66148-8

Mononuclear cells/Leukocytes in Pleural fluid from Fetus by Manual count

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Part Descriptions

LP157588-7 Leukocytes
Leukocytes or white blood cells (WBCs) are immune cells that fight infection, neoplasms and other inflammatory conditions, and mediate allergic responses. There are five types of WBCs normally present in the circulation that are all derived from a similar stem cell in the bone marrow. The five type of WBCs are divided into two groups based on the presence or absence of granules in the cytoplasm. The granulocytes include the neutrophils, basophils and eosinophils. The non-granulocytes include the lymphocytes and the monocytes. The neutrophils fight infection by ingesting and digesting bacteria. Eosinophils and basophils respond to allergic reactions and are capable of ingesting antigen-antibody complexes. Monocytes phagocytose bacteria and release interferon to stimulate the immune system. Lymphocytes are divided into T-cells and B-cells. T-cell immunity is cellular and involves the activation of phagocytes and B-cell immunity uses antibodies to fight infection. Both elevated and low leukocyte counts can be markers of infection and malignancy, and low leukocyte counts are associated with a variety of primary and secondary immunodeficiencies, depending on the WBC type(s) that are out of range. (Mosby's manual of diagnostic and laboratory tests, Kathleen Deska Pagana; Timothy James Pagana, Elsevier St. Louis, Mo ©2010) Source: Regenstrief LOINC

LP17839-9 Mononuclear cells
A Peripheral Blood Mononuclear Cell (PBMC) is a blood cell having a round nucleus, such as a lymphocyte or a monocyte. These blood cells are a critical component in the immune system to fight infection and adapt to intruders. The lymphocyte population consists of T cells (CD4 and CD8 positive ~75%), B cells and NK cells (~25% combined).

These cells are often extracted from whole blood using ficoll, a hydrophilic polysaccharide that separates layers of blood, with monocytes and lymphocytes forming a buffy coat under a layer of plasma. This buffy coat contains the PBMCs. Additionally, PBMC can be extracted from whole blood using a hypotonic lysis which will preferentially lyse red blood cells. This method results in neutrophils and other polymorphonuclear (PMN) cells which are important in innate immune defense to be obtained.

PBMCs are widely used in research and clinical uses every day. HIV research uses them because PBMCs include CD4+ cells, the cells HIV infects. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Mononuclear cell

LOINC Names Get Info

Fully-Specified Name: Mononuclear cells/Leukocytes:NFr:Pt:Plr fld^Fetus:Qn:Manual count
Long Common Name: Mononuclear cells/Leukocytes in Pleural fluid from Fetus by Manual count
Short Name: Mononuc Cells NFr Plr Fetus Manual
Display Name: Mononuclear cells/Leukocytes Manual cnt (Pleur fld fetus)
Consumer Name Alpha Get Info: Fetal Mononuclear cells/White Blood Cells

Part Model Get Info

Component
Mononuclear cells/leukocytes
LP286569-1
- Analyte
  Mononuclear cells/leukocytes
  LP286569-1
  - Component Numerator
    Mononuclear cells
    LP17839-9
    - Component Numerator Core
      Mononuclear cells
      LP17839-9
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    Leukocytes
    LP157588-7
    - Component Denominator Core
      Leukocytes
      LP157588-7
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
NFr
LP6838-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Plr fld^Fetus
LP281818-7
- System Core
  Plr fld
  LP7486-6
- Super System
  Fetus
  LP6982-5
Scale
Qn
LP7753-9
Method
Manual count
LP6377-8

Basic Attributes

Class: HEM/BC
Type: Laboratory
First Released: Version 2.38
Last Updated: Version 2.79 (NAM)
Change Reason: Release 2.79: COMPONENT: Triggered by Coll w SCT: This is a specific fraction case where the denominator is percentage or /100. Because the logic is that the percentage piece is captured by Property: NFr (Numeric Fraction), and by Unit: %, therefore, it is redundant to include "100" in the component;
Order vs. Observation: Observation

