60019-7

Lactate dehydrogenase [Enzymatic activity/volume] in Pericardial fluid by Lactate to pyruvate reaction

Active

Part Descriptions

LP15033-1 Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1 Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Lactate dehydrogenase:CCnc:Pt:Pericard fld:Qn:Reaction: lactate to pyruvate
Long Common Name: Lactate dehydrogenase [Enzymatic activity/volume] in Pericardial fluid by Lactate to pyruvate reaction
Short Name: LDH Pcar L to P-cCnc
Display Name: LDH Lactate to pyruvate reaction (Pericard fld) [Catalytic activity/Vol]
Consumer Name Alpha Get Info: Lactate Dehydrogenase (LDH), Pericardial fluid

Part Model Get Info

Component
Lactate dehydrogenase
LP15033-1
- Analyte
  Lactate dehydrogenase
  LP15033-1
  - Component Numerator
    Lactate dehydrogenase
    LP15033-1
    - Component Numerator Core
      Lactate dehydrogenase
      LP15033-1
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
CCnc
LP6789-4
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Pericard fld
LP7466-8
- System Core
  Pericard fld
  LP7466-8
- Super System
  NULL
Scale
Qn
LP7753-9
Method
Reaction: lactate to pyruvate
LP6479-2

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 2.34
Last Updated: Version 2.73 (MIN)
Order vs. Observation: Both
Common Test Rank Get Info: 16476

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Laktátdehydrogenáza:Katalytická koncentrace:Časový bod:Perikardiální tekutina:Kvantitativní:Reakce laktát na pyruvát
de-DE	German (Germany)	Lactatdehydrogenase:Katalytische Konzentration:Zeitpunkt:Perikardflüssigkeit:Quantitativ:Reaktion: Lactat zu Pyruvat Synonyms: LDH
el-GR	Greek (Greece)	Γαλακτική αφυδρογονάση:CCnc:Pt:Περικαρδιακό υγρό:Qn:Αντίδραση: γαλακτικό προς πυροσταφυλικό Synonyms: CCnc CHEM Pt Qn Αντίδραση: γαλακτικό προς πυροσταφυλικό Γαλακτική αφυδρογονάση Γαλακτικό οξύ Περικαρδιακό υγρό
es-ES	Spanish (Spain)	Lactato deshidrogenasa:Concentración Catalítica:Punto temporal:Fluido pericárdico:Qn:Reacción - lactato piruvato Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Lactato deshidrogenasa:Concentración catalítica:Punto temporal:Líquido pericárdico:Cuantitativo:Reacción - lactato a piruvato
fr-CA	French (Canada)	Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Liquide péricardique:Quantitatif:Réaction: lactate en pyruvate
fr-FR	French (France)	Lactate déshydrogénase:Catalytique/Volume:Ponctuel:Liquide péricardique:Numérique:Réaction : Lactate vers Pyruvate
fr-BE	French (Belgium)	Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Liquide péricardique:Quantitatif:Réaction: lactate en pyruvate Synonyms: LDH
it-IT	Italian (Italy)	Lattato deidrogenasi:CCnC:Pt:Liquido pericardico:Qn:Reazione: lattato in piruvato Synonyms: Chimica Concentrazione Catalitica Liquido pericardico Punto nel tempo (episodio) Reazione- lattato in piruvato
nl-NL	Dutch (Netherlands)	lactaatdehydrogenase:enzymatische activiteit/volume:moment:pericardvocht:kwantitatief:reactie: lactaat naar pyruvaat
pl-PL	Polish (Poland)	Dehydrogenaza mleczanowa:stężenie katalityczne:punkt w czasie:płyn osierdziowy:ilościowy:reakcja L-P, mleczan-pirogronian
tr-TR	Turkish (Turkey)	Laktat dehidrojenaz:KtlKons:Zmlı:Perikard sv:Kant:Reaksiyon: laktat tan piruvat a
zh-CN	Chinese (China)	乳酸脱氢酶:催化浓度:时间点:心包液:定量型:反应: 乳酸至丙酮酸 Synonyms: 2-羟基-丙酸;Lact;L-乳酸 L.D.H;LD;LDH;L-乳酸脱氢酶 React Rxn 乳酸 - 丙酮酸转化法;乳酸 -> 丙酮酸转化法;乳酸转化为丙酮酸的反应;反应: 乳酸 - 丙酮酸;反应: 乳酸 -> 丙酮酸催化浓度(单位体积);单位体积内酶的单位数化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类去氢酶可用数量表示的;定量性;数值型;数量型;连续数值型标尺心包积液;心包腔积液时刻;随机;随意;瞬间

Example Units

Unit	Source
U/L	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.