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Term Description

Identifies an evening specimen when free cortisol is at its lowest point in a circadian cycle -often considered to be midnight. Some laboratories will call this "12AM (midnight)" specimen, but specimens in the range of 11PM to 1AM are acceptable. The trough time may have to be adjusted for patients on different work shifts because their circadian rhythms can shift with their sleeping time.

Part Descriptions

LP156504-5   PM trough specimen
Identifies an evening specimen when analyte is at its lowest point in a circadian cycle -often considered to be midnight. Some laboratories will call this "12AM (midnight)" specimen, but specimens in the range of 11PM to 1AM are acceptable. The trough time may have to be adjusted for patients on different work shifts because their circadian rhythms can shift with their sleeping time. Source: Regenstrief Help

LP29041-8   Cortisol.free
Cortisol is a glucocorticoid produced in the adrenal cortex. A synthetic version of this same chemical is called hydrocortisone and manufactured as medication. Cortisol is not to be confused with cortisone, a closely related compound with much less (PubChem calls it "inactive") biologic activity. Cortisone is also offered as a drug, and it is converted to cortisol (the active form) in the liver. They both have a circadian rhythm with peak in the AM (around 8AM) and trough in the evening (around midnight), but this shifts according to sleep habits (work shifts). The morning measurement, which should be high, is most useful for diagnosing Addison's disease (too little cortisol) and the evening measurement, which should be low, is the most useful for diagnosing Cushing's disease (too much cortisol). Salivary cortisol may be a more sensitive measure than serum or plasma. Source: Regenstrief Help

LOINC Names Get Info

Fully-Specified Name
Cortisol.free^PM trough specimen:MCnc:Pt:Ser/Plas:Qn:
Long Common Name
Cortisol Free [Mass/volume] in Serum or Plasma --PM trough specimen
Short Name
Cortis F PM SerPl-mCnc
Display Name
Cortisol Free PM trough specimen [Mass/Vol]
Consumer Name Alpha Get Info
Free cortisol PM Trough specimen, Blood

Part Model Get Info

  • Component
    Cortisol.free^PM trough specimen
    LP307389-9
    • Analyte
      Cortisol.free
      LP29041-8
      • Component Numerator
        Cortisol.free
        LP29041-8
        • Component Numerator Core
          Cortisol.free
          LP29041-8
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      PM trough specimen
      LP156504-5
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    MCnc
    LP6827-2
  • Time
    Pt
    LP6960-1
  • System
    Ser/Plas
    LP7576-4
    • System Core
      Ser/Plas
      LP7576-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    NULL
     

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.29
Last Updated
Version 2.73 (MIN)
Change Reason
To avoid two ways (PM and evening) of saying the same thing. We chose PM because it is shorter. 'Trough' clarifies that specimen is collected when cortisol is expected to be at the lowest level.
Order vs. Observation
Both
Common Test Rank Get Info
19144

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Kortizol.volný^Vzorek z odpoledního minima:Hmotnostní koncentrace:Časový bod:Sérum/plazma:Kvantitativní:
el-GRGreek (Greece)Κορτιζόλη.ελεύθερη^Δείγμα κατωφλίου μ.μ.:MCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: CHEM MCnc Pt Qn Δείγμα κατωφλίου μ.μ. ελάχιστα επίπεδα Κορτιζόλη Κορτιζόλη.ελεύθερη Ορός Ορός/Πλάσμα Πλάσμα
es-ESSpanish (Spain)Cortisol libre^PM muestra valle:Concentración de masa:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Cortisol. Libre ^ PM a través de la muestra:Concentración de masa:Punto temporal:Suero o Plasma:Cuantitativo:
fr-CAFrench (Canada)Cortisol.libre^Spécimen creux PM:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
fr-FRFrench (France)Cortisol libre^résiduel Soir:Masse/Volume:Ponctuel:Sérum/Plasma:Numérique:
fr-BEFrench (Belgium)Cortisol.libre^Spécimen PM minimal:Concentration de masse:Temps ponctuel:Sérum/Plasma:Quantitatif:
Synonyms: Echantillon. PM.minimal Minimum, nadir
it-ITItalian (Italy)Cortisolo.libero^campione minimo serale:MCnc:Pt:Siero/Plasma:Qn:
Synonyms: Chimica Concentrazione di Massa Cortisolo Libero Plasma Punto nel tempo (episodio) Siero Siero o Plasma valore minimo TDM
nl-NLDutch (Netherlands)cortisol.vrij^middag-dalspiegelmonster:massa/volume:moment:serum of plasma:kwantitatief:
pt-BRPortuguese (Brazil)Cortisol.livre^amostra noturna:#N/A:Pt:Sor/Plas:Qn:
Synonyms: ; Cortis F; Coritsol; Compound F; 17-Hydroxycorticosterone; PM; Mass concentration; Level; Point in time; Random; SerPl; SerPlas; SerP; Serum; SR; Plasma; Pl; Plsm; Quantitative; QNT; Quant; Quan; Spec; FR; Non-protein bound; Chemistry
ru-RURussian (Russian Federation)Кортизол.свободный^Вечерний минимальный образец:МассКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая концентрация минимум концентрации Плазма Провал концетрации кортизола наблюдающийся с 23:00 до 1:00 Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TRTurkish (Turkey)Kortizol.serb^Öğleden sonra örneği:KütlKons:Zmlı:Ser/Plaz:Kant:
Synonyms: çukur düzey
zh-CNChinese (China)皮质醇.游离型^晚上波谷标本:质量浓度:时间点:血清/血浆:定量型:
Synonyms: 17-羟皮质甾酮;17-羟皮质酮;化合物 F;可的索;氢化可的松;皮质甾醇;考的索 一剂药物的初始剂量;初始剂量;剂量药物的初始剂量;前剂量;曲线上的最小值;最低点;本底剂量;治疗药物监测 - 波谷;预剂量 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 晚上（晚间）波谷（谷值、低谷、最小值、最低点）标本（样本、样品、试样） 标本（样本、样品、试样） 样品 样本 水平;浓度;质量浓度(单位体积) 游离 皮质醇（可的索、考的索）.游离型;游离型皮质醇;游离皮质醇;皮质醇.游离 血清或血浆 试样 非蛋白结合型 非蛋白质结合型

Example Units

UnitSource
ug/dLExample UCUM Units

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=57825-2