Version 2.73

59262-6Leukocyte esterase [Presence] in Cerebral spinal fluid by Test stripActive

Term Description

Used to screen CSF for possible menigitis.
Source: Regenstrief LOINC

Part Descriptions

LP15701-3   Leukocyte esterase
Leukocyte esterase (LE) is an enzyme contained in WBCs. In fluids that are usually cell "free", detection of this enzyme indicates the presence of a significant number of WBCs which can signal infection or inflammation. In urine, this test is used to detect white blood cells and other abnormalities associated with infections. White blood cells in the urine usually indicate a urinary tract infection (UTI). The LE test detects esterase, an enzyme released by white blood cells. Testing for LE is a routine part of the urine dip stick, and helps to diagnose urinary tract infections. Positive test results are clinically significant. The LE test is also used to screen for gonorrhea and for amniotic fluid infections. The combination of the LE test with the urinary nitrite test provides an excellent tool for the presence of a UTI. A urine sample that tests positive for both nitrite and leukocyte esterase should be cultured for pathogenic bacteria. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Leukocyte esterase

LP20670-3   Leukocyte
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Regenstrief LOINC, Esterase (Wikipedia)

Fully-Specified Name

Leukocyte esterase
Test strip

Additional Names

Short Name
Leukocyte esterase CSF Ql Strip
Display Name
Leukocyte esterase Test strip Ql (CSF)
Consumer Name Alpha
Leukocyte esterase, Spinal fluid

Example Answer List LL360-9

Source: Regenstrief Institute

Answer Code Score Answer ID
Positive Copyright http://snomed.info/sct ID:10828004 Positive (qualifier value) LA6576-8
Negative Copyright http://snomed.info/sct ID:260385009 Negative (qualifier value) LA6577-6

Basic Attributes

First Released
Version 2.32
Last Updated
Version 2.70
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation

Language Variants Get Info

zh-CNChinese (China)
nl-NLDutch (Netherlands)
leukocytenesterase:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:teststrip
fr-BEFrench (Belgium)
Estérase leucocytaire:PrThr:Temps ponctuel:LCR:Ordinal:Bâtonnet diagnostique
fr-CAFrench (Canada)
Estérase leucocytaire:Présence-Seuil:Temps ponctuel:LCR:Ordinal:Bâtonnet diagnostique
fr-FRFrench (France)
Leucocyte estérase:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Bandelette réactive
it-ITItalian (Italy)
Esterasi leucocitaria:PrThr:Pt:LCS:Ord:Test strip
pt-BRPortuguese (Brazil)
Leucócito esterase::Pt:LCR:Ord:Fita reagente
ru-RURussian (Russian Federation)
Лейкоцитарная эстераза:PrThr:ТчкВрм:ЦСЖ:Пор:Тест-полоска
es-MXSpanish (Mexico)
Esterasa de leucocitos:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Tira de prueba
es-ESSpanish (Spain)
Esterasa leucocitaria:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:Tira reactiva
tr-TRTurkish (Turkey)
Lökosit esteraz:MevcEşik:Zmlı:BOS:Srl:Test çubuğu

LOINC FHIR® API Example - CodeSystem Request Get Info