62805-7

PhenX - fasting serum insulin protocol 141301

Active

Term Description

This protocol provides instructions for drawing, processing and storing blood according to the National Health and Nutrition Examination Survey (NHANES) methods. As there are no standard assays for insulin, the protocol also provides basic guidelines to aid comparability among different studies. Although all three are valuable standalone measures and all should be collected if resources are available, the Diabetes Working Group recommends that investigators prioritize Insulin 1st, C-peptide 2nd and Proinsulin 3rd. This is because results from the Insulin bioassay can be combined with results from Fasting Plasma Glucose bioassay to derive the homeostatic model assessment (HOMA) of insulin resistance and pancreatic beta cell function. The Diabetes Working Group notes that while it is not the preferred method, the Serum Insulin Assay can be performed on individuals who have not met the fasting requirements. The Diabetes Working Group notes that there are also protocols to collect samples for Serum Insulin concentrations at 0, 30, 60, 90 and 120 minutes and that this could be done at the same time as the Oral Glucose Tolerance Test. Such protocols would give extra specificity and information but would increase the burden on both the participant and investigator.

Reference Information

Type	Source	Reference
Article	Consensus measures for Phenotypes and Exposures	American Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.
Article	Consensus measures for Phenotypes and Exposures	Marques, RG, Fontaine, MJ, & Rogers, J. (2004). C-peptide - much more than a byproduct of insulin biosynthesis. Pancreas, 29(3), 231-238.

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINC	Name	Example UCUM Units
62805-7	PhenX - fasting serum insulin protocol 141301
Indent66164-5	Did you eat or drink anything other than plain water after 11:30 last night?
Indent66165-2	When did you last eat or drink anything other than plain water?
Indent66166-0	Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Indent66167-8	If Yes, record date
Indent66168-6	Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Indent66169-4	If Yes, record date
Indent66170-2	Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Indent66171-0	If Yes, record date
Indent66172-8	Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Indent66173-6	If Yes, record date
Indent66182-7	Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Indent66183-5	If Yes, record date
Indent66177-7	Do you have hemophilia?
Indent66178-5	Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66505-9	Exclusion Criteria
Indent66180-1	Was blood drawn?
Indent66181-9	Was full sample obtained?
Indent8251-1	Service comment
Indent8251-1	Service comment
Indent66200-7	Repeatability of the assay	{ratio}
Indent66201-5	Coefficient of variation for the assay	{CV}
Indent66202-3	Was the participant fasting?

LOINC Names Get Info

Fully-Specified Name: PhenX - fasting serum insulin protocol 141301:-:Pt:^Patient:-:PhenX
Long Common Name: PhenX - fasting serum insulin protocol 141301
Short Name: Fasting serum insulin proto

Part Model Get Info

Component
PhenX - fasting serum insulin protocol 141301
LP112368-8
- Analyte
  PhenX - fasting serum insulin protocol 141301
  LP112368-8
  - Component Numerator
    PhenX - fasting serum insulin protocol 141301
    LP112368-8
    - Component Numerator Core
      PhenX - fasting serum insulin protocol 141301
      LP112368-8
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
-
LP6769-6
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
^Patient
LP310005-6
- System Core
  NULL
- Super System
  Patient
  LP6985-8
Scale
-
LP7747-1
Method
PhenX
LP95333-8

Survey Question

: PX141301

Code System	Code	Code Text	Code Version
PhenX (Consensus measures for Phenotypes and Exposures)	141301	fasting_serum_insulin

Basic Attributes

Class: PANEL.PHENX
Type: Clinical
First Released: Version 2.36
Last Updated: Version 2.81 (MIN)
Change Reason: Release 2.81: Status: Changing PhenX Concept from Status = Trial to Active; Previous Releases: Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type: Panel

Member of these Panels

LOINC	Long Common Name
62787-7	PhenX domain - Diabetes

Language Variants Get Info

Tag	Language	Translation
el-GR	Greek (Greece)	PhenX - ινσουλίνη ορού νηστείας πρωτόκολλο 141301:-:Pt:^Ασθενής:-:PhenX Synonyms: - PANEL.PHENX PHENX PhenX - ινσουλίνη ορού νηστείας πρωτόκολλο 141301 Pt Ασθενής Ινσουλίνη
es-MX	Spanish (Mexico)	PhenX - protocolo de insulina sérica en ayunas 141301:-:Punto temporal:^ Paciente:-:PhenX
it-IT	Italian (Italy)	PhenX - insulina nel siero a digiuno, protocollo:-:Pt:^Paziente:-:PhenX Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio)
ru-RU	Russian (Russian Federation)	PhenX - голодание сывороточный инсулин протокол:-:ТчкВрм:^Пациент:-:PhenX Synonyms: PhenX - натощак сывороточный инсулин протокол Точка во времени;Момент
zh-CN	Chinese (China)	PhenX - 空腹血清胰岛素方案 141301:-:时间点:^患者:-:PhenX Synonyms: "sliding scale" 胰岛素剂量调整法;HUM;Humulin;IH7;Insul;Lente;NPH;Semilente;Sliding;Ultralente;中性鱼精蛋白胰岛素（NPH 胰岛素）;人胰岛素;优泌林;优泌林（Humulin，人工胰岛素，人胰岛素，重组人胰岛素）;半慢胰岛素;半慢胰岛素（Semilente）;慢效胰岛素;慢效胰岛素（Lente）;慢胰岛素;特慢胰岛素;特慢胰岛素（Ultralente）;胰岛素制剂;蛇麻素（Humulin）;超慢胰岛素;长效胰岛素 Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 PhenX - 空腹（禁食、断食、不吃饭）血清胰岛素方案 141301;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Ser SR 医嘱套餐医嘱套餐类医嘱套餐组医嘱组医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组医嘱组合医嘱组合类医嘱组套医嘱组套类医嘱组类医疗服务对象;客户;病人;病患;病号;超系统 - 病人多重;多重型;多重标尺类型;多重精度类型套餐套餐医嘱套餐医嘱组套餐医嘱组类实验室医嘱套餐实验室医嘱套餐类实验室医嘱组实验室医嘱组合类实验室医嘱组套实验室医嘱组套类实验室套餐医嘱组实验室套餐医嘱组类实验室检验项目医嘱组合类实验室检验项目组合类时刻;随机;随意;瞬间检验医嘱组合类检验项目医嘱组合类检验项目组合类浆液组组合组合医嘱组合类组套血清（Serum，Ser，SR）

LOINC Terminology Service (API) using HL7^® FHIR^® Get Info

CodeSystem lookup: https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62805-7
Questionnaire definition: https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62805-7

LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.