5970-9
Plasminogen [Units/volume] in Platelet poor plasma by Chromogenic method
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Part Descriptions
LP16482-9 Plasminogen
Plasmin, an enzyme that degrades many blood plasma proteins (most notably fibrin clots) is released as a zymogen called plasminogen (PLG) from the liver into the systemic circulation. Two major glycoforms of plasminogen are present in humans - type I plasminogen contains two glycosylation moieties (N-linked to N289 and O-linked to T346), whereas type II plasmingen contains only a single O-linked sugar (O-linked to T346). Type II plasminogen is preferentially recruited to the cell surface over the type I glycoform. Conversely, type I plasminogen appears more readily recruited to blood clots.
Plasminogen deficiency in mice leads to defective liver repair, defective wound healing, reproductive abnormalities.
In human, a rare disorder called plasminogen deficiency type I (Online 'Mendelian Inheritance in Man' [OMIM: 217090] is caused by mutations of the PLG gene and is often manifested by ligneous conjunctivitis.
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Source: Wikipedia, Plasminogen (Wikipedia)
LP16482-9 Plasminogen
Precursor of fibrinolysin (plasmin). It is a single-chain beta-globulin of molecular weight 80-90,000 found mostly in association with fibrinogen in plasma; plasminogen activators change it to fibrinolysin. It is used in wound debriding and has been investigated as a thrombolytic agent.
Source: National Library of Medicine, MeSH 2006
Fully-Specified Name
- Component
- Plasminogen
- Property
- ACnc
- Time
- Pt
- System
- PPP
- Scale
- Qn
- Method
- Chromo
Additional Names
- Short Name
- PLG PPP Chro-aCnc
- Display Name
- Plasminogen Chromogenic method Qn (PPP)
- Consumer Name Alpha Get Info
- Plasminogen, Blood
Basic Attributes
- Class
- COAG
- Type
- Laboratory
- First Released
- Version 1.0d
- Last Updated
- Version 2.73
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 6677
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| de-DE | German (Germany) | Plasminogen: |
| es-AR | Spanish (Argentina) | plasminógeno: |
| es-ES | Spanish (Spain) | Plasminógeno: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Plasminógeno: |
| et-EE | Estonian (Estonia) | Plasminogeen: Synonyms: Juhuslik Kvantitatiivne Trombotsüütidevaene plasma |
| fr-CA | French (Canada) | Plasminogène: |
| fr-FR | French (France) | Plasminogène: |
| fr-BE | French (Belgium) | Plasminogène: |
| it-IT | Italian (Italy) | Plasminogeno: Synonyms: Concentrazione Arbitraria Cromogenico (Enzima) Plasma povero di piastrine Punto nel tempo (episodio) Studio di coagulazione |
| ko-KR | Korean (Korea, Republic Of) | 플라스미노겐: |
| nl-NL | Dutch (Netherlands) | plasminogeen: Synonyms: coagulatiemethode |
| pt-BR | Portuguese (Brazil) | Plasminogênio: Synonyms: ; |
| ru-RU | Russian (Russian Federation) | Плазминоген: Synonyms: Количественный Обеднённая пластинками плазма; |
| tr-TR | Turkish (Turkey) | Plazminojen: |
| zh-CN | Chinese (China) | 纤溶酶原: Synonyms: PLG; |
Example Units
| Unit | Source |
|---|---|
| CTA u/mL | REGENSTRIEF |
| U/mL | eCHN |
| {CTA'U}/mL | Example UCUM Units |
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