Version 2.80

Status Information

Status
DISCOURAGED
Comment
These were created for the sole purpose of facilitating use of LOINC for submissions for medication approval to the FDA and should not be used in routine laboratory reporting.

Term Description

Identifies a morning specimen when cortisol is at its highest point in a circadian cycle - often considered to be 8AM. Some laboratories will call this "8AM" specimen, but specimens in the range of 7AM to 9AM are acceptable. The peak time may have to be adjusted for patients on night or evening shifts because their circadian rhythms can shift with their sleeping time.

Part Descriptions

LP14161-1   Cortisol
Cortisol is a glucocorticoid produced in the adrenal cortex. A synthetic version of this same chemical is called hydrocortisone and manufactured as medication. Cortisol is not to be confused with cortisone, a closely related compound with much less (PubChem calls it "inactive") biologic activity. Cortisone is also offered as a drug, and it is converted to cortisol (the active form) in the liver. They both have a circadian rhythm with peak in the AM (around 8AM) and trough in the evening (around midnight), but this shifts according to sleep habits (work shifts). The morning measurement, which should be high, is most useful for diagnosing Addison's disease (too little cortisol) and the evening measurement, which should be low, is the most useful for diagnosing Cushing's disease (too much cortisol). Salivary cortisol may be a more sensitive measure than serum or plasma. Source: Regenstrief Help

LP156505-2   AM peak specimen
Identifies a morning specimen when analyte is at its highest point in a circadian cycle - often considered to be 8AM. Some laboratories will call this "8AM" specimen, but specimens in the range of 7AM to 9AM are acceptable. The peak time may have to be adjusted for patients on night or evening shifts because their circadian rhythms can shift with their sleeping time. Source: Regenstrief Help

Fully-Specified Name

Component
Cortisol^AM peak specimen
Property
MSCnc
Time
Pt
System
Ser/Plas
Scale
Qn
Method

Additional Names

Long Common Name
Cortisol [Mass or Moles/volume] in Serum or Plasma --AM peak specimen
Short Name
Cortis AM peak SerPl-msCnc
Display Name
Cortisol AM peak specimen [Mass or moles/Vol]
Consumer Name Alpha Get Info
Cortisol AM Peak specimen, Blood

Basic Attributes

Class
CHEM
Type
Laboratory
First Released
Version 2.38
Last Updated
Version 2.70 (MIN)
Change Reason
To avoid two ways (AM and morning) of saying the same thing. We chose AM because it is shorter. 'Peak' clarifies that specimen is collected when cortisol is expected to be at the highest level.
Order vs. Observation
Both

Language Variants Get Info

Tag Language Translation
el-GR Greek (Greece) Κορτιζόλη^Δείγμα μέγιστης στάθμης π.μ.:MSCnc:Pt:Ορός/Πλάσμα:Qn:
Synonyms: Am MSCnc Κορτιζόλη
es-ES Spanish (Spain) Cortisol^AM muestra pico:Razón de masa o sustancia:Punto temporal:Suero o Plasma:Qn:
Synonyms: Cuantitativo
es-MX Spanish (Mexico) Muestra de pico de cortisol ^ AM:Concentración de masa o sustancia:Punto temporal:Suero o Plasma:Cuantitativo:
it-IT Italian (Italy) Cortisolo^Picco campione AM:MSCnc:Pt:Siero/Plasma:Qn:
Synonyms: Campione Chimica Concentrazione Sostanza o Massa Picco di campione mattutino Picco TDM Plasma Punto nel tempo (episodio) Siero Siero o Plasma
nl-NL Dutch (Netherlands) cortisol^ochtend-piekmonster:massa of stof/volume:moment:serum of plasma:kwantitatief:
Synonyms: voormiddag-piekmonster
ru-RU Russian (Russian Federation) Кортизол^Утренний пиковый образец:МасМольКонц:ТчкВрм:Сыв/Плаз:Колич:
Synonyms: Количественный Массовая или Молярная Концентрация Плазма Проба, взятая с 7 до 9 часов утра например крови на кортизол в эти часы концентрация кортизола максимальна Сыворотка Сыворотка или Плазма Точка во времени;Момент
tr-TR Turkish (Turkey) Kortizol^Sabah tepe örneği:KütlSubKons:Zmlı:Ser/Plaz:Kant:
zh-CN Chinese (China) 皮质醇^早晨峰值标本:质量或物质的量浓度:时间点:血清/血浆:定量型:
Synonyms: 17-羟皮质甾酮;17-羟皮质酮;化合物 F;可的索;氢化可的松;皮质甾醇;考的索 Am 型;上午 一剂药物的后剂量(Postdose);剂量药物的后剂量(Postdose);后剂量(Postdose);峰值;曲线上的最大值;最高点;治疗药物监测 - 波峰 化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类 受检物 可用数量表示的;定量性;数值型;数量型;连续数值型标尺 早晨高峰标本;早晨高值标本 时刻;随机;随意;瞬间 标本（样本、样品、试样） 样品 样本 血清或血浆 试样 质量或摩尔浓度;质量或摩尔浓度(单位体积);质量或物质的量浓度(单位体积)

Example Units

Unit Source
u/dL;nmol/L Example UCUM Units

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=66735-2