62874-3
Deprecated PhenX measure - assay for human leukocyte antigen (HLA) genotyping
Deprecated
Status Information
- Status
- DEPRECATED
- Comment
- Measure terms were added to match PhenX hierarchy but make it difficult to locate protocols (which contain the set of variables you would use for a particular purpose). They have been deprecated and mapped directly to protocols.
Term Description
A bioassay to obtain the specific allelic genotypes of several of the human leukocyte antigens, whose genes reside on chromosome 6p within the Major Histocompatibility Region (MHC). The measure determines the alleles/single nucleotide polymorphisms that are present in the human leukocyte antigen regions of chromosome 6 to assess the major histocompatability system. The genetic variation within the human leukocyte antigen region determines the person's immune response and has been tied to specific autoimmune disorders such as Graves' disease and Hashimoto's thyroiditis, as well as other diseases such as multiple sclerosis, ankylosing spondylitis, and type 1 diabetes. This assay is similar to the genotyping performed in genome wide association studies but captures much more of the genetic variation within the human leukocyte antigen region than would be covered with "tag" single nucleotide polymorphisms.
Part Description
LP20670-3 Leukocyte
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010)
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- PhenX measure - assay for human leukocyte antigen (HLA) genotyping:
-: Pt: ^Patient: -: PhenX - Long Common Name
- Deprecated PhenX measure - assay for human leukocyte antigen (HLA) genotyping
Part Model Get Info
- Component
- PhenX measure - assay for human leukocyte antigen (HLA) genotyping
LP112431-4
- Analyte
- PhenX measure - assay for human leukocyte antigen (HLA) genotyping
LP112431-4
- Component Numerator
- PhenX measure - assay for human leukocyte antigen (HLA) genotyping
LP112431-4
- Component Numerator Core
- PhenX measure - assay for human leukocyte antigen (HLA) genotyping
LP112431-4
- Component Numerator Core Suffix
- NULL
- Component Denominator
- NULL
- Component Denominator Core
- NULL
- Component Denominator Core Suffix
- NULL
- Challenge
- NULL
- Adjustment
- NULL
- Count
- NULL
- Property
- -
LP6769-6
- Time
- Pt
LP6960-1
- Time Core
- Pt
LP6960-1
- Time Modifier
- NULL
- System
- ^Patient
LP310005-6
- System Core
- NULL
- Super System
- Patient
LP6985-8
- Scale
- -
LP7747-1
- Method
- PhenX
LP95333-8
Survey Question
- PhenX.160600
Basic Attributes
- Class
- PANEL.PHENX
- Type
- Clinical
- First Released
- Version 2.36
- Last Updated
- Version 2.46 (DEL)
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| el-GR | Greek (Greece) | Μέτρηση PhenX - προσδιορισμός για γονοτύπηση για ανθρώπινα λευκοκυτταρικά αντιγόνα (HLA): Synonyms: - PANEL.PHENX PHENX Pt Ανθρώπινα λευκοκυτταρικά αντιγόνα Ασθενής Μέτρηση PhenX - προσδιορισμός για γονοτύπηση για ανθρώπινα λευκοκυτταρικά αντιγόνα (HLA) |
| es-MX | Spanish (Mexico) | Medida PhenX: |
| it-IT | Italian (Italy) | PhenX, misura - esame per antigene leucocitario umano ( HLA ) genotipizzazione: Synonyms: Panel PhenX paziente PhenX Punto nel tempo (episodio) |
| zh-CN | Chinese (China) | PhenX 指标 - 人类白细胞抗原基因分型: Synonyms: Ag Consensus measures for Phenotypes and eXposures; |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://