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Part Description

LP97520-8   5-Alpha tetrahydrocortisol
5 alpha-Tetrahydrocortisol is a normal human metabolite. However its increased ratio (5alpha-Tetrahydrocortisol + Tetrahydrocortisol) over Tetrahydrocortisone in urine is the biochemical marker for the syndrome of apparent mineralocorticoid excess (AME). AME is a heritable form of hypertension due to an inborn error of cortisol metabolism and is characterized by hypokalemia and low renin levels despite subnormal or normal levels of aldosterone and other known mineralocorticoids. The syndrome is attributable to congenital deficiency of the enzyme 11 beta-hydroxydehydrogenase (11 beta-HSD), which converts cortisol to biologically inactive cortisone. This results in a prolonged half-life of Cortisol, which acts at the kidney level as a potent mineralocorticoid. PMID: 8732999 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, 5-Alpha tetrahydrocortisol

LOINC Names Get Info

Fully-Specified Name
5-Alpha tetrahydrocortisol^pre dose dexamethasone:MRat:24H:Urine:Qn:
Long Common Name
5-Alpha tetrahydrocortisol [Mass/time] in 24 hour Urine --pre dose dexamethasone
Short Name
5-A THF Pre Dex 24h Ur-mRate
Display Name
5-Alpha tetrahydrocortisol pre dose dexamethasone (24H U) [Mass/Time]
Consumer Name Alpha Get Info
5-Alpha tetrahydrocortisol before dose dexamethasone, Urine

Part Model Get Info

  • Component
    5-Alpha tetrahydrocortisol^pre dose dexamethasone
    LP304796-8
    • Analyte
      5-Alpha tetrahydrocortisol
      LP97520-8
      • Component Numerator
        5-Alpha tetrahydrocortisol
        LP97520-8
        • Component Numerator Core
          5-Alpha tetrahydrocortisol
          LP97520-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      pre dose dexamethasone
      LP35651-6
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MRat
    LP6833-0
  • Time
    24H
    LP6924-7
  • System
    Urine
    LP7681-2
    • System Core
      Urine
      LP7681-2
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHAL
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Observation

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)5-alfa-tetrahydrokortizol^Před dávkou dexamethasonu:Hmotnostní tok:24 hodin:Moč:Kvantitativní:
el-GRGreek (Greece)5-α-τετραϋδροκορτιζόλη^προ δόσης δεξαμεθαζόνης:MRat:24H:Ούρα:Qn:
Synonyms: 24H 5-α-τετραϋδροκορτιζόλη CHAL MRat Qn Δεξαμεθαζόνη Ούρα προ δόσης προ δόσης δεξαμεθαζόνης Τετραϋδροκορτιζόλη
es-ESSpanish (Spain)5-Alfa tetrahidrocortisol^Pre dosis dexametasona:Indice de masa:24 horas:Orina:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)5-alfa tetrahidrocortisol^ predosis dexametasona:Tasa de masa:24H:Orina:Cuantitativo:
fr-CAFrench (Canada)5-alpha tétrahydrocortisol^pré dose dexaméthasone:Débit de masse:24 h:Urine:Quantitatif:
fr-FRFrench (France)5-alpha tétrahydrocortisol^avant dexaméthasone:Masse/Temps:24H:Urine:Numérique:
fr-BEFrench (Belgium)5-Alpha tétrahydrocortisol^Pré dose dexaméthasone:Débit de masse:24 h:Urine:Quantitatif:
Synonyms: Avant dose
it-ITItalian (Italy)5-Alfa tetraidrocortisolo^pre dose desametasone:MRat:24h:Urine:Qn:
Synonyms: 24 Ore Indice di Massa prima di dose prima di dose di desametasone Test di provocazione
nl-NLDutch (Netherlands)5-alfa-tetrahydrocortisol^voor dosis dexamethason:massa/tijd:24 uur:urine:kwantitatief:
Synonyms: 24U
pl-PLPolish (Poland)5-Alfa tetrahydrokortyzol^przed dawką deksametazonu:wskaźnik masowy w jednostce czasu:24h:mocz:ilościowy:
Synonyms: 24 godziny przed podaniem dawki przed podaniem dawki deksametazonu
pt-BRPortuguese (Brazil)5-Alfa tetrahidrocortisol^pré dose de dexametasona:#N/A:24H:Urina:Qn:
Synonyms: ; THF; THC; Before; Decadron; Dexameth; Dexone; Hexadrol; 5-A THF; 5A-tetrahydrocortisol; Pre Dex; mRate; Mass rate; 1 day; 24 hours; 24HR; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Alfa; CHEMISTRY.CHALLENGE TESTING; CHEMISTRY.CHALLENGE TESTING
ru-RURussian (Russian Federation)5-Альфа тетрагидрокортизол^до дозы дексаметазона:МассСк:24 часа:Моча:Колич:
Synonyms: Количественный Массовая скорость
tr-TRTurkish (Turkey)5-Alfa tetrahidrokortizol^önc dekzametazon dozu:KütlHz:24Sa:İdrar:Kant:
zh-CNChinese (China)5-Alpha 四氢皮质醇^在给予地塞米松之前:质量速率:24小时:尿液:定量型:
Synonyms: 1天;1日;24.0小时;一天;一日;二十四个小时;二十四小时 5 Alpha-四氢皮质甾醇 5 Alpha-四氢皮醇 5-A 四氢皮质醇;5-α 四氢皮质醇;5-alpha（α、A） 四氢皮质醇（THC、THF、四氢皮质甾醇、四氢皮醇） 5α-四氢皮质甾醇 5α-四氢皮质醇 5α-四氢皮醇 9α氟16甲基脱氢皮质甾醇;氟甲强的松龙;氟美松;甲氟烯索 THC;THF;四氢皮质甾醇;四氢皮醇 XXX刺激 - 在...之前 α 一剂物质 一剂药物 之前于剂量物质;之前于剂量药物;在剂量物质之前 之前于给予地塞米松 剂量物质 单位时间内的质量数;质量速率(单位时间) 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 尿;小便;下泉 阿尔法

Example Units

UnitSource
mg/(24.h)Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=57618-1