61414-9
Doxepin/Creatinine [Mass Ratio] in Urine
Active
Part Descriptions
LP14717-0 Doxepin
Doxepin is a dibenzoxepin tricyclic compound. It displays a range of pharmacological actions including maintaining adrenergic innervation. Its mechanism of action is not fully understood, but it appears to block reuptake of monoaminergic neurotransmitters into presynaptic terminals. It also possesses anticholinergic activity and modulates antagonism of histamine H(1)- and H(2)-receptors.
Source: National Library of Medicine, MeSH 2006
LP14717-0 Doxepin
Doxepin is indicated for the short-term (up to 8 days) topical treatment of moderate pruritus in adult patients with eczematous dermatitis. E.g., atopic dermatitis and lichen simplex chronicus. Once absorbed into the systemic circulation, doxepin undergoes hepatic metabolism that results in the conversion to the pharmacologically active metabolite, desmethyldoxepin. The parent compound and its metabolite also undergo glucuronidiation.
Source: Regenstrief Institute
LP32035-5 Creatinine
Creatinine or creatine anhydride, is a breakdown product of creatine phosphate in muscle. The loss of water molecule from creatine results in the formation of creatinine. It is transferred to the kidneys by blood plasma, whereupon it is eliminated by glomular filtration and partial tubular excretion. Creatinine is usually produced at a fairly constant rate and measuring its serum level is a simple test. A rise in blood creatinine levels is observed only with marked damage to functioning nephrons; therefore this test is not suitable for detecting early kidney disease. Creatine and creatinine are metabolized in the kidneys, muscle, liver and pancreas.
Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.)
Source: Human Metabolome Database, Creatinine
Fully-Specified Name
- Component
- Doxepin/Creatinine
- Property
- MRto
- Time
- Pt
- System
- Urine
- Scale
- Qn
- Method
Additional Names
- Short Name
- Doxepin/Creat Ur
- Display Name
- Doxepin/Creatinine (U) [Mass ratio]
- Consumer Name Alpha Get Info
- Doxepin/Creatinine, Urine
Basic Attributes
- Class
- DRUG/TOX
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.70
- Order vs. Observation
- Both
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Doxepina/Creatinina: Synonyms: Cuantitativo |
es-MX | Spanish (Mexico) | Doxepina / Creatinina: |
et-EE | Estonian (Estonia) | Doksepiin/kreatiniin: Synonyms: Juhuslik Kvantitatiivne Uriin |
fr-CA | French (Canada) | Doxépine/Créatinine: |
fr-FR | French (France) | Doxépine/créatinine: |
fr-BE | French (Belgium) | Doxépine/Créatinine: Synonyms: Rapport de masse |
it-IT | Italian (Italy) | Doxepina/Creatinina: Synonyms: Livelli farmacologici e tossicologia Punto nel tempo (episodio) Rapporto di Massa |
nl-NL | Dutch (Netherlands) | doxepine/creatinine: Synonyms: kreatinine |
pt-BR | Portuguese (Brazil) | Doxepina/Creatinina: |
ru-RU | Russian (Russian Federation) | Доксепин/Креатинин: Synonyms: Количественный Масс отношение Точка во времени; |
tr-TR | Turkish (Turkey) | Dokzepin/Kreatinin: |
zh-CN | Chinese (China) | 多虑平/肌酐: Synonyms: CR; |
Example Units
Unit | Source |
---|---|
ug/g{creat} | Example UCUM Units |
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