LOINC
Version 2.69

62641-6PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701Trial

Status Information

Status
Trial

Term Description

A biospecimen is collected from the respondent to measure cotinine, a marker of either smoking or of environmental tobacco smoke exposure. One of the most common methods is via a urine sample obtained from the respondent. Cotinine in urine is measured by gas chromatography mass spectrometry (GC-MS). Other biological matrices (blood, hair, saliva) may be used to measure cotinine. Information about collection and analysis of those matrices is found in the Supplemental Information: Blood, Hair, and Saliva Assays for Tobacco Smoke Exposure. Caffeine may interfere with the accuracy of the results. During the gas chromatography analysis, this interference can be minimized by ramping up the temperature and eluting the caffeine later than the cotinine.
Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
62641-6 PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Indent10366-3 Cotinine [Mass/volume] in Urine O ng/mL

Fully-Specified Name

Component
PhenX - respiratory - urine assay for tobacco smoke exposure protocol 091701
Property
-
Time
Pt
System
^Patient
Scale
-
Method
PhenX

Additional Names

Short Name
Resp urine assay smoke exp proto

Survey Question

Source
PX091701

Basic Attributes

Class
PANEL.PHENX
Type
Clinical
First Released
Version 2.36
Last Updated
Version 2.66
Change Reason
Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type
Panel

Reference Information

Type Source Reference
Article Consensus measures for Phenotypes and Exposures Man, C. N., L.-H. Gam, Ismail, S., Lajis, R., Awang, R. 2006. Simple, rapid and sensitive assay method for simultaneous quantification of urinary nicotine and cotinine using gas chromatography-mass spectrometry. J of Chromatography B 844(2): 322-327.
Article Consensus measures for Phenotypes and Exposures Bernowitz, N.L. (1999). Biomarkers of Environmental Tobacco Smoke Exposure. Environ Health Perspect. 107(Suppl 2):3 49-355.
Article Consensus measures for Phenotypes and Exposures Kuo, H.W., Yang, J.S., Chiu, M.C. (2002). Determination of urinary and salivary cotinine using gas and liquid chromatography and enzyme-linked immunosorbent assay. J Chromatogr B Analyt Technol Biomed Life Sci. 768(2):297-303.
Article Consensus measures for Phenotypes and Exposures Dhar, Preeti. (2004). Measuring tobacco smoke exposure: quantifying nicotine/cotinine concentration in biological samples by colorimetry, chromatography and immunoassay methods. J Pharm Biomed Anal, 35(2004), 155-168.
Article Consensus measures for Phenotypes and Exposures Benowitz, Neal L. (1996). Cotinine as a biomarker of environmental tobacco smoke exposure. Epidemiol Rev, 18(2), 188-204.

Member of these Panels

LOINC Long Common Name
62611-9 PhenX domain - Respiratory

Language Variants Get Info

zh-CNChinese (China)
PhenX - 呼吸系统 - 烟草烟雾暴露尿液检测方案 091701:-:时间点:^患者:-:PhenX
it-ITItalian (Italy)
PhenX - respiratorio - esame delle urine per l'esposizione al fumo di tabacco, protocollo:-:Pt:^Paziente:-:PhenX
ru-RURussian (Russian Federation)
PhenX - дыхание - мочи анализ для подтверждения табакокурения протокол:-:ТчкВрм:^Пациент:-:PhenX

LOINC FHIR® API Example - CodeSystem Request Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62641-6