Version 2.80

Part Descriptions

LP97600-8   Procollagen type III.N-terminal propeptide
The amino terminals of type III procollagen peptide (P3NP) are extensions at the ends of the type III procollagen that are cleaved during synthesis and degradation of type III procollagen to make type III collagen. P3NP are released into extracellular fluid and a marker for collagen turnover. Increased levels of P3NP occur in conditions with excessive connective tissue repair, such as fibrosis, malignant and blood-related diseases. PMID: 16679477 Source: Regenstrief LOINC , PMID: 16679477

LP97600-8   Procollagen type III.N-terminal propeptide
A procollagen peptide contains an additional peptide sequence, termed the propeptide, at its amino and carboxy terminal ends. Collagen types I, II, III, IV and V are synthesized as precursor molecules called procollagens. Propeptides facilitate the winding of procollagen molecules into a triple-helix conformation within the endoplasmic reticulum. These propeptides are then cleaved from the collagen triple helix molecule during its secretion, after which the collagens polymerize into extracellular collagen fibrils. Thus, the amount of free propeptides directly correlates with collagen molecule synthesis. Procollagen Type I C-peptide (PIP) has also been extensively referenced in correlation studies between collagen levels and certain health disorders such as bone disease, alcoholic liver disease, liver cirrhosis and cirrhosis (Borrmann type IV) adenocarcinoma of the stomach. Source: Regenstrief Help

LP97600-8   Procollagen type III.N-terminal propeptide
Collagen types III and I are synthesized as procollagens with a small amino terminal and a larger carboxy terminal propeptide. Once secreted into the extracellular space, the propeptides are removed by specific endopeptidases, thus allowing integration of the rigid collagen triple helix into the growing fibril. The three-amino acid procollagen type III amino terminal peptide (PIIIP) formed during this process is released into the blood. The serum concentration of PIIIP has been proposed as a useful marker of collagen type III synthesis. Source: Regenstrief Help

Fully-Specified Name

Component
Procollagen type III.N-terminal propeptide
Property
ACnc
Time
Pt
System
Ser
Scale
Qn
Method

Additional Names

Long Common Name
Procollagen type III.N-terminal propeptide [Units/volume] in Serum
Short Name
Procollagen III.N-term propep Ser-aCnc
Display Name
Procollagen type III.N-terminal propeptide Qn (S)
Consumer Name Alpha Get Info
Procollagen Type III.N-terminal Propeptide, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.70 (MIN)
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Prokollagen Typ III.N-terminales Propeptid:Arbiträre Konzentration:Zeitpunkt:Serum:Quantitativ:
el-GR Greek (Greece) Προκολλαγόνο τύπου IΙΙ.N-τερματικό προπεπτίδιο:ACnc:Pt:Ορός:Qn:
Synonyms: ACnc N Type Προκολλαγόνο τύπου III Προκολλαγόνο τύπου IΙΙ.N-τερματικό προπεπτίδιο
es-ES Spanish (Spain) Péptido procolágeno tipo III N-Terminal:Concentración arbitraria:Punto temporal:Suero:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Propéptido Procolágeno tipo III.N-terminal:Concentración arbitraria:Punto temporal:Suero:Cuantitativo:
et-EE Estonian (Estonia) III tüüpi prokollageeni N-fragment:Acnc:Pt:S:Qn:
Synonyms: Juhuslik Kvantitatiivne Seerum
fr-CA French (Canada) Procollagène type III.N-terminal propeptide:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
fr-FR French (France) Procollagène type 3 propeptide N terminal:Arbitraire/Volume:Ponctuel:Sérum:Numérique:
fr-BE French (Belgium) Procollagen peptide.type 3 N-Terminal:Concentration arbitraire:Temps ponctuel:Sérum:Quantitatif:
it-IT Italian (Italy) Procollagene, peptide.tipo 3 N-Terminale:ACnc:Pt:Siero:Qn:
Synonyms: Chimica Concentrazione Arbitraria Peptide del procollagene di tipo 3 Peptide del procollagene di tipo 3 N-Terminale Punto nel tempo (episodio) Siero
nl-NL Dutch (Netherlands) procollageenpeptide.type 3 N-terminaal:eenheid/volume:moment:serum:kwantitatief:
Synonyms: soort
pt-BR Portuguese (Brazil) Peptídeo procolageno.tipo 3 N-Terminal:#N/A:Pt:Soro:Qn:
Synonyms: ; Procollagen Peptide.3 N-term; Procollagen Peptide3; Arbitrary concentration; Point in time; Random; Serum; SR; Quantitative; QNT; Quant; Quan; Pept; III; Chemistry
ru-RU Russian (Russian Federation) Проколлаген пептид.тип 3 N-Терминаль:ПроизвКонц:ТчкВрм:Сыв:Колич:
Synonyms: Количественный Пептид проколлагена III Произвольная концентрация Сыворотка Точка во времени;Момент
tr-TR Turkish (Turkey) Prokollajen peptid.tip 3 N-Terminal:SçKons:Zmlı:Ser:Kant:
zh-CN Chinese (China) 前胶原肽.III 型 N-末端:任意型浓度:时间点:血清:定量型:
Synonyms: 3 型前胶原肽 N-末端;3 型前胶原肽氨基末端;III 型前胶原肽 N-末端;III 型前胶原肽氨基末端;P3NP;PIIINP;前胶原肽.3 型 氨基末端;前胶原肽.3 型 N-末端;前胶原肽.III 型 氨基末端 3 型前胶原肽;3 型原骨胶原肽;3 型溶胶原肽;3 型酸溶原胶原蛋白肽;3 型酸溶胶原蛋白肽;III 型前胶原肽;III 型原骨胶原肽;III 型溶胶原肽;III 型酸溶原胶原蛋白肽;III 型酸溶胶原蛋白肽;前胶原肽.3 型;原骨胶原肽.3 型;原骨胶原肽.III 型;溶胶原肽.3 型;溶胶原肽.III 型;酸溶原胶原蛋白肽.3 型;酸溶原胶原蛋白肽.III 型;酸溶胶原蛋白肽.3 型;酸溶胶原蛋白肽.III 型 N 型 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 型 时刻;随机;随意;瞬间

Example Units

Unit Source
[arb'U]/mL Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=57756-9