58357-5

Amphetamine/Creatinine [Mass Ratio] in Urine

Active

Part Descriptions

LP18868-7 Amphetamine
Amphetamine (AMPH) is a drug that stimulates both the central and peripheral nervous systems and is used to treat attention-deficit/hyperactivity disorder, narcolepsy and obesity. PMID: 17209801 AMPH increases extracellular monoamine neurotransmitters in the brain including dopamine, serotonin and norepinephrine. AMPH promotes presynaptic release of the neurotransmitters rather than blocking their re-uptake. Physiological responses to AMPH use include increased blood pressure, increased heart rate, increased body temperature, relaxed bronchial muscle and depressed appetite. Abuse of AMPH can cause powerful psychological dependence, tolerance, mild physical dependence associated with tachycardia, restlessness, irritability, insomnia, personality changes and an intense form of chronic intoxication psychosis similar to schizophrenia. Long-term users of AMPH can experience depression, impaired memory and motor skills most likely due to a drop in dopamine transporters and damage to dopaminergic and serotonergic neurons. Excretion of AMPH is in the urine and the rate of elimination is dependent on the pH of the urine. Urine with an alkaline pH has an excretion rate of 18-34 hours while that of acid urine is 7-14 hours.(Tietz Fundamentals of Clinical Chemistry and Molecular Diagnostics, Seventh Edition; Carl A. Burtis; David E. Bruns) Source: Regenstrief LOINC

LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

LOINC Names Get Info

Fully-Specified Name: Amphetamine/Creatinine:MRto:Pt:Urine:Qn:
Long Common Name: Amphetamine/Creatinine [Mass Ratio] in Urine
Short Name: Amphet/Creat Ur
Display Name: Amphetamine/Creatinine (U) [Mass ratio]
Consumer Name Alpha Get Info: Amphetamine/Creatinine, Urine

Part Model Get Info

Component
Amphetamine/Creatinine
LP284971-1
- Analyte
  Amphetamine/Creatinine
  LP284971-1
  - Component Numerator
    Amphetamine
    LP18868-7
    - Component Numerator Core
      Amphetamine
      LP18868-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Creatinine
    LP32035-5
    - Component Denominator Core
      Creatinine
      LP32035-5
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
MRto
LP6834-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Urine
LP7681-2
- System Core
  Urine
  LP7681-2
- Super System
  NULL
Scale
Qn
LP7753-9
Method
NULL

Basic Attributes

Class: DRUG/TOX
Type: Laboratory
First Released: Version 2.30
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 2328

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Amfetamin/kreatinin:Hmotnostní poměr:Časový bod:Moč:Kvantitativní:
el-GR	Greek (Greece)	Αμφεταμίνη/Κρεατινίνη:MRto:Pt:Ούρα:Qn: Synonyms: DRUG/TOX MRto Pt Qn Αμφεταμίνη Κρεατινίνη Ούρα
es-ES	Spanish (Spain)	Anfetamina/Creatinina:Relacion de Masa:Punto temporal:Orina:Qn: Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Anfetamina / Creatinina:Relación de masa:Punto temporal:Orina:Cuantitativo:
et-EE	Estonian (Estonia)	Amfetamiin/kreatiniin:MRto:Pt:U:Qn: Synonyms: Juhuslik Kvantitatiivne Uriin
fr-CA	French (Canada)	Amphétamine/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif:
fr-FR	French (France)	Amphétamine/créatinine:Masse ratio:Ponctuel:Urine:Numérique:
fr-BE	French (Belgium)	Amphétamine/Créatinine:Ratio de masse:Temps ponctuel:Urine:Quantitatif: Synonyms: Rapport de masse
it-IT	Italian (Italy)	Anfetamina/Creatinina:MRto:Pt:Urine:Qn: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa
nl-NL	Dutch (Netherlands)	amfetamine/creatinine:massaverhouding:moment:urine:kwantitatief: Synonyms: kreatinine
pt-BR	Portuguese (Brazil)	Anfetamina/Creatinina:#N/A:Pt:Urina:Qn: Synonyms: ; Amphet; Ampht; Amphetam; Amph; Amphetamines; Speed; Creat; CR; mRto; Mass concentration ratio; Point in time; Random; Ur; UR; Urn; UA; Quantitative; QNT; Quant; Quan; Drugs; DRUG/TOXICOLOGY; DRUG/TOXICOLOGY; UCr
ru-RU	Russian (Russian Federation)	Амфетамин/Креатинин:МассОтн:ТчкВрм:Моча:Колич: Synonyms: Количественный Масс отношение Точка во времени;Момент
tr-TR	Turkish (Turkey)	Amfetamin/Kreatinin:KütlOr:Zmlı:İdrar:Kant:
zh-CN	Chinese (China)	苯丙胺/肌酐:质量比率:时间点:尿液:定量型: Synonyms: C9H13N;安非他明;苯异丙胺;苯齐巨林 CR;Creat;肌氨酸酐;肌酸内酰胺;肌酸酐 UCr 可用数量表示的;定量性;数值型;数量型;连续数值型标尺尿;小便;下泉尿液肌酐尿液肌酸酐尿肌酸酐时刻;随机;随意;瞬间来自于同一体系的两种分析物的质量之比;质量比毒品毒品类肌酸内酰胺药品类药物药物/毒理学;药物/毒理学试验;药物毒理学试验;药物毒理学试验类药物类

Example Units

Unit	Source
ug/g{creat}	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.