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Term Description

Participants are asked to fast for at least 9 hours (generally overnight) prior to the Oral Glucose Tolerance test. Participants are asked a series of exclusionary questions and then have an initial blood draw to determine Fasting Plasma Glucose levels. Participants are next asked to drink a calibrated dose (generally 75 grams / 10 ounces) of a dextrose solution (e.g., Trutol®) and have a second venipuncture 2 hours (plus or minus 15 minutes) after the first venipuncture. The plasma is separated from the blood via centrifugation and glucose concentration is determined via the hexokinase method. The Oral Glucose Tolerance Test includes a Fasting Plasma Glucose assay as the first step. Therefore performing the Oral Glucose Tolerance Test and the Fasting Plasma Glucose Assay for Diabetes Screening together will result collecting in the Fasting Plasma Glucose Assay twice. The Diabetes Working Group notes that an alternative to the single two-hour post load value is to establish a catheter and obtain samples for Serum Glucose concentrations at 0, 30, 60, 90 and 120 minutes. There are also protocols for more rapid sampling of Serum Glucose concentrations. In addition, the Diabetes Working Group notes that there are also protocols to collect samples for Serum Insulin concentrations at 0, 30, 60, 90 and 120 minutes and that this could be done at the same time as the Oral Glucose Tolerance Test. Such protocols would give extra specificity and information but would increase the burden on both the participant and investigator.

Reference Information

TypeSourceReference
ArticleConsensus measures for Phenotypes and ExposuresAmerican Diabetes Association. (2009). Diagnosis and classification of diabetes mellitus. Diabetes Care, 32(Supplement 1), S62 - S67.
ArticleConsensus measures for Phenotypes and ExposuresAmerican Diabetes Association. (2010). Diagnosis and classification of diabetes mellitus. Diabetes Care, 33 (Supplement 1), S11 - S61.
CitationConsensus measures for Phenotypes and ExposuresCenters for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Oral Glucose Tolerance Test (OGTT) Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2005-2006
CitationConsensus measures for Phenotypes and ExposuresCenters for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Laboratory Procedures Manual. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2007-2008
CitationConsensus measures for Phenotypes and ExposuresCenters for Disease Control and Prevention (CDC). National Center for Health Statistics (NCHS). National Health and Nutrition Examination Survey Questionnaire. Shared Exclusion Questions for the MEC Examination. Hyattsville, MD: U.S. Department of Health and Human Services, Centers for Disease Control and Prevention, 2002. (questions 6 and 7)
CitationConsensus measures for Phenotypes and ExposuresAmerican Diabetes Association. (2008). Standards of medical care in diabetes - 2008. Diabetes Care, 31(Supplement 1), S12 - S54

Panel Hierarchy

Details for each LOINC in Panel LHC-Forms

LOINCNameR/O/CCardinalityExample UCUM Units
62856-0PhenX - oral glucose tolerance test protocol 141001
Indent66164-5Did you eat or drink anything other than plain water after 11:30 last night?
Indent66165-2When did you last eat or drink anything other than plain water?
Indent66166-0Have you had any of the following since {insert time from 1 here}? Coffee or tea with cream and sugar? [Include milk or non-dairy creamers.]
Indent66167-8If Yes, record date
Indent66168-6Have you had any of the following since {insert time from 1 here}? Alcohol, such as beer, wine, or liquor?
Indent66169-4If Yes, record date
Indent66170-2Have you had any of the following since {insert time from 1 here}? Gum, breath mints, lozenges, or cough drops, or other cough or cold remedies?
Indent66171-0If Yes, record date
Indent66172-8Have you had any of the following since {insert time from 1 here}? Antacids, laxatives, or anti-diarrheals?
Indent66173-6If Yes, record date
Indent66182-7Have you had any of the following since {insert time from 1 here}? Dietary Supplements such as vitamins and minerals? [Include multivitamins and single nutrient supplements.]
Indent66183-5If Yes, record date
Indent66174-4Are you currently pregnant?
Indent66175-1{Is SP/Are you} now taking insulin?
Indent66176-9{Is SP/Are you} now taking diabetic pills to lower {his/her}/your} blood sugar?
Indent66177-7Do you have hemophilia?
Indent66178-5Have you received cancer chemotherapy in the past four weeks or do you anticipate such therapy in the next four weeks?
Indent66504-2Exclusion Criteria
Indent8251-1Service comment
Indent8251-1Service comment
Indent29463-7Body weightO[lb_av];kg
Indent66203-1Record the amount of dextrose solution administeredmL
Indent66204-9Record the amount of dextrose solution the participant drank
Indent66205-6Record whether all of the solution was consumed in 10 minutes
Indent66206-4Record the number of minutes elapsed between consuming dextrose solution and administering the second blood drawmin
Indent66208-0Make of the equipment used to perform...
Indent74719-6Manufacturer of the equipment used
Indent66240-3Blood draw [PhenX]

