59817-7

Uroporphyrin 1 isomer/Creatinine [Molar ratio] in 24 hour Urine

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Part Descriptions

LP18653-3   Uroporphyrin 1 isomer
Uroporphyrin is the porphyrin produced by oxidation of the methylene bridges in uroporphyrinogen. They have four acetic acid and four propionic acid side chains attached to the pyrrole rings. Uroporphyrinogen I and III is formed from polypyrryl methane in the presence of uroporphyrinogen III cosynthetase and uroporphyrin I synthetase, respectively. They can yield uroporphyrins by autooxidation or coproporphyrinogens by decarboxylation. Excessive amounts of uroporphyrin I are excreted in congenital erythropoietic porphyria, and both types I and III are excreted in porphyria cutanea tarda. Uroporphyrin I and III are the most common isomers. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Uroporphyrin I

LP32035-5   Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas. Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Creatinine

Fully-Specified Name

Component

Uroporphyrin 1 isomer/Creatinine

Property

SRto

Time

24H

System

Urine

Scale

Qn

Method

Additional Names

Short Name

Uropor1/Creat 24h Ur-sRto

Display Name

Uroporphyrin 1 isomer/Creatinine (24H U) [Molar ratio]

Consumer Name Alpha Get Info

Uroporphyrin 1 isomer/Creatinine, Urine

Basic Attributes

Class

CHEM

Type

Laboratory

First Released

Version 2.32

Last Updated

Version 2.70

Order vs. Observation

Observation

Member of these Groups Get Info

Language Variants Get Info

Related Names

• 1 day
• 24 hours
• 24HR
• Chemistry
• CR
• Crea
• Creat
• i
• Isom
• Octacarboxyl porphyrin
• Octacarboxylporphyrin
• Octacarboxyphyrin
• Porphyria
• Porphyria cutanea tarda
• QNT
• Quan
• Quant
• Quantitative
• Scrto
• Substance concentration ratio
• Substance ratio
• UA
• UCr
• UR
• Urn
• Urophorph
• Uropor1
• Uroporphyrin I

Example Units

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