Version 2.76

Part Description

LP14239-5   Influenza virus A
Influenza viruses, from the family Orthomyxoviridae, are enveloped negative-strand RNA viruses with segmented genomes containing seven to eight gene segments. Of the five genera in the family, only influenza A virus (IAV), influenza B and C are medically relevant to humans. Aquatic birds harboring avian IAV are the likely natural reservoir for all known IAV subtypes and are probably the original source of all human pandemic IAV strains. IAV maintained in wild birds have been associated with stable host switch events to novel hosts, including most often to domestic poultry but also to horses, swine, toothed whales and humans. The influenza virus life cycle begins with the binding of viral HA to host cell receptors. Endocytosis and HA-mediated fusion of the viral and cellular membranes occurs. Viral ribonucleoprotein complexes are released into the cytoplasm, travel to the nucleus, then are replicated and transcribed by the viral polymerase complex. The new viruses are formed and bud when the newly formed ribonucleicprotein complexes and structural proteins reach the plasma membrane. Further research is needed to better understand how IAVs switch hosts and the viral genetic changes that underlie human adaptation. IAV causes respiratory infections in humans ranging from asymptomatic to fatal. Pandemics are attributed to "novel" viruses which possess a viral hemagglutinin (HA) to which humans do not have immunity. PMID: 20542248 ] PMID: 25812763
Influenza viruses A and B are single-stranded RNA enveloped viruses belonging to the Orthomyxoviridae family. The symptoms of infection of Influenza A and B include fever, cough, sore throat, rhinorrhea, nasal congestion, headache, myalgia and malaise. Some patients may experience gastrointestinal symptoms including watery diarrhea, vomiting and abdominal pain. The influenza viruses spread rapidly in enclosed spaces with a documented rate of infection of 70% following a common source of exposure. Infection occurs in the respiratory epithelium in both the upper and lower respiratory tract, and the virus can be found in many specimen types, including nasal aspirates, nasal or nasopharyngeal swabs, throat swabs, sputum and tracheal aspirates. When infection rates reach epidemic proportions, hospitalization of children and elderly patients rises as does the mortality rates of elderly patients.(Manual of Clinical Microbiology, 11th edition, James H. Jorgensen; Karen C. Carroll; Guido Funke; Michael A Pfaller; Marie Louise Landry; Sandra S. Richter; David W. Warnock) Source: Regenstrief LOINC

Fully-Specified Name

Component
Influenza virus A Ag
Property
PrThr
Time
Pt
System
XXX
Scale
Ord
Method
IF

Additional Names

Short Name
FLUAV Ag Spec Ql IF
Display Name
FLUAV Ag IF Ql (Specimen)
Consumer Name Alpha Get Info
Influenza A (Flu A) antigen, Specimen

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0
Last Updated
Version 2.73
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both
Common Test Rank Get Info
2088

