Version 2.78

Part Descriptions

LP17129-5   Leptospira interrogans
A genus of question mark-shaped bacteria spirochetes which is found in fresh water that is contaminated by animal urine. It causes LEPTOSPIROSIS. Source: National Library of Medicine, MeSH 2006

LP17129-5   Leptospira interrogans
Leptospira is a flexible, spiral-shaped, Gram-negative spirochete with internal flagella. Leptospira interrogans has many serovars based on cell surface antigens. Most leptospirosis infections initially present with an acute onset of fever, headache and muscle pain, which symptoms last about a week. The three organ systems most frequently involved with more significant illness are the central nervous system, kidneys, and liver, and jaundice occurs with severe infections. With the appearance of antileptospiral antibodies, the acute phase of the disease subsides and leptospires can no longer be isolated from the blood. The disease is usually biphasic, with the acute phase followed by an immune phase, which occurs after an asymptomatic period of several days. The immune phase is associated with fever and central nervous system involvement, specifically meningitis. Leptospires appear in the urine during this phase and are shed for various periods depending on the host. Severe leptospirosis is associated with progressive impairment of hepatic and renal function, and renal failure is the most common cause of death.
Leptospirosis is a worldwide zoonosis with a variety of animal hosts. The primary reservoir is wild animals such as rodents, which can shed leptospires throughout their lifetimes. Domestic animals are also an important source of human infections. The disease is more widespread in tropical countries. Direct or indirect contact with urine containing virulent leptospires is the major means by which leptospirosis is transmitted.
Leptospira species, which include L. interrogans, L. autumnalis, L. borgpetersenii, and L. weili are further divided into more than 200 serotypes based on their antigenic composition. The more severe form of leptospirosis is frequently associated with the icterohaemorrhagiae serotype and is often referred to as Weil's disease. [NCBI Books: NBK8451] Source: Regenstrief LOINC, NCBI Books: NBK8451

Fully-Specified Name

Component
Leptospira interrogans Ag
Property
PrThr
Time
Pt
System
Tiss
Scale
Ord
Method
IF

Additional Names

Short Name
L inter Ag Tiss Ql IF
Display Name
L. interrogans Ag IF Ql (Tiss)
Consumer Name Alpha Get Info
Leptospira interrogans antigen, Tissue

Basic Attributes

Class
MICRO
Type
Laboratory
First Released
Version 1.0g
Last Updated
Version 2.56
Change Reason
The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.
Order vs. Observation
Both

Member of these Groups Get Info

LOINC Group Group Name
LG41636-8 Leptospira

Language Variants Get Info

Tag Language Translation
de-DE German (Germany) Leptospira interrogans Ag:Nachweis oder Schwellenwert:Zeitpunkt:Gewebe:Ordinal:Immunfluoreszenztest
es-AR Spanish (Argentina) [antígeno de] Leptospira interrogans [Ag]:concentración arbitraria:punto en el tiempo:tejido, no especificado:ordinal:inmunofluorescencia
es-ES Spanish (Spain) Leptospira interrogans Antígeno:PrThr:Punto temporal:Tejido:Ord:Inmunofluorescencia (IF)
es-MX Spanish (Mexico) Leptospira interrogans Ag:Presencia o umbral:Punto temporal:Tejido y frotis:Ordinal:Inmunofluorescencia (IF)
et-EE Estonian (Estonia) Leptospira interrogans antigeen:PrThr:Pt:Tis:Ord:IF
Synonyms: Järgarvuline Juhuslik Kude
fr-CA French (Canada) Leptospira interrogans, Ag:Présence-Seuil:Temps ponctuel:Tissu:Ordinal:Immunofluorescence
fr-FR French (France) Leptospira interrogans Ag:Présence/Seuil:Ponctuel:Tissu:Qualitatif:Immunofluorescence
fr-BE French (Belgium) Leptospira interrogans Ag:PrThr:Temps ponctuel:Tissu:Ordinal:Immunofluorescence
Synonyms: Antigène
it-IT Italian (Italy) Leptospira interrogans, Ag:PrThr:Pt:Tessuto:Ord:IF
Synonyms: Immunofluorescenza (IF) Microbiologia Presenza o Soglia Punto nel tempo (episodio) Tessuto & Strisci
ko-KR Korean (Korea, Republic Of) 렙토스피라 인테로간스 항원:임의농도:검사시점:조직:순위척도:면역형광
nl-NL Dutch (Netherlands) Leptospira interrogans Ag:aanwezigheid:moment:weefsel en uitstrijkjes:ordinaal:immunofluorescentie
Synonyms: antigeen IF
pt-BR Portuguese (Brazil) Leptospira interrogans Ag:ACnc:Pt:Tecido:Ord:Imunofluorescência
Synonyms: ; L inter; L interrogans; Arbitrary concentration; Point in time; Random; Tissue; Ql; Ordinal; QL; Qualitative; Qual; Screen; ACIF; FA; Fluorescent antibody; Immune fluorescence; Fluoresent; Immunoflour; Immunofluor; Immunofluorescence; IFA; Time Resolved Fluorescence; Anticomplement Immunofluorescence; TRF; Antigen; Antigens; Leptospirosis; Microbiology; DFA
ru-RU Russian (Russian Federation) Leptospira interrogans Аг:PrThr:ТчкВрм:Тк:Пор:ИФ
Synonyms: Иммунофлюоресценция (ИФ) Порядковый Ткань и мазки Точка во времени;Момент
tr-TR Turkish (Turkey) Leptospira interrogans Ag:MevcEşik:Zmlı:Doku:Srl:IF
Synonyms: Antijen İmmünflorerans Mevcut
zh-CN Chinese (China) 致病性钩端螺旋体 抗原:存在情况或阈值:时间点:组织与涂片:序数型:免疫荧光法
Synonyms: Ag Ag IF DFA IFA法;IF法;抗补体免疫荧光法;时间分辨荧光法;荧光原位杂交技术;荧光原位杂交法;荧光抗体 依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型 存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值） 微生物学;微生物学试验;微生物学试验（培养、DNA、抗原及抗体） 抗原免疫荧光检测 抗原免疫荧光测定 时刻;随机;随意;瞬间 未作说明的组织;组织;组织 & 涂片 直接免疫荧光分析 直接免疫荧光检测 直接免疫荧光测定 细螺旋体 细螺旋体属 细螺旋体病 致病性钩端螺旋体 Ag 螺旋体 钩体 钩体;问号钩端螺旋体 钩体病 钩端螺旋体属 钩端螺旋体病 问号钩端螺旋体 Ag 问号钩端螺旋体抗原

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