62803-2

PhenX - fasting C-peptide assay for residual beta cell function protocol 141201

Active

Term Description

This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for C-peptide, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable stand alone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the C-peptide Assay can be performed on individuals who have not met the fasting requirements.

Reference Information

Type	Source	Reference
Article	Consensus measures for Phenotypes and Exposures	American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.
Citation	Consensus measures for Phenotypes and Exposures	Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Laboratory Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2007.
Article	Consensus measures for Phenotypes and Exposures	Marques, RG, Fontaine, MJ, & Rogers, J. (2004). C-peptide - much more than a byproduct of insulin biosynthesis. Pancreas, 29(3), 231-238.

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC	Name	Example UCUM Units
62803-2	PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
Indent66164-5	Did you eat or drink anything other than plain water after 11:30 last night?
Indent66165-2	When did you last eat or drink anything other than plain water?
Indent66166-0	Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Indent66167-8	If Yes, record date
Indent66168-6	Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Indent66169-4	If Yes, record date
Indent66170-2	Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Indent66171-0	If Yes, record date
Indent66172-8	Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Indent66173-6	If Yes, record date
Indent66182-7	Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Indent66183-5	If Yes, record date
Indent66177-7	Do you have hemophilia?
Indent66178-5	Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66179-3	Exclusion Criteria
Indent66180-1	Was blood drawn?
Indent66181-9	Was full sample obtained?
Indent8251-1	Service comment
Indent8251-1	Service comment
Indent66200-7	Repeatability of the assay	{ratio}
Indent66201-5	Coefficient of variation for the assay	{CV}
Indent66202-3	Was the participant fasting?

LOINC Names Get Info

Fully-Specified Name: PhenX - fasting C-peptide assay for residual beta cell function protocol 141201:-:Pt:^Patient:-:PhenX
Long Common Name: PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
Short Name: Fasting C-peptide proto

Part Model Get Info

Component
PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
LP112340-7
- Analyte
  PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
  LP112340-7
  - Component Numerator
    PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
    LP112340-7
    - Component Numerator Core
      PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
      LP112340-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
-
LP6769-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
^Patient
LP310005-6
- System Core
  NULL
- Super System
  Patient
  LP6985-8
Scale
-
LP7747-1
Method
PhenX
LP95333-8

Survey Question

: PX141201

Code System	Code	Code Text	Code Version
PhenX (Consensus measures for Phenotypes and Exposures)	141201	fasting_c_peptide_assay

Basic Attributes

Class: PANEL.PHENX
Type: Clinical
First Released: Version 2.36
Last Updated: Version 2.81 (MIN)
Change Reason: Release 2.81: Status: Changing PhenX Concept from Status = Trial to Active; Previous Releases: Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type: Panel

Member of these Panels

LOINC	Long Common Name
62787-7	PhenX domain - Diabetes

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	PhenX - προσδιορισμός C-πεπτιδίου νηστείας για υπολειμματική λειτουργία β-κυττάρων πρωτόκολλο 141201:-:Pt:^Ασθενής:-:PhenX Synonyms: - C PANEL.PHENX PHENX PhenX - προσδιορισμός C-πεπτιδίου νηστείας για υπολειμματική λειτουργία β-κυττάρων πρωτόκολλο 141201 Pt Ασθενής Λειτουργία Πεπτίδιο C
es-MX	Spanish (Mexico)	PhenX: ensayo de péptido C en ayunas para el protocolo de función residual de células beta 141201:-:Punto temporal:^ Paciente:-:PhenX
it-IT	Italian (Italy)	PhenX - test peptide C a digiuno per la funzione delle cellule beta residue, protocollo:-:Pt:^Paziente:-:PhenX Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio)
ru-RU	Russian (Russian Federation)	PhenX - голодание С-пептид анализ на остаточную бета клеток функцию протокол:-:ТчкВрм:^Пациент:-:PhenX Synonyms: C белок Точка во времени;Момент
zh-CN	Chinese (China)	PhenX - 残余 beta 细胞功能空腹 C-肽检测方案 141201:-:时间点:^患者:-:PhenX Synonyms: B C 型;丙;丙型 Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 FCN PhenX - 残余 beta 细胞功能空腹（禁食、断食、不吃饭） C-肽检测方案 141201;PhenX - 残余（残存） beta 细胞（β细胞）功能空腹 C-肽（C肽）检测方案;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 β 前胰岛素 C 肽;胰岛素原 C 肽医嘱套餐医嘱套餐类医嘱套餐组医嘱组医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组医嘱组合医嘱组合类医嘱组套医嘱组套类医嘱组类医疗服务对象;客户;病人;病患;病号;超系统 - 病人多重;多重型;多重标尺类型;多重精度类型套餐套餐医嘱套餐医嘱组套餐医嘱组类实验室医嘱套餐实验室医嘱套餐类实验室医嘱组实验室医嘱组合类实验室医嘱组套实验室医嘱组套类实验室套餐医嘱组实验室套餐医嘱组类实验室检验项目医嘱组合类实验室检验项目组合类时刻;随机;随意;瞬间检验医嘱组合类检验项目医嘱组合类检验项目组合类组组合组合医嘱组合类组套缩氨酸贝塔

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62803-2
Questionnaire definition: https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62803-2

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.