Version 2.80

Part Description

LP14255-1   Cytomegalovirus
Cytomegalovirus is a member of the family Herpesviridae and also known as Human Herpesvirus-5 (HHV-5). It contains a linear double-stranded DNA encased in an icosahedral capsid that is surrounded by a viral envelope. It replicates slowly and may take weeks for the infection to become visible microscopically. Its life cycle includes a lytic and a latent phase. During the lytic phase the cytoskeleton of the infected cell is disrupted and becomes very large. The enlarged cell eludes detection by natural killer (NK) cells by encoding UL16. UL16 is a protein that binds to the ligand NDG2D which is a surface receptor on NK cells and, when blocked, prevents the CMV infected cell from apoptotic signaling to NK cells to destroy it.[https://pedclerk.bsd.uchicago.edu/page/cytomegalovirus-cmv] In the US one in three children are infected by CMV by the age of five and over half of adults are infected by age 40. Infection with CMV is mostly asymptomatic. Symptoms when present include fever, sore throat, fatigue, swollen glands. CMV can occasionally lead to mononucleosis or hepatitis. Immunocompromised patients experience much more acute symptoms that can affect the eyes, lungs, liver, esophagus, stomach, and intestines. For babies born with CMV, involvement with the brain, spleen, lung, liver can occur. In addition, there may be growth problems and hearing loss which is the most common symptom in congenital CMV infection. CMV is transmitted in urine, saliva, blood, tears, semen and breast milk by direct contact. Normally no treatment is necessary, but for severe cases medication is available.[https://www.cdc.gov/cmv/overview.html] Source: Regenstrief LOINC

Fully-Specified Name

Component
Cytomegalovirus Ag
Property
PrThr
Time
Pt
System
Ser/Plas
Scale
Ord
Method
IF

Additional Names

Long Common Name
Cytomegalovirus Ag [Presence] in Serum or Plasma by Immunofluorescence
Short Name
CMV Ag SerPl Ql IF
Display Name
CMV Ag IF Ql
Consumer Name Alpha Get Info
Cytomegalovirus (CMV) antigen, Blood

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0f
Last Updated
Version 2.64 (MAJ)
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; Updated System from Ser to Ser/Plas since this test can also be done on plasma.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Cytomegalie-Virus Ag:Nachweis oder Schwellenwert:Zeitpunkt:Serum oder Plasma:Ordinal:Immunfluoreszenztest
Synonyms: CMV
el-GR Greek (Greece) Κυτταρομεγαλοϊός Αντιγόνο:PrThr:Pt:Ορός/Πλάσμα:Ord:Ανοσοφθορισμός
Synonyms: PrThr Κυτταρομεγαλοϊός
es-AR Spanish (Argentina) [antígeno de] citomegalovirus [Ag]:concentración arbitraria:punto en el tiempo:suero:ordinal:inmunofluorescencia
es-MX Spanish (Mexico) Citomegalovirus Ag:Presencia o umbral:Punto temporal:Suero o Plasma:Ordinal:Inmunofluorescencia (IF)
es-ES Spanish (Spain) Citomegalovirus Antígeno:PrThr:Punto temporal:Suero o Plasma:Ord:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Tsütomegaloviirus antigeen:PrThr:Pt:S/P:Ord:IF
Synonyms: Järgarvuline Juhuslik Plasma Seerum Seerum või plasma
fr-CA French (Canada) Cytomégalovirus, Ag:Présence-Seuil:Temps ponctuel:Sérum/Plasma:Ordinal:Immunofluorescence
fr-BE French (Belgium) Cytomégalovirus Ag:PrThr:Temps ponctuel:Sérum/Plasma:Ordinal:Immunofluorescence
Synonyms: Antigène CMV
fr-FR French (France) Cytomégalovirus Ag:Présence/Seuil:Ponctuel:Sérum/Plasma:Qualitatif:Immunofluorescence
it-IT Italian (Italy) Citomegalovirus, Ag:PrThr:Pt:Siero/Plasma:Ord:IF
Synonyms: Immunofluorescenza (IF) Microbiologia Plasma Presenza o Soglia Punto nel tempo (episodio) Siero Siero o Plasma
ko-KR Korean (Korea, Republic Of) 거대세포바이러스 항원:임의농도:검사시점:혈청:순위척도:면역형광
nl-NL Dutch (Netherlands) Cytomegalovirus Ag:aanwezigheid:moment:serum of plasma:ordinaal:immunofluorescentie
Synonyms: antigeen IF
pl-PL Polish (Poland) Wirus cytomegalii Ag:granica wykrywalności:punkt w czasie:surowica lub osocze:półilościowy:immunofluorescencja
Synonyms: Antygen wirusa cytomegalii Cytomegalowirus
pt-BR Portuguese (Brazil) Citomegalovírus Ag:ACnc:Pt:Soro:Ord:Imunofluorescência
Synonyms: ; CMV; Cytomgal; Cytomegalo virus; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; ACIF; FA; Fluorescent antibody; Immune fluorescence; Fluoresent; Immunoflour; Immunofluor; Immunofluorescence; IFA; Time Resolved Fluorescence; Anticomplement Immunofluorescence; TRF; Antigen; Antigens; Microbiology; DFA
ru-RU Russian (Russian Federation) Цитомегаловирус Аг:PrThr:ТчкВрм:Сыв/Плаз:Пор:ИФ
Synonyms: Иммунофлюоресценция (ИФ) Плазма Порядковый Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Cytomegalovirus Ag:MevcEşik:Zmlı:Ser/Plaz:Srl:IF
Synonyms: İmmünflorerans Mevcut
zh-CN Chinese (China) 巨细胞病毒 抗原:存在情况或阈值:时间点:血清/血浆:序数型:免疫荧光法
Synonyms: Ag Ag IF CMV Ag CMV 抗原 CMV;涎腺病毒;细胞巨化病毒;细胞肥大病毒 DFA IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 巨细胞病毒 Ag 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗原免疫荧光检测 抗原免疫荧光测定 时刻;随机;随意;瞬间 直接免疫荧光分析 直接免疫荧光检测 直接免疫荧光测定 血清或血浆

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=6377-6