Version 2.77

Part Descriptions

LP308657-8   TOP2A gene copy number/Chromosome 17 copy number
Ratio of average counts (per nuclei)of the respective genes. Averages above 2 => amplification of TOP2A; averages <0.8 imply deletions of TOP2A Source: Regenstrief Help

LP62864-1   FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

Fully-Specified Name

Component
TOP2A gene copy number/Chromosome 17 copy number
Property
NRto
Time
Pt
System
Tiss
Scale
Qn
Method
FISH

Additional Names

Short Name
TOP2A copy num/Chr 17 copy num Tiss FISH
Display Name
TOP2A gene copy num/Chromosome 17 copy number FISH (Tiss) [# ratio]
Consumer Name Alpha Get Info
TOP2A gene copy number/Chromosome 17 copy number, Tissue

Basic Attributes

Class
MOLPATH
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.66
Change Reason
Updated Component from "TOP2A/CEP17" and Property from "Ratio" to align with current nomenclature and similar terms
Order vs. Observation
Observation

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Número de copias del gen TOP2A/CEP17:Relación de número:Punto temporal:Tejido:Qn:Hibridación in situ fluoresente (FISH)
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Número de copia del gen TOP2A / número de copia del cromosoma 17:Proporción numérica:Punto temporal:Tejido y frotis:Cuantitativo:Hibridación fluorescente in situ (FISH)
fr-FR French (France) TOP2A gène/chromosome 17 nombre de copie:Nombre/Nombre:Ponctuel:Tissu:Numérique:FISH
it-IT Italian (Italy) TOP2A, numero copia gene/CEP17:NRto:Pt:Tessuto:Qn:FISH
Synonyms: Gene TOP2A Ibridazione in situ fluorescente (FISH) Numero copia gene TOP2A Patologia molecolare Punto nel tempo (episodio) Rapporto numerico Tessuto & Strisci
nl-NL Dutch (Netherlands) aantal kopieën van TOP2A-gen/aantal centromeren van chromosoom 17:aantalsverhouding:moment:weefsel en uitstrijkjes:kwantitatief:FISH
Synonyms: CEP17 TOP2A TOP2A gen
zh-CN Chinese (China) TOP2A 基因拷贝数/染色体 17 拷贝数:计数型比率:时间点:组织与涂片:定量型:FISH
Synonyms: Fluorescent in situ hybridization;荧光原位杂交 TOP2;TP2A;DNA gyrase;DNA topoisomerase (ATP-hydrolyzing);DNA topoisomerase 2-alpha;DNA topoisomerase II, 170 kD;DNA topoisomerase II, alpha isozyme;DNA 促旋酶;DNA 旋转酶;DNA 拓扑异构酶 (ATP-水解);DNA 拓扑异构酶 2-alpha;DNA 拓扑异构酶 II, 170 kD;DNA 拓扑异构酶 II, alpha 同工酶 TOP2A 基因拷贝（副本）数（数量、计数） 个数;数目 分子病理学;分子病理学试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 同一样本内两种不同实体的数量之比;数量型比;数量型比值;数量型比率;数量或计数型比;数量或计数型比值;计数型比;计数型比值;数量或计数型比率 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 染色体 17 （17号染色体）拷贝（副本）数（数量、计数）;17号染色体拷贝（副本）数（数量、计数）;CEP17;CEP17 信号 染色体 17 （17号染色体）拷贝（副本）数（数量、计数）;17号染色体拷贝数;CEP17 染色体二体型+染色体三体型 遗传基因;遗传因子;吉恩;生物基因

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CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63068-1