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Part Description

LP14920-0   Clostridioides difficile toxin B
Clostridium difficile toxin B is a toxin produced by the bacteria Clostridium difficile. C. difficile produces two major kinds of toxins that are very potent and lethal; an enterotoxin (Toxin A) and a cytotoxin (Toxin B, this protein). Early studies suggested that toxin A (also known as TcdA) is the major toxin protein causing antibiotic-associated diarrhea (AAD); however, within the last decade it has been shown that Toxin B (or TcdB) plays a more important role in disease than anyone had forecasted. Toxin B has been identified as the major virulence factor that causes the opening of tight junctions of intestinal epithelial cells, which enables toxin to increase vascular permeability and induce hemorrhaging. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Clostridium difficile toxin B

Reference Information

TypeSourceReference
ArticleNCBI PubMedManabe YC, Vinetz JM, Moore RD, Merz C, Charache P, Bartlett JG. Clostridium difficile colitis: an efficient clinical approach to diagnosis. Ann Intern Med. 1995 Dec 1;123(11):835-40. Link to PubMed

LOINC Names Get Info

Fully-Specified Name
Clostridioides difficile toxin B:ACnc:Pt:Stool:Qn:IA
Long Common Name
Clostridioides difficile toxin B [Units/volume] in Stool by Immunoassay
Short Name
C diff Tox B Stl IA-aCnc
Display Name
C. difficile toxin B IA Qn (Stl)
Consumer Name Alpha Get Info
Clostridioides difficile toxin B, Stool

Part Model Get Info

  • Component
    Clostridioides difficile toxin B
    LP14920-0
    • Analyte
      Clostridioides difficile toxin B
      LP14920-0
      • Component Numerator
        Clostridioides difficile toxin B
        LP14920-0
        • Component Numerator Core
          Clostridioides difficile toxin B
          LP14920-0
        • Component Numerator Core Suffix
          NULL
           
      • Component Denominator
        NULL
         
        • Component Denominator Core
          NULL
           
        • Component Denominator Core Suffix
          NULL
           
    • Challenge
      NULL
       
    • Adjustment
      NULL
       
    • Count
      NULL
       
  • Property
    ACnc
    LP6773-8
  • Time
    Pt
    LP6960-1
  • System
    Stool
    LP7604-4
    • System Core
      Stool
      LP7604-4
    • Super System
      NULL
       
  • Scale
    Qn
    LP7753-9
  • Method
    IA
    LP217197-5

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0f
Last Updated
Version 2.73 (MIN)
Change Reason
The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
Order vs. Observation
Both
Common Test Rank Get Info
16387

Language Variants Get Info

TagLanguageTranslation
cs-CZCzech (Czechia)Clostridioides difficile toxin B:Arbitrární koncentrace:Časový bod:Stolice:Kvantitativní:Imunoanalýza
de-DEGerman (Germany)Clostridioides difficile Toxin B:Arbiträre Konzentration:Zeitpunkt:Stuhl:Quantitativ:Immunoassay
el-GRGreek (Greece)Τοξίνη Β του Clostridioides difficile:ACnc:Pt:Κόπρανα:Qn:IA
Synonyms: ACnc B Clostridioides difficile IA MICRO Pt Qn Κόπρανα Τοξίνη Β του Clostridioides difficile Τοξίνη του Clostridioides difficile
es-ARSpanish (Argentina)toxina B de Clostridium difficile:concentración arbitraria:punto en el tiempo:materia fecal:cuantitativo:enzimoinmunoanálisis
es-ESSpanish (Spain)Clostridium difficile toxina B:Concentración arbitraria:Punto temporal:Heces:Qn:IA
Synonyms: Cuantitativo
es-MXSpanish (Mexico)Toxina B de Clostridioides difficile:Concentración arbitraria:Punto temporal:Heces:Cuantitativo:Inmunoensayo
et-EEEstonian (Estonia)Clostridium difficile toksiin B:Acnc:Pt:St:Qn:IA
Synonyms: Juhuslik Kvantitatiivne Roe
fr-CAFrench (Canada)Toxine B du clostridioides difficile:Concentration arbitraire:Temps ponctuel:Selles:Quantitatif:IA
fr-FRFrench (France)Clostridioides difficile toxine B:Arbitraire/Volume:Ponctuel:Selle:Numérique:Immunoanalyse
fr-BEFrench (Belgium)Toxine B du Clostridium difficile:Concentration arbitraire:Temps ponctuel:Selles:Quantitatif:IA
Synonyms: Clostridium difficile.Toxine B
it-ITItalian (Italy)Clostridium difficile, tossina B:ACnc:Pt:Feci:Qn:IA
Synonyms: Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio) Tossina B di Clostridium difficile Tossina di Clostridium difficile
ko-KRKorean (Korea, Republic Of)클로스트리디움 디피실리 독소 B:임의농도:검사시점:대변:정량:효소면역측정법
nl-NLDutch (Netherlands)Clostridioides difficile toxine B:eenheid/volume:moment:feces:kwantitatief:immunoassay
Synonyms: Clostridium difficile Clostridium difficile toxine Clostridium difficile toxine B IA ontlasting; feces
pt-BRPortuguese (Brazil)Clostridium difficile toxina B:ACnc:Pt:Fezes:Qn:Imunoensaio
Synonyms: ; C dif Tox B; C diff; C difficile; Arbitrary concentration; Point in time; Random; Stl; Feces; Faeces; Bowel movement; Fecal; Faecal; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Microbiology
ru-RURussian (Russian Federation)Clostridium difficile токсин B:ПроизвКонц:ТчкВрм:Фекалии:Колич:IA
Synonyms: Количественный Произвольная концентрация Точка во времени;Момент
tr-TRTurkish (Turkey)Clostridium difficile toksin B:SçKons:Zmlı:Dışkı:Kant:İA
Synonyms: Gaita; feçes İmmünölçüm, immünoassay
zh-CNChinese (China)艰难梭菌毒素 B:任意型浓度:时间点:大便:定量型:免疫测定法
Synonyms: B 型 任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度 便;大肠运动;排便;粪便;肠运动 免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 时刻;随机;随意;瞬间 艰难梭状芽胞杆菌;艰难芽孢梭菌 艰难梭状芽胞杆菌毒素 B;艰难梭状芽胞杆菌毒素 B 型;艰难梭菌毒素 B 型;艰难芽孢梭菌毒素 B;艰难芽孢梭菌毒素 B 型 艰难梭状芽胞杆菌毒素;艰难芽孢梭菌毒素

Example Units

UnitSource
[arb'U]/mLExample UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=6365-1