63335-4
SCL-70 extractable nuclear Ab [Presence] in Body fluid by Immunoassay
Active
Part Descriptions
LP16758-2 SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469
Source: Regenstrief LOINC
, PMID: 11229469
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
Fully-Specified Name
- Component
- SCL-70 extractable nuclear Ab
- Property
- PrThr
- Time
- Pt
- System
- Body fld
- Scale
- Ord
- Method
- IA
Additional Names
- Long Common Name
- SCL-70 extractable nuclear Ab [Presence] in Body fluid by Immunoassay
- Short Name
- ENA Scl70 Ab Fld Ql IA
- Display Name
- SCL-70 extractable nuclear Ab IA Ql (Body fld)
- Consumer Name Alpha Get Info
- SCL-70 extractable nuclear antibody, Body fluid
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.56 (MIN)
- Change Reason
- The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
Member of these Groups Get Info
LOINC Group | Group Name |
---|---|
LG26771-2 | SCL-70 extractable nuclear Ab| |
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
el-GR | Greek (Greece) | Εκχυλίσιμα πυρηνικά SCL-70 Αντίσωμα: Synonyms: PrThr Εκχυλίσιμα πυρηνικά Εκχυλίσιμα πυρηνικά SCL-70 Πυρηνικό |
es-ES | Spanish (Spain) | Antígeno nuclear extraíble SCL-70 Anticuerpos: |
es-MX | Spanish (Mexico) | Ab nuclear extraíble SCL-70: |
fr-CA | French (Canada) | SCL-70 nucléaire soluble, Ac: |
fr-FR | French (France) | SCL-70 anticorps: |
fr-BE | French (Belgium) | SCL-70 nucléaire soluble Ac: Synonyms: Anticorps |
it-IT | Italian (Italy) | Nucleare estraibile SCL-70 Ab: Synonyms: anticorpo ENA Immunoassay Liquido corporeo Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
nl-NL | Dutch (Netherlands) | SCL-70 extraheerbare nucleaire As: Synonyms: antistof; |
pl-PL | Polish (Poland) | SCL-70 rozpuszczalny jądrowy Ab: Synonyms: Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy |
ru-RU | Russian (Russian Federation) | SCL-70 экстрагируемый ядерный Ат: Synonyms: Антитело Порядковый Тела жидкость Точка во времени; |
tr-TR | Turkish (Turkey) | SCL-70 özütlenebilir nükleer Ab: Synonyms: Çekirdek İmmünölçüm, immünoassay Mevcut |
zh-CN | Chinese (China) | SCL-70 可提取性核 抗体: Synonyms: Ab; |
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=63335-4
LOINC Copyright
Copyright © 2025 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://