63250-5
Ganglioside GM2 IgM Ab [Presence] in Serum by Immunoassay
Active
Part Descriptions
LP62853-4 Ganglioside GM2
Gangliosides are present in the cell membrane and are found predominantly in the nervous system. Ganglioside antibodies against different gangliosides have been associated with different conditions. The GM2 ganglioside, also called Tay-Sachs ganglioside, is a minor component of adult nervous tissue, and pathological storage of GM2 in neurons leads to motor neuron disease. Anti-GM2 IgM antibodies have been found in patients with Guillain-Barré syndrome that is associated with CMV infection. Anti-GM2 antibodies have also been associated with an acute inflammatory neuropathy as a potentially paraneoplastic phenomenon. PMID: 23341581
Source: Regenstrief LOINC, PMID: 23341581
LP222219-0 Ganglioside
A ganglioside molecule consists of a glycosphingolipid (ceramide and oligosaccharide) with one or more sialic acid residues linked to the sugar chain. Molecules with one sialic acid residue are called monosialogangliosides (GM), those with two are called disialogangliosides (GD), and those with three are trisialogangliosides (GT). Gangliosides without any sialic acid residues are called asialogangliosides, while those that do not have a ceramide N-acyl group are called lysogangliosides. The number that typically is included at the end of the name indicates the order in which the molecule was discovered. For example, GM2 is a ganglioside with one sialic acid residue that was the second GM to be identified.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- Ganglioside GM2 Ab.IgM
- Property
- PrThr
- Time
- Pt
- System
- Ser
- Scale
- Ord
- Method
- IA
Additional Names
- Short Name
- GM2 Gangl IgM Ser Ql IA
- Display Name
- Ganglioside GM2 IgM IA Ql (S)
- Consumer Name Alpha Get Info
- Ganglioside GM2 IgM antibody, Blood
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.56
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Panels
LOINC | Long Common Name |
---|---|
82455-7 | Ganglioside Ab panel - Serum |
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG23329-2 | Ganglioside GM2 Ab.IgM| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Gangliósido GM2 IgM: |
es-MX | Spanish (Mexico) | Gangliósido GM2 Ab.IgM: |
et-EE | Estonian (Estonia) | Gangliosiid GM2 antikehad.IgM: Synonyms: Immuunglobuliin M Järgarvuline Juhuslik Seerum |
fr-CA | French (Canada) | Ganglioside GM2, IgM: |
fr-FR | French (France) | Ganglioside GM2 anticorps IgM: |
fr-BE | French (Belgium) | Ganglioside GM2 Anticorps. IgM: Synonyms: Anticorps |
it-IT | Italian (Italy) | Ganglioside GM2 Ab.IgM: Synonyms: Anticorpi IgM anticorpo Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | ganglioside GM2 As.IgM: Synonyms: antistof; |
ru-RU | Russian (Russian Federation) | Ганглиозид GM2 Ат.IgM: Synonyms: Антитело Порядковый Сыворотка Точка во времени; |
tr-TR | Turkish (Turkey) | Gangliozid GM2 Ab.IgM: Synonyms: Ak Ak.IgM İmmünölçüm, immünoassay Mevcut |
zh-CN | Chinese (China) | 神经节苷脂 GM2 抗体.IgM: Synonyms: Ab.IgM; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=63250-5
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright