62805-7
PhenX - fasting serum insulin protocol 141301
Trial
Status Information
- Status
- TRIAL
Term Description
This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for insulin, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable standalone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the Serum Insulin Assay can be performed on individuals who have not met the fasting requirements. The Diabetes Working Group notes that there are also protocols to collect samples for Serum Insulin concentrations at 0, 30, 60, 90 and 120 minutes and that this could be done at the same time as the Oral Glucose Tolerance Test. Such protocols would give extra specificity and information but would increase the burden on both the participant and investigator.
Source: Regenstrief LOINC
Reference Information
| Type | Source | Reference |
|---|---|---|
| Article | Consensus measures for Phenotypes and Exposures | American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61. |
| Article | Consensus measures for Phenotypes and Exposures | Marques, RG, Fontaine, MJ, & Rogers, J. (2004). C-peptide - much more than a byproduct of insulin biosynthesis. Pancreas, 29(3), 231-238. |
Panel Hierarchy
Details for each LOINC in Panel LHC-Forms
| LOINC | Name | R/O/C | Cardinality | Example UCUM Units |
|---|---|---|---|---|
| 62805-7 | PhenX - fasting serum insulin protocol 141301 | |||
| Indent66164-5 | Did you eat or drink anything other than plain water after 11:30 last night? | |||
| Indent66165-2 | When did you last eat or drink anything other than plain water? | |||
| Indent66166-0 | Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.] | |||
| Indent66167-8 | If Yes, record date | |||
| Indent66168-6 | Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor? | |||
| Indent66169-4 | If Yes, record date | |||
| Indent66170-2 | Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies? | |||
| Indent66171-0 | If Yes, record date | |||
| Indent66172-8 | Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals? | |||
| Indent66173-6 | If Yes, record date | |||
| Indent66182-7 | Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.] | |||
| Indent66183-5 | If Yes, record date | |||
| Indent66177-7 | Do you have hemophilia? | |||
| Indent66178-5 | Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks? | |||
| Indent66505-9 | Exclusion Criteria | |||
| Indent66180-1 | Was blood drawn? | |||
| Indent66181-9 | Was full sample obtained? | |||
| Indent8251-1 | Service comment | |||
| Indent8251-1 | Service comment | |||
| Indent66200-7 | Repeatability of the assay | {ratio} | ||
| Indent66201-5 | Coefficient of variation for the assay | {CV} | ||
| Indent66202-3 | Was the participant fasting? |
Fully-Specified Name
- Component
- PhenX - fasting serum insulin protocol 141301
- Property
- -
- Time
- Pt
- System
- ^Patient
- Scale
- -
- Method
- PhenX
Additional Names
- Short Name
- Fasting serum insulin proto
Survey Question
- Source
- PX141301
Basic Attributes
- Class
- PANEL.PHENX
- Type
- Clinical
- First Released
- Version 2.36
- Last Updated
- Version 2.66
- Change Reason
- Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
- Panel Type
- Panel
Member of these Panels
| LOINC | Long Common Name |
|---|---|
| 62787-7 | PhenX domain - Diabetes |
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-MX | Spanish (Mexico) | PhenX - protocolo de insulina sérica en ayunas 141301: |
| it-IT | Italian (Italy) | PhenX - insulina nel siero a digiuno, protocollo: Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio) |
| ru-RU | Russian (Russian Federation) | PhenX - голодание сывороточный инсулин протокол: Synonyms: PhenX - натощак сывороточный инсулин протокол Точка во времени; |
| zh-CN | Chinese (China) | PhenX - 空腹血清胰岛素方案 141301: Synonyms: "sliding scale" 胰岛素剂量调整法; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=62805-7 - Questionnaire definition
- https:
//fhir.loinc.org/Questionnaire/?url=http: //loinc.org/q/62805-7
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright