6787-6

Kappa light chains [Presence] in Serum by Immunoassay

Active

Part Description

LP15030-7 Immunoglobulin light chains.kappa
All immunoglobulins contain two polypeptide chains: a long (heavy) and a short (light) chain. The two chains interact via disulfide bonds. There are two types of light chains, named kappa and lambda. Serum free light chain (SFLC) testing, a kappa/lambda ratio and a protein electrophoresis test are done to help detect, diagnose and monitor plasma cell disorders (dyscrasias) including multiple myeloma and primary amyloidosis. Normal readings are seen when there is a kappa/lambda ratio of approximately 0.26 to 1.65 and free light chains are present in the blood at low levels. Increased kappa free light chains and an increased kappa/lambda ratio are present with plasma cell disorders that produce excess monoclonal kappa light chains. The tests can also be used to monitor response to treatment. An increase in serum free light chains along with an abnormal kappa/lambda ratio may indicate primary amyloidosis; biopsy of affected tissue is typically used for confirmation of diagnosis. PMID: 6802926 ] Source: Regenstrief LOINC

LOINC Names Get Info

Fully-Specified Name: Immunoglobulin light chains.kappa:PrThr:Pt:Ser:Ord:IA
Long Common Name: Kappa light chains [Presence] in Serum by Immunoassay
Short Name: Kappa LC Ser Ql IA
Display Name: Immunoglobulin light chains.kappa IA Ql (S)
Consumer Name Alpha Get Info: Immunoglobulin light chains.kappa, Blood

Part Model Get Info

Component
Immunoglobulin light chains.kappa
LP15030-7
- Analyte
  Immunoglobulin light chains.kappa
  LP15030-7
  - Component Numerator
    Immunoglobulin light chains.kappa
    LP15030-7
    - Component Numerator Core
      Immunoglobulin light chains.kappa
      LP15030-7
    - Component Numerator Core Suffix
      NULL
  - Component Denominator
    NULL
    - Component Denominator Core
      NULL
    - Component Denominator Core Suffix
      NULL
- Challenge
  NULL
- Adjustment
  NULL
- Count
  NULL
Property
PrThr
LP217195-9
Time
Pt
LP6960-1
- Time Core
  Pt
  LP6960-1
- Time Modifier
  NULL
System
Ser
LP7567-3
- System Core
  Ser
  LP7567-3
- Super System
  NULL
Scale
Ord
LP7751-3
Method
IA
LP217197-5

Basic Attributes

Class: CHEM
Type: Laboratory
First Released: Version 1.0h(2)
Last Updated: Version 2.63 (MIN)
Change Reason: The PrThr property is used for LOINC terms whose results are reported using an ordered categorical scale, regardless of whether or not an internal threshold was used to make that determination. This change was approved by the Laboratory LOINC Committee in June 2016.; The EIA method, which was always intended to cover more than just enzyme-linked immunoassay and whose display name for the long common name has always been Immunoassay, was renamed IA in order to eliminate ambiguity about whether the method has a broader meaning than just enzyme-linked immunoassay. Likewise, EIA.rapid was renamed IA.rapid. These changes were approved by the Laboratory LOINC Committee in June 2016. Changed the LCN from 'Immunoglobulin light chains.kappa' to 'Kappa light chains' for readability.
Order vs. Observation: Both

Member of these Groups Get Info

LOINC Group	Group Name
LG9568-9	Immunoglobulin light chains.kappa\|PrThr\|Pt\|ANYBldSerPl

Language Variants Get Info

Tag	Language	Translation
cs-CZ	Czech (Czechia)	Ig lehké řetězce kappa:Přítomnost nebo práh:Časový bod:Sérum:Ordinální:Imunoanalýza
de-DE	German (Germany)	Immunglobulin Leichtketten.kappa:Nachweis oder Schwellenwert:Zeitpunkt:Serum:Ordinal:Immunoassay
el-GR	Greek (Greece)	Ελαφριές αλυσίδες ανοσοσφαιρίνης.κάπα:PrThr:Pt:Ορός:Ord:IA Synonyms: CHEM IA Ord PrThr Pt Ελαφρές αλυσίδες ανοσοσφαιρίνης Ελαφριές αλυσίδες ανοσοσφαιρίνης.κάπα Ορός
es-AR	Spanish (Argentina)	cadenas livianas de inmunoglobulina.kappa:concentración arbitraria:punto en el tiempo:suero:ordinal:enzimoinmunoanálisis
es-ES	Spanish (Spain)	Cadenas ligeras de las inmunoglobulinas.kappa:PrThr:Punto temporal:Suero:Ord:IA
es-MX	Spanish (Mexico)	Cadenas ligeras de inmunoglobulina kappa:Presencia o umbral:Punto temporal:Suero:Ordinal:Inmunoensayo
et-EE	Estonian (Estonia)	Immuunoglobuliini kerged ahelad.kapa:PrThr:Pt:S:Ord:IA Synonyms: Immuunglobuliinide kerged kapaahelad Järgarvuline Juhuslik Seerum
fr-CA	French (Canada)	Chaînes légères d'immunoglobulines.kappa:Présence-Seuil:Temps ponctuel:Sérum:Ordinal:IA
fr-FR	French (France)	Immunoglobuline chaines légères kappa:Présence/Seuil:Ponctuel:Sérum:Qualitatif:Immunoanalyse
fr-BE	French (Belgium)	Chaînes légères immunoglobulines.kappa:PrThr:Temps ponctuel:Sérum:Ordinal:IA Synonyms: LC LC. Kappa
it-IT	Italian (Italy)	Immunoglobuline, catene leggere.kappa:PrThr:Pt:Siero:Ord:IA Synonyms: Catene leggere delle immunoglobuline Catene leggere kappa delle immunoglobuline Chimica Immunoassay Presenza o Soglia Punto nel tempo (episodio) Siero
ko-KR	Korean (Korea, Republic Of)	카파면역글로불린 경쇄:임의농도:검사시점:혈청:순위척도:효소면역측정법
nl-NL	Dutch (Netherlands)	immunoglobuline lichte ketens.kappa:aanwezigheid:moment:serum:ordinaal:immunoassay Synonyms: IA
pl-PL	Polish (Poland)	Łańcuchy lekkie immunoglobuliny.kappa:granica wykrywalności:punkt w czasie:surowica:uporządkowany:metoda immunologiczna Synonyms: Łańcuchy lekkie immunoglobulin Łańcuchy lekkie kappa immunoglobuliny
pt-BR	Portuguese (Brazil)	Imunoglobulinas cadeias leves.kappa:ACnc:Pt:Soro:Ord:Imunoensaio Synonyms: ; Kappa LC; BJ Protein; BJP; Bence Jones protein; Arbitrary concentration; Point in time; Random; Serum; SR; Ql; Ordinal; QL; Qualitative; Qual; Screen; Enzyme immunoassay; ELISA; MEIA; SUDS; ELFA; IAA; Immune globulin; Imunoglbon; Immuno; Imunoglobn; Immunoglobin; Immunoglob; Chain; Chemistry
ru-RU	Russian (Russian Federation)	Иммуноглобулин легкие цепи.каппа:PrThr:ТчкВрм:Сыв:Пор:IA Synonyms: Порядковый Сыворотка Точка во времени;Момент
tr-TR	Turkish (Turkey)	İmmünglobulin hafif zincirler.kappa:MevcEşik:Zmlı:Ser:Srl:İA Synonyms: İmmünölçüm, immünoassay Mevcut
zh-CN	Chinese (China)	免疫球蛋白轻链.Kappa 型:存在情况或阈值:时间点:血清:序数型:免疫测定法 Synonyms: Bence Jones 氏蛋白;Bence Jones 蛋白;BJ 蛋白;B-J 蛋白;BJP;本周氏蛋白;本-周氏蛋白;本周氏蛋白（Bence Jones protein，BJ Protein，BJP）;本周蛋白;本-周蛋白 Ig Kappa LC;Kappa 型免疫球蛋白轻链;Kappa 型轻链;Kappa 轻链;κ型免疫球蛋白轻链;κ型轻链;κ轻链;免疫球蛋白轻链.Kappa;免疫球蛋白轻链.κ型;轻链.Kappa;轻链.Kappa 型;轻链.κ;轻链.κ型丙种球蛋白依次型;分类顺序型;定性的;序数型（或称等级型）;性质上的;有序型;有序性分类应答;有序性分类结果;秩次型;等级型;筛查;顺序型免疫测定;免疫分析法;免疫检定法;免疫检定;免疫试验;酶免疫测定法;酶免疫测定;酶免疫分析法;酶免疫检定法;酶免疫检定;酶免疫试验免疫球蛋白（Immunoglobulin，Ig）免疫球蛋白类化学;化学检验项目;化学检验项目类;化学类;化学试验;非刺激耐受型化学检验项目;非刺激耐受型化学检验项目类;非刺激耐受型化学试验;非刺激耐受型化学试验类存在情况;存在;存在与否;是否存在;阈值;界值;界限;阀值;临界值;存在情况（存在、存在与否、是否存在）或阈值（界值、界限、阀值、临界值）时刻;随机;随意;瞬间链

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LOINC Copyright

Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.