6366-9

Clostridioides difficile toxin B [Units/volume] in Specimen by Immunoassay

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Part Description

LP14920-0 Clostridioides difficile toxin B
Clostridium difficile toxin B is a toxin produced by the bacteria Clostridium difficile. C. difficile produces two major kinds of toxins that are very potent and lethal; an enterotoxin (Toxin A) and a cytotoxin (Toxin B, this protein). Early studies suggested that toxin A (also known as TcdA) is the major toxin protein causing antibiotic-associated diarrhea (AAD); however, within the last decade it has been shown that Toxin B (or TcdB) plays a more important role in disease than anyone had forecasted. Toxin B has been identified as the major virulence factor that causes the opening of tight junctions of intestinal epithelial cells, which enables toxin to increase vascular permeability and induce hemorrhaging. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Clostridium difficile toxin B

Reference Information

Type	Source	Reference
Article	NCBI PubMed	Manabe YC, Vinetz JM, Moore RD, Merz C, Charache P, Bartlett JG. Clostridium difficile colitis: an efficient clinical approach to diagnosis. Ann Intern Med. 1995 Dec 1;123(11):835-40. Link to PubMed

LOINC Names Get Info

Fully-Specified Name: Clostridioides difficile toxin B:ACnc:Pt:XXX:Qn:IA
Long Common Name: Clostridioides difficile toxin B [Units/volume] in Specimen by Immunoassay
Short Name: C diff Tox B Spec IA-aCnc
Display Name: C. difficile toxin B IA Qn (Specimen)
Consumer Name Alpha Get Info: Clostridioides difficile toxin B, Specimen

Part Model Get Info

Component
Clostridioides difficile toxin B
LP14920-0
- Analyte
  Clostridioides difficile toxin B
  LP14920-0
  - Component Numerator
    Clostridioides difficile toxin B
    LP14920-0
    - Component Numerator Core
      Clostridioides difficile toxin B
      LP14920-0
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
ACnc
LP6773-8
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
XXX
LP7735-6
- System Core
  XXX
  LP7735-6
- Super System
  NULL
Scale
Qn
LP7753-9
Method
IA
LP217197-5

Basic Attributes

Class: MICRO
Type: Laboratory
First Released: Version 1.0f
Last Updated: Version 2.69 (MIN)
Change Reason: The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016; Updated genus name from Clostridium to Clostridioides based on current (2019) accepted nomenclature for this genus [PMID:27370902].
Order vs. Observation: Both

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Clostridioides difficile toxin B:Arbitrární koncentrace:Časový bod:XXX:Kvantitativní:Imunoanalýza
de-DE	German (Germany)	Clostridioides difficile Toxin B:Arbiträre Konzentration:Zeitpunkt:XXX:Quantitativ:Immunoassay
el-GR	Greek (Greece)	Τοξίνη Β του Clostridioides difficile:ACnc:Pt:XXX:Qn:IA Synonyms: ACnc B Clostridioides difficile IA MICRO Pt Qn XXX Τοξίνη Β του Clostridioides difficile Τοξίνη του Clostridioides difficile
es-AR	Spanish (Argentina)	toxina B de Clostridium difficile:concentración arbitraria:punto en el tiempo:XXX:cuantitativo:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Clostridium difficile toxina B:Concentración arbitraria:Punto temporal:XXX:Qn:IA Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Toxina B de Clostridioides difficile:Concentración arbitraria:Punto temporal:XXX:Cuantitativo:Inmunoensayo
et-EE	Estonian (Estonia)	Clostridium difficile toksiin B:Acnc:Pt:XXX:Qn:IA Synonyms: Juhuslik Kvantitatiivne Täpsustamata materjal
fr-CA	French (Canada)	Toxine B du clostridioides difficile:Concentration arbitraire:Temps ponctuel:XXX:Quantitatif:IA
fr-FR	French (France)	Clostridioides difficile toxine B:Arbitraire/Volume:Ponctuel:Milieux divers:Numérique:Immunoanalyse
fr-BE	French (Belgium)	Toxine B du Clostridium difficile:Concentration arbitraire:Temps ponctuel:XXX:Quantitatif:IA Synonyms: Clostridium difficile.Toxine B
it-IT	Italian (Italy)	Clostridium difficile, tossina B:ACnc:Pt:XXX:Qn:IA Synonyms: Concentrazione Arbitraria Immunoassay Microbiologia Punto nel tempo (episodio) Tossina B di Clostridium difficile Tossina di Clostridium difficile
ko-KR	Korean (Korea, Republic Of)	클로스트리디움 디피실리 독소 B:임의농도:검사시점:XXX:정량:효소면역측정법
nl-NL	Dutch (Netherlands)	Clostridioides difficile toxine B:eenheid/volume:moment:XXX:kwantitatief:immunoassay Synonyms: Clostridium difficile Clostridium difficile toxine Clostridium difficile toxine B IA
pt-BR	Portuguese (Brazil)	Clostridium difficile toxina B:ACnc:Pt:XXX:Qn:Imunoensaio Synonyms: ; C dif Tox B; C diff; C difficile; Arbitrary concentration; Point in time; Random; Misc; Miscellaneous; Unspecified; Other; Quantitative; QNT; Quant; Quan; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Microbiology
ru-RU	Russian (Russian Federation)	Clostridium difficile токсин B:ПроизвКонц:ТчкВрм:XXX:Колич:IA Synonyms: Количественный Произвольная концентрация Точка во времени;Момент
tr-TR	Turkish (Turkey)	Clostridium difficile toksin B:SçKons:Zmlı:XXX:Kant:İA Synonyms: İmmünölçüm, immünoassay
zh-CN	Chinese (China)	艰难梭菌毒素 B:任意型浓度:时间点:XXX:定量型:免疫测定法 Synonyms: B 型不明的;其他;将在相应消息内其他部分之中加以详细说明;未作详细说明的;未作说明的;未做说明的标本;未加规定的;未加说明的标本;杂项任意型浓度(单位体积);任意浓度;单位体积的任意单位数;人工型浓度免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验可用数量表示的;定量性;数值型;数量型;连续数值型标尺微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体）时刻;随机;随意;瞬间艰难梭状芽胞杆菌;艰难芽孢梭菌艰难梭状芽胞杆菌毒素 B;艰难梭状芽胞杆菌毒素 B 型;艰难梭菌毒素 B 型;艰难芽孢梭菌毒素 B;艰难芽孢梭菌毒素 B 型艰难梭状芽胞杆菌毒素;艰难芽孢梭菌毒素

Example Units

Unit	Source
[arb'U]/mL	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.