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Buňky mononukleární/100 leukocytů:Početní podíl:Časový bod:Pleurální tekutina^Plod:Kvantitativní:Počítání manuálně
el-GR	Greek (Greece)	Μονοπύρηνα κύτταρα/Λευκοκύτταρα:NFr:Pt:Υπεζωκοτικό υγρό^Έμβρυο:Qn:Χειροκίνητη καταμέτρηση Synonyms: HEM/BC NFr Pt Qn Έμβρυο Κύτταρα Λευκοκύτταρα Μη αυτόματη Μονοπύρηνα κύτταρα Υπεζωκοτικό υγρό Χειροκίνητη καταμέτρηση
es-ES	Spanish (Spain)	Mononucleares/Leucocitos:Fracción numérica:Punto temporal:Líquido pleural^Feto:Qn:Contaje manual Synonyms: Cuantitativo
es-MX	Spanish (Mexico)	Células mononucleares / 100 leucocitos:Fracción numérica:Punto temporal:Plr fld ^ Feto:Cuantitativo:Conteo manual
fr-CA	French (Canada)	Cellules mononucléaires/Leucocytes:Fraction numérique:Temps ponctuel:Liquide pleural^Foetus:Quantitatif:Numération manuelle
fr-FR	French (France)	Cellules mononucléées/leucocytes:Fraction de nombres:Ponctuel:Liquide pleural^foetus:Numérique:Comptage manuel
it-IT	Italian (Italy)	Cellule mononucleari/Leucociti:NFr:Pt:Liquido pleurico^feto:Qn:Conta manuale Synonyms: Ematologia (coagulazione) conta differenziale Frazione numerica Liquido pleurico Punto nel tempo (episodio)
nl-NL	Dutch (Netherlands)	mononucleaire cellen/leukocyten:getalsfractie:moment:pleuravocht^foetus:kwantitatief:manuele telling Synonyms: handmatige methode handmatige telling
pl-PL	Polish (Poland)	Mononuklearne komórki/leukocyty:frakcja liczbowa:punkt w czasie:płyn opłucnowy^płód:ilościowy:zliczanie ręczne Synonyms: Leukocyty Mononuklearne komórki Mononuklearne komórki/leukocyty
ru-RU	Russian (Russian Federation)	Мононуклеарные клетки/Лейкоциты:КолДоля:ТчкВрм:Плевр ждк^Плод:Колич:Ручной подсчет Synonyms: Количественный Количество отношение Плевральная жидкость Точка во времени;Момент
tr-TR	Turkish (Turkey)	Mononükleer hücreler/Lökosit:SayFr:Zmlı:Plvr sv^Fetus:Kant:Manuel sayım Synonyms: El ile
zh-CN	Chinese (China)	单个核细胞/白细胞:计数型分数:时间点:胸膜液^胎儿:定量型:手工计数方法 Synonyms: Leuc;Leuk;Lkcs;WBC;WBCs;白细胞;White blood cell;WBC;白细胞类;白细胞类髓系细胞;白血球;白血细胞;白细胞数人工计数;人工计数方法;人工计数法;手工计数;手工计数法单个核可用数量表示的;定量性;数值型;数量型;连续数值型标尺实验室手工方法;手工;手工法;手工类实验室方法;手工类方法;手工类检验方法数量型分数;数量或计数型分数;数量型分数或计数型分数时刻;随机;随意;瞬间细胞含量;细胞性;细胞性质;细胞构成;细胞类胎;超系统 - 胎儿胸腔积液;胸水;胸膜穿刺液;胸膜腔积水;胸膜腔积液胸膜液（胸腔积液、胸水、胸膜穿刺液、胸膜腔积水、胸膜腔积液）.胎儿（胚胎、胎）血液学/细胞计数;血液学与细胞计数

Example Units

Unit	Source
%	Example UCUM Units

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.