LOINC Names Get Info

Fully-Specified Name
PhenX - oral glucose tolerance test protocol 141001:-:Pt:^Patient:-:PhenX
Long Common Name
PhenX - oral glucose tolerance test protocol 141001
Short Name
Oral glucose tolerance test proto

Part Model Get Info

  • Component
    PhenX - oral glucose tolerance test protocol 141001
    LP112419-9
    • Analyte
      PhenX - oral glucose tolerance test protocol 141001
      LP112419-9
      • Component Numerator
        PhenX - oral glucose tolerance test protocol 141001
        LP112419-9
        • Component Numerator Core
          PhenX - oral glucose tolerance test protocol 141001
          LP112419-9
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    -
    LP6769-6
  • Time
    Pt
    LP6960-1
  • System
    ^Patient
    LP310005-6
    • System Core
      NULL
       
    • Super System
      Patient
      LP6985-8
  • Scale
    -
    LP7747-1
  • Method
    PhenX
    LP95333-8

Survey Question

PX141001

Basic Attributes

Class
PANEL.PHENX
Type
Clinical
First Released
Version 2.36
Last Updated
Version 2.81 (MIN)
Change Reason
Release 2.81: Status: Changing PhenX Concept from Status = Trial to Active; Previous Releases: Updated the PhenX ID from "PhenX.<ID>" to "PX<ID>" in Survey Question Source field to align with the variable identifier used in the PhenX Toolkit.; Added the PhenX protocol ID to the Component to clearly define the protocol version for which this panel is based upon.
Panel Type
Panel

Member of these Panels

LOINCLong Common Name
62787-7PhenX domain - Diabetes

Language Variants Get Info

TagLanguageTranslation
el-GRGreek (Greece)PhenX - δοκιμασία ανοχής γλυκόζης από το στόμα πρωτόκολλο 141001:-:Pt:^Ασθενής:-:PhenX
Synonyms: - PANEL.PHENX PHENX PhenX - δοκιμασία ανοχής γλυκόζης από το στόμα πρωτόκολλο 141001 Pt Ανοχή γλυκόζης Ασθενής Γλυκόζη
es-MXSpanish (Mexico)PhenX - protocolo de prueba de tolerancia a la glucosa oral 141001:-:Punto temporal:^ Paciente:-:PhenX
it-ITItalian (Italy)PhenX - test di tolleranza al carico orale di glucosio, protocollo:-:Pt:^Paziente:-:PhenX
Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio) Tolleranza al glucosio
ru-RURussian (Russian Federation)PhenX - оральный к глюкозе толерантности тест протокол:-:ТчкВрм:^Пациент:-:PhenX
Synonyms: Толерантность к глюкозе Точка во времени;Момент
zh-CNChinese (China)PhenX - 口服葡萄糖耐量试验方案 141001:-:时间点:^患者:-:PhenX
Synonyms: Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Consensus measures for Phenotypes and eXposures;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 Glu tol;GTT;糖耐量;葡萄糖耐受;葡萄糖耐受力;葡萄糖耐受能力 Glu;Gluc;右旋糖;葡糖 PhenX - 口服糖耐量试验方案 141001;Consensus measures for Phenotypes and eXposures;PhenX;暴露;接触;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标 医嘱套餐 医嘱套餐类 医嘱套餐组 医嘱组 医嘱组.PhenX;组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）.PhenX;Consensus measures for Phenotypes and eXposures;PhenX;表型与暴露共识指标;表现型与暴露共识指标;表型与暴露公认指标;PhenX 医嘱组 医嘱组合 医嘱组合类 医嘱组套 医嘱组套类 医嘱组类 医疗服务对象;客户;病人;病患;病号;超系统 - 病人 多重;多重型;多重标尺类型;多重精度类型 套餐 套餐医嘱 套餐医嘱组 套餐医嘱组类 实验室医嘱套餐 实验室医嘱套餐类 实验室医嘱组 实验室医嘱组合类 实验室医嘱组套 实验室医嘱组套类 实验室套餐医嘱组 实验室套餐医嘱组类 实验室检验项目医嘱组合类 实验室检验项目组合类 时刻;随机;随意;瞬间 检验医嘱组合类 检验项目医嘱组合类 检验项目组合类 组 组合 组合医嘱 组合类 组套

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=62856-0
Questionnaire definition
https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/62856-0