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Part Descriptions

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH) is an enzyme (EC 1.1.1.27) present in a wide variety of organisms, including plants and animals. It catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD+. As it can also catalyze the oxidation of hydroxybutyrate, it is occasionally called hydroxybutyrate dehydrogenase (HBD). Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, D-lactate (Wikipedia)

LP15033-1   Lactate dehydrogenase
Lactate dehydrogenase (LDH, or also called LD) is an oxidoreductase (LD: EC 1.1.1.27) and is the most important clinically of several dehydrogenases occurring in human serum. LDH catalyses the interconversion of pyruvate and lactate with concomitant interconversion of NADH and NAD. When disease, injury, or toxic material damages tissues, cells release LDH into the bloodstream. Since LDH is a fairly stable enzyme, it has been widely used to evaluate the presence of damage and toxicity of tissue and cells. LDH is cytoplasmic in its cellular location and in any one tissue is composed of one or two of five possible isoenzymes. While many of its clinical applications involve quantification of one or more specific serum isoenzymes, an estimate of total LDH is usually required. Lactate dehydrogenase catalyzes the reversible reaction: L-lactate + NAD <--> pyruvate + NADH. Testing methods either measure the increase in NADH produced in the lactate-to-pyruvate reaction or the decrease in NADH produced in the pyruvate-to-lactate reaction. PMID: 3882046. Reference ranges are highly method dependent. The pyruvate-to-lactate reaction is preferred theoretically because the equilibrium constant is large and the rate for any amount of enzyme is 2-3 times faster, thus smaller sample and shorter observation periods are needed. Disadvantages of the pyruvate-to-lactate reaction are loss of linearity as compared with the lactate-to-pyruvate reaction, and greater substrate inhibition of the enzyme. [Tietz Fourth Edition] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name
Lactate dehydrogenase:CCnc:Pt:Plr fld:Qn:Reaction: pyruvate to lactate
Long Common Name
Lactate dehydrogenase [Enzymatic activity/volume] in Pleural fluid by Pyruvate to lactate reaction
Short Name
LDH Plr P to L-cCnc
Display Name
LDH Pyruvate to lactate reaction (Pleur fld) [Catalytic activity/Vol]
Consumer Name Alpha Get Info
Lactate Dehydrogenase (LDH), Pleural fluid

Part Model Get Info

  • Component
    Lactate dehydrogenase
    LP15033-1
    • Analyte
      Lactate dehydrogenase
      LP15033-1
      • Component Numerator
        Lactate dehydrogenase
        LP15033-1
        • Component Numerator Core
          Lactate dehydrogenase
          LP15033-1
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    CCnc
    LP6789-4
  • Time
    Pt
    LP6960-1
  • System
    Plr fld
    LP7486-6
    • System Core
      Plr fld
      LP7486-6
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    Reaction: pyruvate to lactate
    LP6480-0

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.34
Last Updated
Version 2.73 (MIN)
Order vs. Observation
Both
Common Test Rank Get Info
7738

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Laktátdehydrogenáza:Katalytická koncentrace:Časový bod:Pleurální tekutina:Kvantitativní:Reakce pyruvát na laktát
de-DEGerman (Germany)Lactatdehydrogenase:Katalytische Konzentration:Zeitpunkt:Pleuraflüssigkeit:Quantitativ:Reaktion: Pyruvat zu Lactat
Synonyms: LDH
el-GRGreek (Greece)Γαλακτική αφυδρογονάση:CCnc:Pt:Υπεζωκοτικό υγρό:Qn:Αντίδραση: πυροσταφυλικό προς γαλακτικό
Synonyms: CCnc CHEM Pt Qn Αντίδραση: πυροσταφυλικό προς γαλακτικό Γαλακτική αφυδρογονάση Γαλακτικό οξύ Υπεζωκοτικό υγρό
es-ESSpanish (Spain)Lactato deshidrogenasa:Concentración Catalítica:Punto temporal:Líquido pleural:Qn:Reacción - piruvato lactato
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Lactato deshidrogenasa:Concentración catalítica:Punto temporal:Líquido pleural:Cuantitativo:Reacción - piruvato a lactato
fr-CAFrench (Canada)Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Liquide pleural:Quantitatif:Réaction: pyruvate en lactate
fr-FRFrench (France)Lactate déshydrogénase:Catalytique/Volume:Ponctuel:Liquide pleural:Numérique:Réaction : Pyruvate vers Lactate
fr-BEFrench (Belgium)Lactate déshydrogénase:Concentration catalytique:Temps ponctuel:Liquide pleural:Quantitatif:Réaction: pyruvate en lactate
Synonyms: LDH
it-ITItalian (Italy)Lattato deidrogenasi:CCnC:Pt:Liquido pleurico:Qn:Reazione: piruvato in lattato
Synonyms: Chimica Concentrazione Catalitica Liquido pleurico Punto nel tempo (episodio) Reazione -piruvato in lattato
nl-NLDutch (Netherlands)lactaatdehydrogenase:enzymatische activiteit/volume:moment:pleuravocht:kwantitatief:reactie: pyruvaat naar lactaat
pl-PLPolish (Poland)Dehydrogenaza mleczanowa:stężenie katalityczne:punkt w czasie:płyn opłucnowy:ilościowy:reakcja P-L, pirogronian-mleczan
tr-TRTurkish (Turkey)Laktat dehidrojenaz:KtlKons:Zmlı:Plvr sv:Kant:Reaksiyon: piruvat tan laktat a
zh-CNChinese (China)乳酸脱氢酶:催化浓度:时间点:胸膜液:定量型:反应: 丙酮酸至乳酸
Synonyms: 2-羟基-丙酸;Lact;L-乳酸 L.D.H;LD;LDH;L-乳酸脱氢酶 React Rxn 丙酮酸 - 乳酸转化法;丙酮酸 -> 乳酸转化法;丙酮酸转化为乳酸的反应;反应: 丙酮酸 - 乳酸;反应: 丙酮酸 -> 乳酸 催化浓度(单位体积);单位体积内酶的单位数 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 去氢酶 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 时刻;随机;随意;瞬间 胸腔积液;胸水;胸膜穿刺液;胸膜腔积水;胸膜腔积液

Example Units

UnitSource
U/LExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=60021-3