Member of these Groups Get Info

LOINC Group Group Name
LG32757-3 Influenza virus

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Influenza-Virus A Ag:Nachweis oder Schwellenwert:Zeitpunkt:XXX:Ordinal:Immunfluoreszenztest
es-AR Spanish (Argentina) [antígeno de] virus influenza A [Ag]:concentración arbitraria:punto en el tiempo:XXX:ordinal:inmunofluorescencia
es-MX Spanish (Mexico) Virus de la influenza A Ag:Presencia o umbral:Punto temporal:XXX:Ordinal:Inmunofluorescencia (IF)
es-ES Spanish (Spain) Virus Influenza A Antígeno:PrThr:Punto temporal:XXX:Ord:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) A-gripi viirus antigeen:PrThr:Pt:XXX:Ord:IF
Synonyms: Järgarvuline Juhuslik Täpsustamata materjal
fr-FR French (France) Influenza virus A Ag:Présence/Seuil:Ponctuel:Milieux divers:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Virus de l'influenza A Ag:PrThr:Temps ponctuel:XXX:Ordinal:Immunofluorescence
Synonyms: Antigène FLU A virus FLU virus
fr-CA French (Canada) Virus de l'influenza A , Ag:Présence-Seuil:Temps ponctuel:XXX:Ordinal:Immunofluorescence
it-IT Italian (Italy) Influenza A, virus , Ag:PrThr:Pt:XXX:Ord:IF
Synonyms: Immunofluorescenza (IF) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Virus dell''influenza Virus dell''influenza A
ko-KR Korean (Korea, Republic Of) A형 인플루엔자 바이러스 항원:임의농도:검사시점:XXX:순위척도:면역형광
nl-NL Dutch (Netherlands) Influenzavirus A Ag:aanwezigheid:moment:XXX:ordinaal:immunofluorescentie
Synonyms: antigeen IF
pl-PL Polish (Poland) Wirus grypy A Ag:granica wykrywalności:punkt w czasie:XXX:półilościowy:immunofluorescencja
Synonyms: Antygen wirusa grypy typ A Wirus grypy Wirus grypy typ A
pt-BR Portuguese (Brazil) Influenza vírus A Ag:ACnc:Pt:XXX:Ord:Imunofluorescência
Synonyms: ; FLUAV; Avian influenza; Fowl plague; Influenza A virus; FLUA; Bird flu; FLUV; Influ; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Ql; Ordinal; QL; Qualitative; Qual; Screen; ACIF; FA; Fluorescent antibody; Immune fluorescence; Fluoresent; Immunoflour; Immunofluor; Immunofluorescence; IFA; Time Resolved Fluorescence; Anticomplement Immunofluorescence; TRF; Antigen; Antigens; Microbiology; DFA
ru-RU Russian (Russian Federation) Грипп вирус А Аг:PrThr:ТчкВрм:XXX:Пор:ИФ
Synonyms: Иммунофлюоресценция (ИФ) Порядковый Точка во времени;Момент
tr-TR Turkish (Turkey) İnfluenza virüsü A Ag:MevcEşik:Zmlı:XXX:Srl:IF
Synonyms: Antijen İmmünflorerans Mevcut
uk-UA Ukrainian (Ukraine) Вірус грипу А, Антиген:Наявність або Поріг:МоментЧасу:ХХХ:Порядково:Імунофлуоресценція
Synonyms: ACIF; Anticomplement Immunofluorescence; Antigen; Antigens; Avian influenza; Bird flu; DFA; FA; FLUA; FLUAV; Fluorescent antibody; Fluoresent; FLUV; Fowl plague; ID; IFA; Immune fluorescence; Immunoflour; Immunofluor; Immunofluorescence; Infectious Disease; InfectiousDisease; Influ; Influenza A; Influenza A virus; Microbiology; Misc; Miscellaneous; Ordinal; Other; Point in time; PR; QL; Qual; Qualitative; Random; Screen; Spec; Time Resolved Fluorescence; To be specified in another part of the message; TRF; UniversalLabOrders; Unspecified
zh-CN Chinese (China) 流感病毒 A 型 抗原:存在情况或阈值:时间点:XXX:序数型:免疫荧光法
Synonyms: A 型 A 型抗原 A 型流感;A 型流感病毒;FLUA;FLUAV;家禽鼠疫;流感 A;流感 A 型;流感甲型;流感病毒甲型;甲型流感;甲型流感病毒;瘟疫;禽流感;禽流行性感冒;禽疫;鸡瘟 A 型流感病毒 Ag A 型流感病毒抗原 Ag Ag IF DFA FLUA Ag FLUA 抗原 FLUAV Ag FLUAV 抗原 FLUV;Influ;列性感冒病毒;流行性感冒病毒 IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项 传染毒;传染毒素;滤过性病原体;病毒类;过滤性病原体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 微生物学;微生物学试验;微生物学试验(培养、DNA、抗原及抗体) 抗原免疫荧光检测 抗原免疫荧光测定 时刻;随机;随意;瞬间 流感病毒 A 型 Ag 流感病毒甲型 Ag 流感病毒甲型抗原 甲型流感病毒 Ag 甲型流感病毒抗原 直接免疫荧光分析 直接免疫荧光检测 直接免疫荧光测定

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