63393-3
Jo-1 extractable nuclear Ab [Units/volume] in Body fluid by Immunoassay
Active
Part Descriptions
LP16719-4 Jo-1 extractable nuclear
Aminoacyl-tRNA synthetases (ARS) are enzymes that link amino acids to tRNA molecules and therefore play a key role in protein synthesis. Each ARS is specific for a single amino acid. [NCBI Books: NBK22356] Autoantibodies to ARS are a hallmark of connective tissue diseases including anti-synthetase syndrome (ASS) and idiopathic inflammatory myopathies such as polymyositis (PM) and dermatomyositis (DM). ASS, PM and DM have overlapping features, including myositis, arthralgia, skin manifestations and interstitial lung disease. Antibodies to several specific ARS enzymes have been identified, including anti-histidyl (anti-Jo-1), anti-threonyl (anti-PL-7), anti-alanyl (anti-PL-12), anti-glycyl (anti-Ej), anti-isoleucyl (anti-Oj), anti-asparaginyl (anti-Ks), anti-phenylalanyl (anti-Zo), and anti-tyrosyl (anti-Ha). Different antibodies or patterns of antibodies have been associated with specific clinical features. Anti-Jo-1, anti-Ej, and anti-PL-7 antibodies are associated with myositis, including classic DM, clinically amyopathic DM (CADM) and PM. Anti-PL-12 alone is associated with CADM or interstitial lung disease (ILD). Anti-Ej and anti-PL-12 together are associated with CADM. Anti-Ks and anti-Oj are associated with ILD alone. PMID: 23573256 Anti-Ha and anti-Zo antibodies are the most recent autoantibodies to be identified in patients with symptoms of ASS. PMID: 17392287 Identifying the particular anti-ARS antibodies associated with an individual patient's disease may help guide treatment and predict clinical outcomes.
Source: Regenstrief LOINC,
PMID: 23573256
LP7238-1 Body fld
The LOINC "Body fld" System represents body fluids other than serum, plasma, blood, urine, and cerebrospinal fluid. When a LOINC term with the System "Body fld" is used, the specific specimen source or body fluid type should be reported elsewhere with the result. Where more specific terms for pleural, peritoneal, synovial fluid, etc. exist, we encourage you to use the more specific terms. In contrast to "Body fld", the System "Asp" in LOINC represents the fluid withdrawn during an aspiration procedure from an abnormal collection of fluid, such as from an abscess or cyst. "Asp" is used for abnormal fluid collections that are aspirated, while "Body fld" is used for named body fluids, such as synovial fluid or peritoneal fluid, that are not inherently pathologic.
Source: Regenstrief LOINC
LOINC Names Get Info
- Fully-Specified Name
- Jo-1 extractable nuclear Ab:
ACnc: Pt: Body fld: Qn: IA - Long Common Name
- Jo-1 extractable nuclear Ab [Units/volume] in Body fluid by Immunoassay
- Short Name
- ENA Jo1 Ab Fld IA-aCnc
- Display Name
- Jo-1 extractable nuclear Ab IA Qn (Body fld)
- Consumer Name Alpha Get Info
- Jo-1 extractable nuclear antibody, Body fluid
Part Model Get Info
Basic Attributes
- Class
- SERO
- Type
- Laboratory
- First Released
- Version 2.36
- Last Updated
- Version 2.73 (MIN)
- Change Reason
- The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016.
- Order vs. Observation
- Both
- Common Test Rank Get Info
- 19231
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| cs-CZ | Czech (Czechia) | Antinukleární protilátky Jo-1 extrahovatelné: |
| el-GR | Greek (Greece) | εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Αντίσωμα: Synonyms: ACnc IA Pt Qn SERO Αντίσωμα Εκχυλίσιμα πυρηνικά εκχυλίσιμα πυρηνικά αντιγόνα Jo-1 Πυρηνικό Σωματικό υγρό |
| es-ES | Spanish (Spain) | Jo-1 Anticuerpos: Synonyms: Cuantitativo |
| es-MX | Spanish (Mexico) | Ab nuclear extraíble Jo-1: |
| fr-CA | French (Canada) | Jo-1 nucléaire soluble, Ac: |
| fr-FR | French (France) | Jo-1 Ac: |
| fr-BE | French (Belgium) | Jo-1 nucléaire soluble Ac: Synonyms: Anticorps |
| it-IT | Italian (Italy) | Jo-1, nucleare estraibile Ab: Synonyms: anticorpo Concentrazione Arbitraria ENA Immunoassay Jo1 Liquido corporeo Punto nel tempo (episodio) Sierologia (anticorpi e la maggior parte degli ant |
| nl-NL | Dutch (Netherlands) | jo-1 extraheerbaar nucleair As: Synonyms: antistof; |
| pl-PL | Polish (Poland) | Jo-1 rozpuszczalny jądrowy Ab: Synonyms: Jo-1 rozpuszczalny jądrowy Przeciwciała do rozpuszczalnego antygenu jądrowego Przeciwciała do rozpuszczalnego jądrowego antygenu Jo-1 Przeciwciała przeciwjądrowe |
| ru-RU | Russian (Russian Federation) | Jo-1 экстрагируемый ядерный Ат: Synonyms: Антитело Количественный Произвольная концентрация Тела жидкость Точка во времени; |
| tr-TR | Turkish (Turkey) | Jo-1 öztlenebilir çekirdek Ab: Synonyms: Ak Çekirdek İmmünölçüm, immünoassay |
| zh-CN | Chinese (China) | Jo-1 可提取性核 抗体: Synonyms: Ⅰ Ab; |
Example Units
| Unit | Source |
|---|---|
| [arb'U]/mL | Example UCUM Units |
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LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://