Version 2.78

Status Information

Status
TRIAL

Term Description

This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for C-peptide, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable stand alone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the C-peptide Assay can be performed on individuals who have not met the fasting requirements.
Source: Regenstrief LOINC

Reference Information

Type Source Reference
Article Consensus measures for Phenotypes and Exposures American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.
Citation Consensus measures for Phenotypes and Exposures Centers for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Laboratory Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2007.
Article Consensus measures for Phenotypes and Exposures Marques, RG, Fontaine, MJ, & Rogers, J. (2004). C-peptide - much more than a byproduct of insulin biosynthesis. Pancreas, 29(3), 231-238.

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
62803-2 PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
Indent66164-5 Did you eat or drink anything other than plain water after 11:30 last night?
Indent66165-2 When did you last eat or drink anything other than plain water?
Indent66166-0 Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Indent66167-8 If Yes, record date
Indent66168-6 Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Indent66169-4 If Yes, record date
Indent66170-2 Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Indent66171-0 If Yes, record date
Indent66172-8 Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Indent66173-6 If Yes, record date
Indent66182-7 Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Indent66183-5 If Yes, record date
Indent66177-7 Do you have hemophilia?
Indent66178-5 Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66179-3 Exclusion Criteria
Indent66180-1 Was blood drawn?
Indent66181-9 Was full sample obtained?
Indent8251-1 Service comment
Indent8251-1 Service comment
Indent66200-7 Repeatability of the assay {ratio}
Indent66201-5 Coefficient of variation for the assay {CV}
Indent66202-3 Was the participant fasting?

Fully-Specified Name

Component
PhenX - fasting C-peptide assay for residual beta cell function protocol 141201
Property
-
Time
Pt
System
^Patient
Scale
-
Method
PhenX

Additional Names

Short Name
Fasting C-peptide proto

Survey Question

Source
PX141201

Basic Attributes

Class
PANEL.PHENX
Type
Clinical
First Released
Version 2.36
Last Updated
Version 2.66
Change Reason
Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type
Panel

Member of these Panels

LOINC Long Common Name
62787-7 PhenX domain - Diabetes

Language Variants Get Info

Tag Language Translation
es-MX Spanish (Mexico) PhenX: ensayo de péptido C en ayunas para el protocolo de función residual de células beta 141201:-:Punto temporal:^ Paciente:-:PhenX
it-IT Italian (Italy) PhenX - test peptide C a digiuno per la funzione delle cellule beta residue, protocollo:-:Pt:^Paziente:-:PhenX
Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio)
ru-RU Russian (Russian Federation) PhenX - голодание С-пептид анализ на остаточную бета клеток функцию протокол:-:ТчкВрм:^Пациент:-:PhenX
Synonyms: C белок Точка во времени;Момент
zh-CN Chinese (China) PhenX - 残余 beta 细胞功能空腹 C-肽检测方案 141201:-:时间点:^患者:-:PhenX
Synonyms: B C 型;丙;丙型 Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 FCN PhenX - 残余 beta 细胞功能空腹（禁食、断食、不吃饭） C-肽检测方案 141201;PhenX - 残余（残存） beta 细胞（β细胞）功能空腹 C-肽（C肽）检测方案;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 β 前胰岛素 C 肽;胰岛素原 C 肽 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套 缩氨酸 贝塔

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62803-2
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62803-2