ug ACTH IM; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; mcg; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RU Russian (Russian Federation) Альдостерон^до 250 мкг кортикотропина внутримышечно:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация Плазма Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Aldosteron^önc 250 ug IM kortikotropin:KütlKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 醛固酮^在肌肉注射250 ug促肾上腺皮质激素之前:质量浓度:时间点:血清/血浆:定量型:
Synonyms: ACTH ACTH;亲皮质素;促皮质素 ug XXX刺激 - 在...之前 μg 之前于250 ug 促肾上腺皮质激素 IM;之前于肌肉注射250 ug促肾上腺皮质激素;之前于肌肉注射250微克促肾上腺皮质激素;在250 ug 促肾上腺皮质激素 IM之前;在肌肉注射250微克促肾上腺皮质激素之前 之前于给予250 ug促肾上腺皮质激素;之前于给予250微克促肾上腺皮质激素;在给予250微克促肾上腺皮质激素之前 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 水平;浓度;质量浓度(单位体积) 血清或血浆 醛基甾酮;醛甾酮;醛皮质酮;醛类脂醇

Example Units

Unit Source
pg/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=57596-9