LOINC
Version 2.73

65759-3T-cell subsets CD4 and CD8 panel - BloodActive

Term Description

In this test panel both CD3+ and CD4+ are required to recognize CD4 T cells (helper cells), and both CD3+ and CD8+ to recognize CD8 T cells (suppressor cells). The measurement of Helper T-cell levels has been used to establish decision points for initiating P. jiroveci prophylaxis, antiviral therapy and to monitor the efficacy of treatment. The Public Health Service (PHS) has recommended that Helper T-cell levels be monitored every three to six months in all HIV-infected persons.

During HIV infection, antiviral therapy is often initiated when the absolute CD4 T cell count drops below 500 cells/µL. When the absolute CD4 T cell count drops below 200 cells/µL, therapeutic prophylaxis against PCP and other opportunistic infections may be initiated. When the absolute CD4 T cell count drops below 100 cells/µL, prophylaxis against Mycobacterium avium complex is recommended. (from ARUP, modified)
Source: Regenstrief LOINC

Part Descriptions

LP14443-3   CD4
Found on helper T-cells; weakly expressed on monocytes.
Associated with some mature T-cell neoplasms, including most cases of T-cell CLL/prolymphocytic leukemia, peripheral
T-cell lymphoma, adult T-cell leukemia/lymphoma and Sézary syndrome/mycosis fungoides Source: Regenstrief LOINC

LP17729-2   CD8
Found on T-suppressor/cytotoxic cells and some Natural Killer cells; Associated with some mature T-cell neoplasms; Large granular lymphocytosis Source: Regenstrief LOINC

Panel Hierarchy
Details for each LOINC in Panel LHC-Forms

LOINC Name R/O/C Cardinality Example UCUM Units
65759-3 T-cell subsets CD4 and CD8 panel - Blood
Indent26474-7 Lymphocytes [#/volume] in Blood C 10*3/uL
Indent27071-0 CD45 (Lymphs) cells [#/volume] in Blood C /uL
Indent8122-4 CD3 cells [#/volume] in Blood R /uL
Indent8124-0 CD3 cells/100 cells in Blood O %
Indent24467-3 CD3+CD4+ (T4 helper) cells [#/volume] in Blood R /uL
Indent8123-2 CD3+CD4+ (T4 helper) cells/100 cells in Blood O %
Indent14135-8 CD3+CD8+ (T8 suppressor) cells [#/volume] in Blood R /uL
Indent8101-8 CD3+CD8+ (T8 suppressor) cells/100 cells in Blood O %
Indent54218-3 CD3+CD4+ (T4 helper) cells/CD3+CD8+ (T8 suppressor cells) cells [# Ratio] in Blood O %

Fully-Specified Name

Component
T-cell subsets CD4 & CD8 panel
Property
-
Time
Pt
System
Bld
Scale
-
Method

Additional Names

Short Name
T-cell subsets CD4+CD8 pnl Bld
Display Name
T-cell subsets CD4 and CD8 panel (Bld)
Consumer Name Alpha
T-cell Subsets CD4 and CD8 Panel, Blood

Basic Attributes

Class
PANEL.CELLMARK
Type
Laboratory
First Released
Version 2.36
Last Updated
Version 2.73
Order vs. Observation
Order
Common US Lab Results Rank
2356
Common Orders Rank
196
Panel Type
Panel

Language Variants Get Info

zh-CNChinese (China)
T-细胞亚群 CD4 与 CD8 组套:-:时间点:全血:-:
nl-NLDutch (Netherlands)
T-cell subsets CD4 & CD8 panel:-:moment:bloed:-:
fr-FRFrench (France)
Sous-populations lymphocytaires CD4 et Cd8 panel:-:Ponctuel:Sang:-:
it-ITItalian (Italy)
Subsets CD4 & CD8 di linfociti T, panel:-:Pt:Sangue:-:
ru-RURussian (Russian Federation)
T-клетки подмножества CD4 & CD8 панель:-:ТчкВрм:Кр:-:
es-MXSpanish (Mexico)
Panel de subconjuntos de células T CD4 y CD8:-:Punto temporal:Sangre:-:
es-ESSpanish (Spain)
Perfil de subpoblaciones celulares T CD4 y CD8:Propiedades mixtas (sólo paneles):Punto temporal:Sangre:-:

LOINC FHIR® API Example - CodeSystem and Questionnaire Requests Get Info

https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=65759-3 https://fhir.loinc.org/Questionnaire/?url=http://loinc.org/q/65759-3