Version 2.73

62621-8PhenX - respiratory - immunoglobulin E - total and specific protocol 090701Trial

Status Information


Term Description

Blood collection and bioassay for ascertaining levels of Immunoglobulin E. Licensing and guideline requirements for manufacturers and laboratories performing these tests have been set forth by the Food and Drug Administration and the Clinical Laboratory Improvement Amendment of 1988. These measures have assisted in ensuring more consistent results but do not address either accuracy or precision parameters in a comprehensive fashion. In summary, one of the major challenges in the development of consistent allergy testing is the need to identify and accept a well-recognized test standard. An ideal immunoassay for specific IgE antibodies should meet certain analytic performance criteria. These criteria include a slope of unity over the useful measurement range for all allergens, low variation across replicate measurements, statistically determined limits of detection, a practical cut-off point, and defined saturation points. For an assay to be considered as a standard, it would require close approximation to these criteria. There is currently no established standard in this field.
Source: Regenstrief LOINC

Fully-Specified Name

PhenX - respiratory - immunoglobulin E - total and specific protocol 090701

Additional Names

Short Name
Resp immunoglobulin E proto

Survey Question


Basic Attributes

First Released
Version 2.36
Last Updated
Version 2.66
Change Reason
Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.

Reference Information

Type Source Reference
Article Consensus measures for Phenotypes and Exposures Williams, P. B., Barnes, J. H., Szeinbach, S. L., & Sullivan, T. J. (2000). Analytic precision and accuracy of commercial immunoassays for specific IgE: establishing a standard. Journal of Allergy and Clinical Immunology, 105(6), 1221-1230.
Article Consensus measures for Phenotypes and Exposures Dolen, WK. (2003). IgE antibody in the serum--detection and diagnostic significance. Allergy, 58(5), 717-723.

Member of these Panels

LOINC Long Common Name
62611-9 PhenX domain - Respiratory

Language Variants Get Info

zh-CNChinese (China)
PhenX - 呼吸系统 - 免疫球蛋白 E - 总计与特异性方案 090701:-:时间点:^患者:-:PhenX
it-ITItalian (Italy)
PhenX - respiratorio - Immunoglobuline E - totali e specifiche, protocollo:-:Pt:^Paziente:-:PhenX
ru-RURussian (Russian Federation)
PhenX - дыхание - иммуноглобулин Е - общий и специфический протокол:-:ТчкВрм:^Пациент:-:PhenX
es-MXSpanish (Mexico)
PhenX - respiratorio - inmunoglobulina E - protocolo total y específico 090701:-:Punto temporal:^ Paciente:-:PhenX

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