Version 2.77

Part Description

LP16758-2   SCL-70 extractable nuclear
Topoisomerase I (also known as Scl-70) is a nuclear enzyme that plays a role in releasing tension that is introduced in double-stranded DNA during DNA replication by transiently cleaving and rejoining one strand of the DNA duplex. Anti-Scl-70 autoantibodies are a marker of systemic sclerosis as well as other autoimmune diseases, including systemic lupus erythematosus (SLE). In patients with systemic sclerosis, anti-SCL-70 may be associated with more severe disease, and in patients with SLE, anti-SCL-70 suggests an increased risk of pulmonary hypertension and renal involvement. In general, anti-SCL-70 antibody status may help with diagnosis, treatment planning and prognosis in patients with connective tissue disease. PMID: 11229469 Source: Regenstrief LOINC, PMID: 11229469

Fully-Specified Name

Component
SCL-70 extractable nuclear Ab
Property
PrThr
Time
Pt
System
CSF
Scale
Ord
Method
IA

Additional Names

Short Name
ENA Scl70 Ab CSF Ql IA
Display Name
SCL-70 extractable nuclear Ab IA Ql (CSF)
Consumer Name Alpha Get Info
SCL-70 extractable nuclear antibody, Spinal fluid

Basic Attributes

Class
SERO
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG26773-8 SCL-70 extractable nuclear Ab|PrThr|Pt|CSF

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Antígeno nuclear extraíble SCL-70 Anticuerpos:PrThr:Punto temporal:Líquido Cefalorraquideo:Ord:IA
es-MX Spanish (Mexico) Ab nuclear extraíble SCL-70:Presencia o umbral:Punto temporal:Fluído espinal cerebral:Ordinal:Inmunoensayo
fr-CA French (Canada) SCL-70 nucléaire soluble , Ac:Présence-Seuil:Temps ponctuel:LCR:Ordinal:IA
fr-FR French (France) SCL-70 anticorps:Présence/Seuil:Ponctuel:Liquide céphalorachidien:Qualitatif:Immunoanalyse
fr-BE French (Belgium) SCL-70 nucléaire soluble Ac:PrThr:Temps ponctuel:LCR:Ordinal:IA
Synonyms: Anticorps
it-IT Italian (Italy) Nucleare estraibile SCL-70 Ab:PrThr:Pt:LCS:Ord:IA
Synonyms: anticorpo ENA Immunoassay Liquido cerebrospinale Presenza o Soglia Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant
nl-NL Dutch (Netherlands) SCL-70 extraheerbare nucleaire As:aanwezigheid:moment:liquor cerebrospinalis:ordinaal:immunoassay
Synonyms: antistof; antilichaam IA
pl-PL Polish (Poland) SCL-70 rozpuszczalny jądrowy Ab:granica wykrywalności:punkt w czasie:płyn mózgowo-rdzeniowy:półilościowy:metoda immunologiczna
Synonyms: Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała przeciwjądrowe SCL-70 rozpuszczalny jądrowy
ru-RU Russian (Russian Federation) SCL-70 экстрагируемый ядерный Ат:PrThr:ТчкВрм:ЦСЖ:Пор:IA
Synonyms: Антитело Порядковый Точка во времени;Момент Цереброспинальная жидкость
tr-TR Turkish (Turkey) SCL-70 özütlenebilir nükleer Ab:MevcEşik:Zmlı:BOS:Srl:İA
Synonyms: Ak Çekirdek İmmünölçüm, immünoassay Mevcut
zh-CN Chinese (China) SCL-70 可提取性核 抗体:存在情况或阈值:时间点:脑脊液:序数型:免疫测定法
Synonyms: Ab;自身抗体 ANA CSF CSF;脊髓液;Cerebral spinal fluid;脑脊髓液 ENA Ab ENA SCL-70 Ab ENA SCL-70 抗体 ENA SCL-70;SCL-70 可提取性核 Ag;SCL-70 可提取性核抗原;可提取性核抗原 SCL-70;皮硬化症 Ab;皮硬化症抗体;硬皮病 Ab;硬皮病抗体;硬皮症 Ab;硬皮症抗体 ENA 抗体 ENA;可提取性核 Ag;可提取性核抗原;可提取性核抗原(Extractable Nuclear Antigen,ENA);可提取性细胞核;可提取性细胞核 Ag;可提取性细胞核抗原;盐水可提取性核 Ag;盐水可提取性核抗原;盐水可提取性细胞核 Ag;盐水可提取性细胞核抗原 NA SCL-70 可提取性核 Ab SCL-70 可提取性核 Ag Ab SCL-70 可提取性核抗原抗体 依次型;分类顺序型;定性的;序数型(或称等级型);性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可提取性核 Ab 可提取性核 Ag 之 Ab 可提取性核抗原 SCL-70 Ab 可提取性核抗原 SCL-70 抗体 可提取性核抗原之抗体 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况(存在、存在与否、是否存在)或阈值(界值、界限、阀值、临界值) 抗 ENA 抗可提取性核 Ag 抗可提取性核抗原 抗核 Ab 抗核抗体 抗核抗体(Antinuclear antibody,ANA) 时刻;随机;随意;瞬间 核;胞核 皮硬化症 硬皮病 硬皮病(Scleroderma,SCL) 硬皮症 细胞核 Ab 胞核 Ab 胞核抗体 脊液 脊髓液 脑脊液(Cerebral spinal fluid,CSF) 脑脊髓液 血清;血清学;血清学检验项目;血清学检验项目 (非微生物学);血清学检验项目(非微生物学);血清学检验项目类;血清学检验项目类 (非微生物学);血清学类;血清学类检验项目;血清学类检验项目 (非微生物学);血清学类试验;血清学类试验 (非微生物学);血清学试验;血清学试验 (非微生物学);血清学试验(非微生物学);血清学试验类 (非微生物学);血清类

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=63337-0