63070-7

TOP2A gene 17q21-22 deletion and duplication mutation analysis [Presence] in Tissue by FISH

Active

Part Description

LP62864-1 FISH
FISH (fluorescence in situ hybridization) is a cytogenetic technique used to detect and localize the presence or absence of specific DNA sequences on chromosomes. FISH uses fluorescent probes that bind to only those parts of the chromosome with which they show a high degree of sequence similarity. Fluorescence microscopy can be used to find out where the fluorescent probe bound to the chromosomes. FISH is often used for finding specific features in DNA for use in genetic counseling, medicine, and species identification. FISH can also be used to detect and localize specific mRNAs within tissue samples. In this context, it can help define the spatial-temporal patterns of gene expression within cells and tissues. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, FISH

LOINC Names Get Info

Fully-Specified Name: TOP2A gene 17q21-22 deletion+duplication:PrThr:Pt:Tiss:Ord:FISH
Long Common Name: TOP2A gene 17q21-22 deletion and duplication mutation analysis [Presence] in Tissue by FISH
Short Name: TOP2A 17q21-22 Del+Dup Tiss Ql FISH
Display Name: TOP2A gene 17q21-22 del and dup mutation analysis FISH Ql (Tiss)
Consumer Name Alpha Get Info: TOP2A gene 17q21-22 deletion/duplication analysis, Tissue

Part Model Get Info

Component
TOP2A gene 17q21-22 deletion+duplication
LP113344-8
- Analyte
  TOP2A gene 17q21-22 deletion+duplication
  LP113344-8
  - Component Numerator
    TOP2A gene 17q21-22 deletion+duplication
    LP113344-8
    - Component Numerator Core
      TOP2A gene 17q21-22
      LP193288-0
    - Component Numerator Core Suffix
      deletion+duplication
      LP136317-7
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Tiss
LP7641-6
- System Core
  Tiss
  LP7641-6
- Super System
  NULL
Scale
Ord
LP7751-3
Method
FISH
LP62864-1

Basic Attributes

Class: MOLPATH
Type: Laboratory
First Released: Version 2.36
Last Updated: Version 2.61 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Gen TOP2A 17q21-22 delece+duplikace:Přítomnost nebo práh:Časový bod:Tkáně a stěry:Ordinální:Fluorescenční in situ hybridizace (FISH)
el-GR	Greek (Greece)	Γονίδιο TOP2A 17q21-22 διαγραφή+διπλασιασμός:PrThr:Pt:Ιστός:Ord:Φθορίζουσα υβριδοποίηση in situ Synonyms: MOLPATH Ord PrThr Pt Γονίδιο Γονίδιο TOP2A Γονίδιο TOP2A 17q21-22 διαγραφή διαγραφή+διπλασιασμός διπλασιασμός Ιστός Φθορίζουσα υβριδοποίηση in situ
es-ES	Spanish (Spain)	Gen TOP2A 17q21-22 Delección+duplicación:PrThr:Punto temporal:Tejido:Ord:Hibridación in situ fluoresente (FISH)
es-MX	Spanish (Mexico)	Deleción + duplicación del gen TOP2A 17q21-22:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Hibridación fluorescente in situ (FISH)
fr-FR	French (France)	TOP2A gène 17q21-22 délétion+duplication:Présence/Seuil:Ponctuel:Tissu:Qualitatif:FISH
it-IT	Italian (Italy)	TOP2A, gene 17q21-22 Delezione+duplicazione:PrThr:Pt:Tessuto:Ord:FISH Synonyms: Amplificazione/delezione di gene TOP2A 17q21-22 delezione e duplicazione Gene TOP2A Gene TOP2A 17q21-22 Ibridazione in situ fluorescente (FISH) Patologia molecolare Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
nl-NL	Dutch (Netherlands)	TOP2A-gen 17q21-22 deletie + duplicatie:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:FISH Synonyms: TOP2A gen TOP2A gen 17q21-22
pl-PL	Polish (Poland)	TOP2A gen 17q21-22 delecja+duplikacja:granica wykrywalności:punkt w czasie:tkanka i rozmazy:uporządkowany:FISH Synonyms: fluorescencyjna hybrydyzacja in situ Gen TOP2A Gen TOP2A zlokalizowany w regionie q21-22 na 17 chromosomie
tr-TR	Turkish (Turkey)	TOP2A geni 17q21-22 delesyon+duplikasyon:MevcEşik:Zmlı:Doku:Srl:FISH Synonyms: çiftleme Mevcut
zh-CN	Chinese (China)	TOP2A 基因 17q21-22 缺失+重复:存在情况或阈值:时间点:组织与涂片:序数型:FISH Synonyms: Fluorescent in situ hybridization;荧光原位杂交 TOP2;TP2A;DNA gyrase;DNA topoisomerase (ATP-hydrolyzing);DNA topoisomerase 2-alpha;DNA topoisomerase II, 170 kD;DNA topoisomerase II, alpha isozyme;DNA 促旋酶;DNA 旋转酶;DNA 拓扑异构酶 (ATP-水解);DNA 拓扑异构酶 2-alpha;DNA 拓扑异构酶 II, 170 kD;DNA 拓扑异构酶 II, alpha 同工酶 TOP2A 基因 17q21-22 基因扩增+基因缺失依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型分子病理学;分子病理学试验基因复制;基因重复;重复基因缺失（基因缺失、缺损、基因缺损、基因删除、删除、基因丢失）+重复（基因重复）;基因缺失+重复存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间未作说明的组织;组织;组织 & 涂片染色体缺失;染色体区带缺失;基因缺失;缺损;基因缺损;基因删除;删除;基因丢失遗传基因;遗传因子;吉恩;生物基因

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.